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We review how sensorimotor control is dictated by interacting neural populations, optimal feedback mechanisms, and the biomechanics of bodies. First, we outline the distributed anatomical loops that shuttle sensorimotor signals between…

Neurons and Cognition · Quantitative Biology 2025-09-19 Muhammad Noman Almani , John Lazzari , Jeff Walker , Shreya Saxena

Adaptive reasoning enables humans to flexibly adjust inference strategies when environmental rules or contexts change, yet its underlying neural dynamics remain unclear. This study investigated the neurophysiological mechanisms of adaptive…

Artificial Intelligence · Computer Science 2025-11-12 Jun-Young Kim , Young-Seok Kweon , Gi-Hwan Shin , Seong-Whan Lee

The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence…

Biological Physics · Physics 2007-05-23 Ulrich Hillenbrand , J. Leo van Hemmen

Active Inference is a closed-loop computational theoretical basis for understanding behaviour, based on agents with internal probabilistic generative models that encode their beliefs about how hidden states in their environment cause their…

Human-Computer Interaction · Computer Science 2024-12-20 Roderick Murray-Smith , John H. Williamson , Sebastian Stein

Using an underdamped active Ornstein-Uhlenbeck particle, we propose two information swimmer models having either external or internal feedback control and perform their numerical simulations. Depending on the velocity that is measured after…

Soft Condensed Matter · Physics 2025-04-08 Zhanglin Hou , Ziluo Zhang , Jun Li , Kento Yasuda , Shigeyuki Komura

Continuous-time reinforcement learning (CTRL) provides a natural framework for sequential decision-making in dynamic environments where interactions evolve continuously over time. While CTRL has shown growing empirical success, its ability…

Machine Learning · Computer Science 2025-12-04 Runze Zhao , Yue Yu , Ruhan Wang , Chunfeng Huang , Dongruo Zhou

Many high-performance human activities are executed with little or no external feedback: think of a figure skater landing a triple jump, a pitcher throwing a curveball for a strike, or a barista pouring latte art. To study the process of…

Artificial Intelligence · Computer Science 2025-12-10 Antonio Terpin , Raffaello D'Andrea

The stability of complex networks, from power grids to biological systems, is crucial for their proper functioning. It is thus important to control such systems to maintain or restore their stability. Traditional approaches rely on…

Optimization and Control · Mathematics 2025-09-23 Yuzhen Qin , Fabio Pasqualetti , Danielle S. Bassett , Marcel van Gerven

Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

Neurons and Cognition · Quantitative Biology 2019-10-22 Jens Wilting , Jonas Dehning , Joao Pinheiro Neto , Lucas Rudelt , Michael Wibral , Johannes Zierenberg , Viola Priesemann

Neurofeedback training (NFT) aims to teach self-regulation of brain activity through real-time feedback, but suffers from highly variable outcomes and poorly understood mechanisms, hampering its validation. To address these issues, we…

Neurons and Cognition · Quantitative Biology 2025-05-07 Côme Annicchiarico , Fabien Lotte , Jérémie Mattout

How biological networks achieve robust control despite relying on imperfect, local information remains an important open question. Here, we identify thermodynamic constraints that can curtail non-equilibrium steady-state responses so…

Statistical Mechanics · Physics 2026-05-27 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

This paper sets out a theory of how feedback cooling in the brain switches on consciousness. It explains how cooling reduces thermal noise to the point where macroscale quantum phenomena - crucially Bose-Einstein condensation and long-range…

Neurons and Cognition · Quantitative Biology 2024-06-05 Andrew Bell

Recently developed control methods with strong disturbance rejection capabilities provide a useful option for control design. The key lies in a general concept of disturbance and effective ways to estimate and compensate the disturbance.…

Optimization and Control · Mathematics 2018-01-19 Wuhua Hu , Eduardo F. Camacho , Lihua Xie

Conventional neuroimaging analyses have revealed the computational specificity of localized brain regions, exploiting the power of the subtraction technique in fMRI and event-related potential analyses in EEG. Moving beyond this convention,…

Neurons and Cognition · Quantitative Biology 2016-06-15 Javier O. Garcia , Justin Brooks , Scott Kerick , Tony Johnson , Tim Mullen , Jean M. Vettel

Feedback loops between population dynamics of individuals and their ecological environment are ubiquitously found in nature, and have shown profound effects on the resulting eco-evolutionary dynamics. Incorporating linear environmental…

Physics and Society · Physics 2020-07-01 Xin Wang , Zhiming Zheng , Feng Fu

The human brain exhibits large-scale spontaneous fluctuations that account for most of its total energy metabolism. Independent of any overt function, this immense ongoing activity likely creates or maintains a potential functional brain…

Neurons and Cognition · Quantitative Biology 2021-02-23 Ze Wang

We show that dynamical gain modulation of neurons' stimulus response is described as an information-theoretic cycle that generates entropy associated with the stimulus-related activity from entropy produced by the modulation. To articulate…

Neurons and Cognition · Quantitative Biology 2017-12-29 Hideaki Shimazaki

Many organisms navigate gradients by alternating straight motions (runs) with random reorientations (tumbles), transiently suppressing tumbles whenever attractant signal increases. This induces a functional coupling between movement and…

Cell Behavior · Quantitative Biology 2017-04-12 Junjiajia Long , Steven W. Zucker , Thierry Emonet

We investigate the decoherence of a spin 1/2 subsystem weakly coupled to an environment of many spins 1/2 with and without mutual coupling. The total system is closed, its state is pure and evolves under Schroedinger dynamics. Nevertheless,…

Quantum Physics · Physics 2009-11-11 Harry Schmidt , Guenter Mahler

The endeavor to understand the brain involves multiple collaborating research fields. Classically, synaptic plasticity rules derived by theoretical neuroscientists are evaluated in isolation on pattern classification tasks. This contrasts…

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