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A high level of physical detail in a molecular model improves its ability to perform high accuracy simulations, but can also significantly affect its complexity and computational cost. In some situations, it is worthwhile to add additional…

Computational Physics · Physics 2021-09-15 Owen C. Madin , Simon Boothroyd , Richard A. Messerly , John D. Chodera , Josh Fass , Michael R. Shirts

In Bayesian inference, predictive distributions are typically in the form of samples generated via Markov chain Monte Carlo (MCMC) or related algorithms. In this paper, we conduct a systematic analysis of how to make and evaluate…

Methodology · Statistics 2020-06-25 Fabian Krüger , Sebastian Lerch , Thordis L. Thorarinsdottir , Tilmann Gneiting

A Bayes factor is proposed for testing whether the effect of a key predictor variable on the dependent variable is linear or nonlinear, possibly while controlling for certain covariates. The test can be used (i) when one is interested in…

Methodology · Statistics 2021-09-16 Joris Mulder

We introduce a Bayesian prior distribution, the Logit-Normal continuous analogue of the spike-and-slab (LN-CASS), which enables flexible parameter estimation and variable/model selection in a variety of settings. We demonstrate its use and…

Applications · Statistics 2018-10-04 William Thomson , Sara Jabbari , Angela Taylor , Wiebke Arlt , David Smith

A key sticking point of Bayesian analysis is the choice of prior distribution, and there is a vast literature on potential defaults including uniform priors, Jeffreys' priors, reference priors, maximum entropy priors, and weakly informative…

Methodology · Statistics 2017-11-22 Andrew Gelman , Daniel Simpson , Michael Betancourt

Varying coefficient models (VCMs) are widely used for estimating nonlinear regression functions for functional data. Their Bayesian variants using Gaussian process priors on the functional coefficients, however, have received limited…

Methodology · Statistics 2022-03-01 Rajarshi Guhaniyogi , Cheng Li , Terrance D. Savitsky , Sanvesh Srivastava

Complex scientific models where the likelihood cannot be evaluated present a challenge for statistical inference. Over the past two decades, a wide range of algorithms have been proposed for learning parameters in computationally feasible…

Computation · Statistics 2021-12-16 Aden Forrow , Ruth E. Baker

Empirical Bayes inference is based on estimation of the parameters of an a priori distribution from the observed data. The estimation technique of the parameters of the prior, called hyperparameters, is based on the marginal distribution…

Systems and Control · Electrical Eng. & Systems 2025-11-06 Timofei Leahu , Giorgio Picci

Eliciting informative prior distributions for Bayesian inference can often be complex and challenging. While popular methods rely on asking experts probability based questions to quantify uncertainty, these methods are not without their…

Methodology · Statistics 2022-03-11 Julia R. Falconer , Eibe Frank , Devon L. L. Polaschek , Chaitanya Joshi

Maximum likelihood estimates (MLEs) are asymptotically normally distributed, and this property is used in meta-analyses to test the heterogeneity of estimates, either for a single cluster or for several sub-groups. More recently, MLEs for…

Statistics Theory · Mathematics 2022-02-28 Anthony J. Webster

Factor analysis is a flexible technique for assessment of multivariate dependence and codependence. Besides being an exploratory tool used to reduce the dimensionality of multivariate data, it allows estimation of common factors that often…

Applications · Statistics 2020-05-08 Vitor G. C. da Silva , Kelly C. M. Gonçalves , João B. M. Pereira

Discrete data are abundant and often arise as counts or rounded data. These data commonly exhibit complex distributional features such as zero-inflation, over-/under-dispersion, boundedness, and heaping, which render many parametric models…

Methodology · Statistics 2023-02-27 Daniel R. Kowal , Bohan Wu

Covariance matrix estimation arises in multivariate problems including multivariate normal sampling models and regression models where random effects are jointly modeled, e.g. random-intercept, random-slope models. A Bayesian analysis of…

Methodology · Statistics 2016-07-14 Ignacio Alvarez , Jarad Niemi , Matt Simpson

We develop simple methods for constructing likelihoods and parameter priors for learning about the parameters and structure of a Bayesian network. In particular, we introduce several assumptions that permit the construction of likelihoods…

Machine Learning · Computer Science 2021-07-01 David Heckerman , Dan Geiger

We consider the problem of static Bayesian inference for partially observed Levy-process models. We develop a methodology which allows one to infer static parameters and some states of the process, without a bias from the…

Computation · Statistics 2022-04-01 Hamza Ruzayqat , Ajay Jasra

Motivated by the analysis of the distribution of university grades, which is usually asymmetric, we discuss two informative priors for the shape parameter of the skew-normal distribution, showing that they lead to closed-form…

Methodology · Statistics 2013-05-15 Antonio Canale , Bruno Scarpa

A statistical method for the elicitation of priors in Bayesian generalised linear models (GLMs) and extensions is proposed. Probabilistic predictions are elicited from the expert to parametrise a multivariate t prior distribution for the…

Methodology · Statistics 2025-02-21 Geoffrey R. Hosack

Stochastic processes are a flexible and widely used family of models for statistical modeling. While stochastic processes offer attractive properties such as inclusion of uncertainty properties, their inference is typically intractable,…

Methodology · Statistics 2026-02-10 Teemu Härkönen , Simo Särkkä

We describe Bayes factors based on z, t, $\chi^2$, and F statistics when non-local moment prior distributions are used to define alternative hypotheses. The non-local alternative prior distributions are centered on standardized effects. The…

Methodology · Statistics 2024-07-26 Saptati Datta , Rachael Shudde , Valen E. Johnson

Likelihood-free methods, such as approximate Bayesian computation, are powerful tools for practical inference problems with intractable likelihood functions. Markov chain Monte Carlo and sequential Monte Carlo variants of approximate…

Computation · Statistics 2019-02-26 David J. Warne , Ruth E. Baker , Matthew J. Simpson