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We propose Dirichlet Process mixtures of Generalized Linear Models (DP-GLM), a new method of nonparametric regression that accommodates continuous and categorical inputs, and responses that can be modeled by a generalized linear model. We…

Machine Learning · Statistics 2010-07-16 Lauren A. Hannah , David M. Blei , Warren B. Powell

Consider a compound Poisson process with jump measure $\nu$ supported by finitely many positive integers. We propose a method for estimating $\nu$ from a single, equidistantly sampled trajectory and develop associated statistical…

Statistics Theory · Mathematics 2009-09-29 Werner Ehm , Benjamin Staude , Stefan Rotter

Parallel recordings of neural spike counts have revealed the existence of context-dependent noise correlations in neural populations. Theories of population coding have also shown that such correlations can impact the information encoded by…

Machine Learning · Computer Science 2025-07-30 Sacha Sokoloski , Ruben Coen-Cagli

Inferring the mechanisms underlying physiological and pathological processes in the brain from recorded electrical activity is challenging. Bayesian model selection and dynamic causal modelling aim to identify likely biophysical models to…

Neurons and Cognition · Quantitative Biology 2023-06-29 Matthew G. Thomas

Can we use spiking neural networks (SNN) as generative models of multi-neuronal recordings, while taking into account that most neurons are unobserved? Modeling the unobserved neurons with large pools of hidden spiking neurons leads to…

Neurons and Cognition · Quantitative Biology 2023-01-10 Shuqi Wang , Valentin Schmutz , Guillaume Bellec , Wulfram Gerstner

A body of recent work in modeling neural activity focuses on recovering low-dimensional latent features that capture the statistical structure of large-scale neural populations. Most such approaches have focused on linear generative models,…

Neurons and Cognition · Quantitative Biology 2016-10-26 Yuanjun Gao , Evan Archer , Liam Paninski , John P. Cunningham

Probabilistic approaches for handling count-valued time sequences have attracted amounts of research attentions because their ability to infer explainable latent structures and to estimate uncertainties, and thus are especially suitable for…

Machine Learning · Computer Science 2024-05-24 Jiahao Wang , Sikun Yang , Heinz Koeppl , Xiuzhen Cheng , Pengfei Hu , Guoming Zhang

Neural population activity exhibits complex, nonlinear dynamics, varying in time, over trials, and across experimental conditions. Here, we develop Conditionally Linear Dynamical System (CLDS) models as a general-purpose method to…

Neurons and Cognition · Quantitative Biology 2025-10-31 Victor Geadah , Amin Nejatbakhsh , David Lipshutz , Jonathan W. Pillow , Alex H. Williams

Neural spike trains, which are sequences of very brief jumps in voltage across the cell membrane, were one of the motivating applications for the development of point process methodology. Early work required the assumption of stationarity,…

Applications · Statistics 2011-08-01 Robert E. Kass , Ryan C. Kelly , Wei-Liem Loh

Simultaneous recordings from multiple neural units allow us to investigate the activity of very large neural ensembles. To understand how large ensembles of neurons process sensory information, it is necessary to develop suitable…

Neurons and Cognition · Quantitative Biology 2013-05-30 Fernando Montani , Elena Phoka , Mariela Portesi , Simon R. Schultz

The current state-of-the-art in neurophysiological data collection allows for simultaneous recording of tens to hundreds of neurons, for which point processes are an appropriate statistical modelling framework. However, existing point…

Methodology · Statistics 2022-06-22 Reza Ramezan , Meixi Chen , Martin Lysy , Paul Marriott

To gain a deeper understanding of the behavior and learning dynamics of (deep) artificial neural networks, it is valuable to employ mathematical abstractions and models. These tools provide a simplified perspective on network performance…

Machine Learning · Computer Science 2023-08-03 Stephan Johann Lehmler , Muhammad Saif-ur-Rehman , Tobias Glasmachers , Ioannis Iossifidis

We propose stochastic, non-parametric activation functions that are fully learnable and individual to each neuron. Complexity and the risk of overfitting are controlled by placing a Gaussian process prior over these functions. The result is…

Machine Learning · Statistics 2017-12-01 Sebastian Urban , Marcus Basalla , Patrick van der Smagt

There has been a strong push recently to examine biological scale simulations of neuromorphic algorithms to achieve stronger inference capabilities. This paper presents a set of piecewise linear spiking neuron models, which can reproduce…

Machine Learning · Computer Science 2012-12-18 Hamid Soleimani , Arash Ahmadi , Mohammad Bavandpour

A neural network (NN) is a parameterised function that can be tuned via gradient descent to approximate a labelled collection of data with high precision. A Gaussian process (GP), on the other hand, is a probabilistic model that defines a…

Machine Learning · Computer Science 2018-07-05 Marta Garnelo , Jonathan Schwarz , Dan Rosenbaum , Fabio Viola , Danilo J. Rezende , S. M. Ali Eslami , Yee Whye Teh

Detection and modeling of change-points in time-series can be considerably challenging. In this paper we approach this problem by incorporating the class of Dynamic Generalized Linear Models (DGLM) into the well know class of Product…

The dynamic range of stimulus processing in living organisms is much larger than a single neural network can explain. For a generic, tunable spiking network we derive that while the dynamic range is maximal at criticality, the interval of…

Disordered Systems and Neural Networks · Physics 2020-02-12 Johannes Zierenberg , Jens Wilting , Viola Priesemann , Anna Levina

Neural computations emerge from myriads of neuronal interactions occurring in intricate spiking networks. Due to the inherent complexity of neural models, relating the spiking activity of a network to its structure requires simplifying…

Dynamical Systems · Mathematics 2019-02-12 François Baccelli , Thibaud Taillefumier

Towards energy-efficient artificial intelligence similar to the human brain, the bio-inspired spiking neural networks (SNNs) have advantages of biological plausibility, event-driven sparsity, and binary activation. Recently, large-scale…

Neural and Evolutionary Computing · Computer Science 2024-06-06 Xingrun Xing , Zheng Zhang , Ziyi Ni , Shitao Xiao , Yiming Ju , Siqi Fan , Yequan Wang , Jiajun Zhang , Guoqi Li

Approaches to predicting neuronal spike responses commonly use a Poisson learning objective. This objective quantizes responses into spike counts within a fixed summation interval, typically on the order of 10 to 100 milliseconds in…

Neurons and Cognition · Quantitative Biology 2024-07-03 Kevin Doran , Marvin Seifert , Carola A. M. Yovanovich , Tom Baden