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We consider two finite population Markov chain models, the two-island Wright-Fisher model with mutation, and the seed-bank model with mutation. Despite the relatively simple descriptions of the two processes, the the exact form of their…

Probability · Mathematics 2024-05-30 Han L. Gan , Maite Wilke-Berenguer

The Wright-Fisher model, originating in Wright (1931) is one of the canonical probabilistic models used in mathematical population genetics to study how genetic type frequencies evolve in time. In this paper we bound the rate of convergence…

Probability · Mathematics 2023-12-19 Anton Braverman , Han L. Gan

We provide a general theorem bounding the error in the approximation of a random measure of interest--for example, the empirical population measure of types in a Wright-Fisher model--and a Dirichlet process, which is a measure having…

Probability · Mathematics 2020-07-07 Han L. Gan , Nathan Ross

We study a class of evolution models, where the breeding process involves an arbitrary exchangeable process, allowing for mutations to appear. The population size $n$ is fixed, hence after breeding, selection is applied. Individuals are…

Probability · Mathematics 2022-05-03 Daniela Bertacchi , Juri Lember , Fabio Zucca

The stationary distribution of a sample taken from a Wright-Fisher diffusion with general small mutation rates is found using a coalescent approach. The approximation is equivalent to having at most one mutation in the coalescent tree to…

Populations and Evolution · Quantitative Biology 2018-10-31 Conrad J. Burden , Robert C. Griffiths

We study a class of Cannings models with population size $N$ having a mixed multinomial offspring distribution with random success probabilities $W_1,\ldots,W_N$ induced by independent and identically distributed positive random variables…

Probability · Mathematics 2021-10-01 Thierry Huillet , Martin Möhle

We study the population genetics of two neutral alleles under reversible mutation in the \Lambda-processes, a population model that features a skewed offspring distribution. We describe the shape of the equilibrium allele frequency…

Populations and Evolution · Quantitative Biology 2013-06-21 Ricky Der , Joshua B. Plotkin

Diffusion theory is a central tool of modern population genetics, yielding simple expressions for fixation probabilities and other quantities that are not easily derived from the underlying Wright-Fisher model. Unfortunately, the textbook…

Populations and Evolution · Quantitative Biology 2022-12-19 Camila Bräutigam , Matteo Smerlak

The recently introduced two-parameter Poisson-Dirichlet diffusion extends the infinitely-many-neutral-alleles model, related to Kingman's distribution and to Fleming-Viot processes. The role of the additional parameter has been shown to…

Probability · Mathematics 2016-01-26 Pierpaolo De Blasi , Matteo Ruggiero , Dario Spano'

The two-parameter Poisson--Dirichlet diffusion, introduced in 2009 by Petrov, extends the infinitely-many-neutral-alleles diffusion model, related to Kingman's one-parameter Poisson--Dirichlet distribution and to certain Fleming--Viot…

The stationary distribution of the diffusion limit of the 2-island, 2-allele Wright-Fisher with small but otherwise arbitrary mutation and migration rates is investigated. Following a method developed by Burden and Tang (2016, 2017) for…

Populations and Evolution · Quantitative Biology 2018-09-27 Conrad J. Burden , Robert C. Griffiths

A number of discrete time, finite population size models in genetics describing the dynamics of allele frequencies are known to converge (subject to suitable scaling) to a diffusion process in the infinite population limit, termed the…

Probability · Mathematics 2021-09-14 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spano

We construct a new class of infinite-dimensional diffusions taking values in a generalized Kingman simplex. Our model describes the temporal evolution of the relative frequencies of infinitely-many types which are "labeled" by an arbitrary…

Probability · Mathematics 2026-02-25 Cristina Costantini , Matteo Ruggiero

Near the beginning of the century, Wright and Fisher devised an elegant, mathematically tractable model of gene reproduction and replacement that laid the foundation for contemporary population genetics. The Wright-Fisher model and its…

Probability · Mathematics 2013-12-23 Todd L. Parsons

We introduce a multi-allele Wright-Fisher model with non-recurrent, reversible mutation and directional selection. In this setting, the allele frequencies at a single locus track the path of a hybrid jump-diffusion process with state space…

Probability · Mathematics 2023-02-16 Ingemar Kaj , Carina F. Mugal , Rebekka Müller

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

We are interested in the long-time behavior of a diploid population with sexual reproduction, characterized by its genotype composition at one bi-allelic locus. The population is modeled by a 3-dimensional birth-and-death process with…

Probability · Mathematics 2013-09-16 Camille Coron

A multi-type neutral Cannings population model with mutation and fixed subpopulation sizes is analyzed. Under appropriate conditions, as all subpopulation sizes tend to infinity, the ancestral process, properly time-scaled, converges to a…

Probability · Mathematics 2023-04-13 Martin Möhle

To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

We study branching Markov chains on a countable state space (space of types) $\mathscr{X}$, with the focus on the qualitative aspects of the limit behaviour of the evolving empirical population distributions. No conditions are imposed on…

Probability · Mathematics 2025-07-30 Vadim A. Kaimanovich , Wolfgang Woess
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