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We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

The outbreak of an infectious disease in a human population can lead to individuals responding with preventive measures in an attempt to avoid getting infected. This leads to changes in contact patterns. However, as we show in this paper,…

Populations and Evolution · Quantitative Biology 2018-05-15 Ka Yin Leung , Frank Ball , David Sirl , Tom Britton

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

Physics and Society · Physics 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

General Economics · Economics 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of…

This paper revisits a longstanding problem of interest concerning the distributed control of an epidemic process on human contact networks. Due to the stochastic nature and combinatorial complexity of the problem, finding optimal policies…

Optimization and Control · Mathematics 2022-12-12 Mohammad Mubarak , Cameron Nowzari

Network--based epidemic models that account for heterogeneous contact patterns are extensively used to predict and control the diffusion of infectious diseases. We use census and survey data to reconstruct a geo--referenced and…

Social and Information Networks · Computer Science 2026-05-19 Alessandro Celestini , Francesca Colaiori , Stefano Guarino , Enrico Mastrostefano , Lena Rebecca Zastrow

Contacts between individuals play an important role in determining how infectious diseases spread. Various methods to gather data on such contacts co-exist, from surveys to wearable sensors. Comparisons of data obtained by different methods…

Physics and Society · Physics 2016-04-18 Julie Fournet , Alain Barrat

Changes in human behavior are increasingly recognized as a major determinant of epidemic dynamics. Although collective activity can be modified through imposed measures to control epidemic progression, spontaneous changes can also arise as…

Populations and Evolution · Quantitative Biology 2021-05-25 Susanna Manrubia , Damián H. Zanette

Traditional biomedical approaches treat diseases in isolation, but the importance of synergistic disease interactions is now recognized. As a first step we present and analyze a simple coinfection model for two diseases affecting…

Dynamical Systems · Mathematics 2015-04-21 Marcos Marvá , Ezio Venturino , Rafael Bravo de la Parra

The spread of certain diseases can be promoted, in some cases substantially, by prior infection with another disease. One example is that of HIV, whose immunosuppressant effects significantly increase the chances of infection with other…

Physics and Society · Physics 2014-08-04 M. E. J. Newman , C. R. Ferrario

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

We consider interacting population systems of predator-prey type, presenting four models of control strategies for epidemics among the prey. In particular to contain the transmissible disease, safety niches are considered, assuming they…

Populations and Evolution · Quantitative Biology 2014-03-04 Iulia Martina Bulai , Roberto Cavoretto , Bruna Chialva , Davide Duma , Ezio Venturino

Epidemics exhibit interconnected processes that operate at multiple time and organizational scales, a hallmark of complex adaptive systems. Modern epidemiological modeling frameworks incorporate feedback between individual-level behavioral…

Dynamical Systems · Mathematics 2025-03-07 Baltazar Espinoza , Roger Sanchez , Jimmy Calvo-Monge , Fabio Sanchez

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

Under limited available resources, strategies for mitigating the propagation of an epidemic such as random testing and contact tracing become inefficient. Here, we propose to accurately allocate the resources by computing over time an…

Physics and Society · Physics 2023-11-07 Gabriela Bayolo Soler , Miraine Dávila Felipe , Ghislaine Gayraud