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High-dimensional data of discrete and skewed nature is commonly encountered in high-throughput sequencing studies. Analyzing the network itself or the interplay between genes in this type of data continues to present many challenges. As…

Methodology · Statistics 2017-12-01 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Sanjeena Subedi

Sparse covariance matrices play crucial roles by encoding the interdependencies between variables in numerous fields such as genetics and neuroscience. Despite substantial studies on sparse covariance matrices, existing methods face several…

Methodology · Statistics 2026-03-03 Rakheon Kim , Irina Gaynanova

In multivariate statistics, the question of finding direct interactions can be formulated as a problem of network inference - or network reconstruction - for which the Gaussian graphical model (GGM) provides a canonical framework.…

Methodology · Statistics 2018-06-11 Julien Chiquet , Mahendra Mariadassou , Stéphane Robin

We propose a general framework for non-normal multivariate data analysis called multivariate covariance generalized linear models (McGLMs), designed to handle multivariate response variables, along with a wide range of temporal and spatial…

Methodology · Statistics 2017-04-25 Wagner Hugo Bonat , Bent Jørgensen

Count data is prevalent in various fields like ecology, medical research, and genomics. In high-dimensional settings, where the number of features exceeds the sample size, feature selection becomes essential. While frequentist methods like…

Methodology · Statistics 2024-10-22 The Tien Mai

Relational data characterized by directed edges with count measurements are common in social science. Most existing methods either assume the count edges are derived from continuous random variables or model the edge dependency by…

Methodology · Statistics 2025-02-18 Wenqin Du , Bailey K. Fosdick , Wen Zhou

A Poisson autoregressive (PAR) model accounting for discreteness and autocorrelation of count time series data is typically estimated in the state-space modelling framework through extended Kalman filter. However, because of the complex…

Methodology · Statistics 2025-03-05 Paolo Victor T. Redondo , Joseph Ryan G. Lansangan , Erniel B. Barrios

In regression analysis of counts, a lack of simple and efficient algorithms for posterior computation has made Bayesian approaches appear unattractive and thus underdeveloped. We propose a lognormal and gamma mixed negative binomial (NB)…

Applications · Statistics 2012-07-03 Mingyuan Zhou , Lingbo Li , David Dunson , Lawrence Carin

This paper describes a compound Poisson-based random effects structure for modeling zero-inflated data. Data with large proportion of zeros are found in many fields of applied statistics, for example in ecology when trying to model and…

Applications · Statistics 2009-07-29 Marie-Pierre Etienne , Eric Parent , Benoit Hugues , Bernier Jacques

A new multivariate integer-valued Generalized AutoRegressive Conditional Heteroscedastic process based on a multivariate Poisson generalized inverse Gaussian distribution is proposed. The estimation of parameters of the proposed…

Computation · Statistics 2023-07-03 Yuhyeong Jang , Raanju R. Sundararajan , Wagner Barreto-Souza

Event counts are response variables with non-negative integer values representing the number of times that an event occurs within a fixed domain such as a time interval, a geographical area or a cell of a contingency table. Analysis of…

Modeling count data is important in physics and other scientific disciplines, where measurements often involve discrete, non-negative quantities such as photon or neutrino detection events. Traditional parametric approaches can be trained…

Data Analysis, Statistics and Probability · Physics 2026-02-10 Anushka Saha , Abhijith Gandrakota , Alexandre V. Morozov

We propose a novel statistical inference methodology for multiway count data that is corrupted by false zeros that are indistinguishable from true zero counts. Our approach consists of zero-truncating the Poisson distribution to neglect all…

Methodology · Statistics 2025-09-10 Oscar López , Daniel M. Dunlavy , Richard B. Lehoucq

Three-way data structures, characterized by three entities, the units, the variables and the occasions, are frequent in biological studies. In RNA sequencing, three-way data structures are obtained when high-throughput transcriptome…

Methodology · Statistics 2022-06-22 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Xiaoke Qin , Sanjeena Subedi

The bivariate Gaussian distribution has been a key model for many developments in statistics. However, many real-world phenomena generate data that follow asymmetric distributions, and consequently bivariate normal model is inappropriate in…

Methodology · Statistics 2022-12-08 Roberto Vila , Narayanaswamy Balakrishnan , Helton Saulo , Ana Protazio

Sparse linear regression is a central problem in high-dimensional statistics. We study the correlated random design setting, where the covariates are drawn from a multivariate Gaussian $N(0,\Sigma)$, and we seek an estimator with small…

Data Structures and Algorithms · Computer Science 2023-05-29 Jonathan Kelner , Frederic Koehler , Raghu Meka , Dhruv Rohatgi

I begin my discussion by summarizing the methodology proposed and new distributional results on multivariate log-Gamma derived in the paper. Then, I draw an interesting connection between their work with mean field variational Bayes.…

Methodology · Statistics 2018-03-15 William Weimin Yoo

In this work, we consider a multivariate regression model with one-sided errors. We assume for the regression function to lie in a general H\"{o}lder class and estimate it via a nonparametric local polynomial approach that consists of…

Statistics Theory · Mathematics 2021-02-11 Leonie Selk , Charles Tillier , Orlando Marigliano

This paper considers estimation for linear regression analysis with covariate measurement error arising from Poisson surrogates. We consider cases where covariates follow a conditional Poisson distribution, capturing non-Gaussian and…

Statistics Theory · Mathematics 2025-09-08 Aijun Yang , Mary Lesperance , Farouk S. Nathoo

We propose a new class of estimators of the multivariate response linear regression coefficient matrix that exploits the assumption that the response and predictors have a joint multivariate Normal distribution. This allows us to indirectly…

Methodology · Statistics 2015-07-17 Aaron J. Molstad , Adam J. Rothman