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Our aim is to present a new model which encompasses pace optimization and motor control effort for a runner on a fixed distance. We see that for long races, the long term behaviour is well approximated by a turnpike problem. We provide…

Optimization and Control · Mathematics 2021-05-06 Amandine Aftalion , Emmanuel Trélat

Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to…

Machine Learning · Computer Science 2020-09-11 Joshua D. Cardosi , Herman Shen , Jonathan I. Groner , Megan Armstrong , Henry Xiang

Time-to-event models are a popular tool to analyse data where the outcome variable is the time to the occurrence of a specific event of interest. Here we focus on the analysis of time-to-event outcomes that are either intrisically discrete…

Applications · Statistics 2017-04-14 Moritz Berger , Matthias Schmid

The causal effect of an intervention (treatment/exposure) on an outcome can be estimated by: i) specifying knowledge about the data-generating process; ii) assessing under what assumptions a target quantity, such as for example a causal…

Methodology · Statistics 2021-03-05 Michael Schomaker

As cancer patient survival improves, late effects from treatment are becoming the next clinical challenge. Chemotherapy and radiotherapy, for example, potentially increase the risk of both morbidity and mortality from second malignancies…

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

Machine Learning · Statistics 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

Problem lists are intended to provide clinicians with a relevant summary of patient medical issues and are embedded in many electronic health record systems. Despite their importance, problem lists are often cluttered with resolved or…

Information Retrieval · Computer Science 2020-08-05 Justin Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Marginal structural models (MSMs) are widely used in observational studies to estimate the causal effect of time-varying treatments. Despite its popularity, limited attention has been paid to summarizing the treatment history in the outcome…

Methodology · Statistics 2024-09-18 Jiewen Liu , Todd A. Miano , Stephen Griffiths , Michael G. S. Shashaty , Wei Yang

Psychometric assessment instruments aid clinicians by providing methods of assessing the future risk of adverse events such as aggression. Existing machine learning approaches have treated this as a classification problem, predicting the…

Machine Learning · Computer Science 2023-12-05 Aidan Quinn , Melanie Simmons , Benjamin Spivak , Christoph Bergmeir

Online mental health treatment has the premise to meet the increasing demand for mental health treatment at a lower cost than traditional treatment. However, online treatment suffers from high drop-out rates, which might negate their cost…

Computation · Statistics 2018-09-13 Dennis Becker

In this paper, machine learning models are used to predict outcomes for patients with persistent post-concussion syndrome (PCS). Patients had sustained a concussion at an average of two to three months before the study. By utilizing…

Quantitative Methods · Quantitative Biology 2021-08-06 Minhong Kim

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Statistical boosting algorithms have triggered a lot of research during the last decade. They combine a powerful machine-learning approach with classical statistical modelling, offering various practical advantages like automated variable…

Understanding and quantifying cause and effect is an important problem in many domains. The generally-agreed solution to this problem is to perform a randomised controlled trial. However, even when randomised controlled trials can be…

Machine Learning · Statistics 2023-02-22 Graham Van Goffrier , Lucas Maystre , Ciarán Gilligan-Lee

Ordinal measurements are common outcomes in studies within psychology, as well as in the social and behavioral sciences. Choosing an appropriate regression model for analysing such data poses a difficult task. This paper aims to facilitate…

Methodology · Statistics 2026-03-03 Stefan Inerle , Markus Pauly , Moritz Berger

This article studies the estimation of the causal effect of a time-varying treatment on time-to-an-event or on some other continuously distributed outcome. The paper applies to the situation where treatment is repeatedly adapted to…

Statistics Theory · Mathematics 2008-06-19 Judith J. Lok

The propensity score analysis is one of the most widely used methods for studying the causal treatment effect in observational studies. This paper studies treatment effect estimation with the method of matching weights. This method…

Methodology · Statistics 2011-05-17 Liang Li

Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy…

Statistical models are used to produce estimates of demographic and global health indicators in populations with limited data. Such models integrate multiple data sources to produce estimates and forecasts with uncertainty based on model…

Methodology · Statistics 2024-12-02 Leontine Alkema , Herbert Susmann , Evan Ray

Clinical prognostic models help inform decision-making by estimating a patient's risk of experiencing an outcome in the future. The net benefit is increasingly being used to assess the clinical utility of models. By calculating an…

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