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Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential for development. We provide a…

Biological Physics · Physics 2012-04-17 Shenshen Wang , Peter G. Wolynes

We investigate the transmission properties of quasiperiodic or aperiodic structures based on graphene arranged according to the Cantor sequence. In particular, we have found self-similar behaviour in the transmission spectra, and most…

Mesoscale and Nanoscale Physics · Physics 2016-02-17 R. Rodríguez-González , I. Rodríguez-Vargas , D. S. Díaz-Guerrero , L. M. Gaggero-Sager

Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

Voltage-gated sodium (Na$_\mathrm{v}$) channels are responsible for the depolarizing phase of the action potential in most nerve cells, and Na$_\mathrm{v}$ channel localization to the axon initial segment is vital to action potential…

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

In living matter, shape fluctuations induced by acto-myosin are usually studied in vitro via reconstituted gels, whose properties are controlled by changing the concentrations of actin, myosin and cross-linkers. Such an approach…

Biological Physics · Physics 2018-03-01 É. Fodor , V. Mehandia , J. Comelles , R. Thiagarajan , N. S. Gov , P. Visco , F. van Wijland , D. Riveline

There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synaptic connection between two neurons. The membrane shape and…

Quantitative Methods · Quantitative Biology 2026-02-27 Matthew Hur , Thomas Bartol , Padmini Rangamani , Terrence Sejnowski , Eric Mjolsness

Actin is a key component of the cytoskeleton, which plays central roles in cell motility, division, growth, and tensile strength. To enable this wide range of transient mechanical processes and properties, networks of actin filaments…

A salient feature of skeletal muscles is their ability to take up an applied slack in a microsecond timescale. Behind this remarkably fast adaptation is a collective folding in a bundle of elastically interacting bistable elements. Since…

Biological Physics · Physics 2019-12-18 Hudson Borja da Rocha , Lev Truskinovsky

The cytoskeleton -- a composite network of biopolymers, molecular motors, and associated binding proteins -- is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous…

Many processes in eukaryotic cells, including cell motility, rely on the growth of branched actin networks from surfaces. Despite its central role the mechano-chemical coupling mechanisms which guide the growth process are poorly…

Soft Condensed Matter · Physics 2015-06-23 Karin John , Denis Caillerie , Chaouqi Misbah

Recent studies have revealed the complex structure of nerve signals in axons. There is experimental evidence that the propagation of an electrical signal (action potential) is accompanied by mechanical and thermal effects. In this paper,…

Biological Physics · Physics 2020-09-21 Jüri Engelbrecht , Kert Tamm , Tanel Peets

Computer simulations can aid in understanding how collective materials properties emerge from interactions between simple constituents. Here, we introduce a coarse-grained model that enables simulation of networks of actin filaments, myosin…

Biological Physics · Physics 2018-12-07 Simon L. Freedman , Shiladitya Banerjee , Glen M. Hocky , Aaron R. Dinner

The cytoskeleton provides eukaryotic cells with mechanical support and helps them perform their biological functions. It is a network of semiflexible polar protein filaments and many accessory proteins that bind to these filaments, regulate…

Cell Behavior · Quantitative Biology 2008-01-01 Tanniemola B. Liverpool , M. Cristina Marchetti

The spatiotemporal organisation of proteins and lipids on the cell surface has direct functional consequences for signaling, sorting and endocytosis. Earlier studies have shown that multiple types of membrane proteins including…

Soft Condensed Matter · Physics 2022-09-14 Suvrajit Saha , Amit Das , Chandrima Patra , Anupama Ambika Anilkumar , Parijat Sil , Satyajit Mayor , Madan Rao

The actin cortex is a thin layer of actin, myosin, and actin binding proteins that underlies the membrane of most animal cells. It is highly dynamic and can undergo remodelling on time-scales of tens of seconds thanks to protein turnover…

Cell Behavior · Quantitative Biology 2020-06-24 Manasi Kelkar , Pierre Bohec , Guillaume Charras

Axonal growth and guidance at the ventral floor plate is here followed $\textit{in vivo}$ in real time at high resolution by light-sheet microscopy along several hundred micrometers of the zebrafish spinal cord. The recordings show the…

Neurons and Cognition · Quantitative Biology 2021-07-13 Søren S. L. Andersen

Spin superfluidity, i.e., coherent spin transport mediated by topologically stable textures, is limited by parasitic anisotropies rooted in relativistic interactions and spatial inhomogeneities. Since structural disorder in amorphous…

Mesoscale and Nanoscale Physics · Physics 2018-08-29 Hector Ochoa , Ricardo Zarzuela , Yaroslav Tserkovnyak

We use energy discrimination of keV ions transmitted through a thin, single-crystalline silicon membrane to correlate specific angular distribution patterns formed in channelling geometry with trajectory-dependent electronic energy loss.…

Applied Physics · Physics 2022-11-30 Radek Holeňák , Svenja Lohmann , Kristina Komander , Daniel Primetzhofer

Intervalley scattering of carriers in graphene at `top' adatoms may give rise to a hidden Kekul\'e ordering pattern in the adatom positions. This ordering is the result of a rapid modulation in the electron-mediated interaction between…

Mesoscale and Nanoscale Physics · Physics 2018-05-02 L. González-Árraga , F. Guinea , P. San-Jose
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