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Unstructured pruning has the limitation of dealing with the sparse and irregular weights. By contrast, structured pruning can help eliminate this drawback but it requires complex criterion to determine which components to be pruned. To this…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Weichao Lan , Yiu-ming Cheung , Juyong Jiang

High-throughput sequencing technologies have led to explosive growth of genomic databases; one of which will soon reach hundreds of terabytes. For many applications we want to build and store indexes of these databases but constructing such…

Data Structures and Algorithms · Computer Science 2018-11-19 Christina Boucher , Travis Gagie , Alan Kuhnle , Ben Langmead , Giovanni Manzini , Taher Mun

As training deep learning models on large dataset takes a lot of time and resources, it is desired to construct a small synthetic dataset with which we can train deep learning models sufficiently. There are recent works that have explored…

Machine Learning · Computer Science 2022-09-12 Wei Jin , Xianfeng Tang , Haoming Jiang , Zheng Li , Danqing Zhang , Jiliang Tang , Bing Yin

We present a deep learning model to automatically generate computer models of the human heart from patient imaging data with an emphasis on its capability to generate thin-walled cardiac structures. Our method works by deforming a template…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Arjun Narayanan , Fanwei Kong , Shawn Shadden

Patient-specific cardiac modeling combines geometries of the heart derived from medical images and biophysical simulations to predict various aspects of cardiac function. However, generating simulation-suitable models of the heart from…

Image and Video Processing · Electrical Eng. & Systems 2023-11-09 Fanwei Kong , Shawn Shadden

In applications such as molecule design or drug discovery, it is desirable to have an algorithm which recommends new candidate molecules based on the results of past tests. These molecules first need to be synthesized and then tested for…

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

Graph mining for structural patterns is a fundamental task in many applications. Compilation-based graph mining systems, represented by AutoMine, generate specialized algorithms for the provided patterns and substantially outperform other…

Performance · Computer Science 2019-12-02 Daniel Mawhirter , Sam Reinehr , Connor Holmes , Tongping Liu , Bo Wu

In this paper we propose and study a new complexity model for approximation algorithms. The main motivation are practical problems over large data sets that need to be solved many times for different scenarios, e.g., many multicast trees…

Data Structures and Algorithms · Computer Science 2010-06-18 Marek Cygan , Lukasz Kowalik , Marcin Mucha , Marcin Pilipczuk , Piotr Sankowski

Imitation learning from a large set of human demonstrations has proved to be an effective paradigm for building capable robot agents. However, the demonstrations can be extremely costly and time-consuming to collect. We introduce MimicGen,…

The genome-scale metabolic model with protein constraint (PC-model) has been increasingly popular for microbial metabolic simulations. We present PROSO Toolbox, a unified and simple-to-use PC-model toolbox that takes any high-quality…

Molecular Networks · Quantitative Biology 2023-08-30 Haoyang Yao , Laurence Yang

Let $V$ be a finite set of points in the plane. We present a 2-local algorithm that constructs a plane $\frac{4 \pi \sqrt{3}}{9}$-spanner of the unit-disk graph $\UDG(V)$. This algorithm makes only one round of communication and each point…

Computational Geometry · Computer Science 2008-09-18 Prosenjit Bose , Paz Carmi , Michiel Smid , Daming Xu

The repeat content and heterozygosity rate of a target genome are important factors in determining the feasibility of achieving a complete telomere-to-telomere assembly. The mathematical relationship between the required coverage and read…

Information Theory · Computer Science 2025-04-08 Daanish Mahajan , Chirag Jain , Navin Kashyap

Dual-species single-atom array in optical tweezers has several advantages over the single-species atom array as a platform for quantum computing and quantum simulation. Thus, creating the defect-free dual-species single-atom array with atom…

Quantum Physics · Physics 2022-07-27 Zhi-Jin Tao , Li-Geng Yu , Peng-Xu , Jia-Yi Hou , Xiao-Dong He , Ming-Sheng Zhan

Graph kernels are often used in bioinformatics and network applications to measure the similarity between graphs; therefore, they may be used to construct efficient graph classifiers. Many graph kernels have been developed thus far, but to…

Quantum Physics · Physics 2022-11-01 Kaito Kishi , Takahiko Satoh , Rudy Raymond , Naoki Yamamoto , Yasubumi Sakakibara

Quantifying how hard it is to build a molecular graph matters for biosignature detection, chemical complexity, and cheminformatics. We present an exact, scalable algorithm to compute the molecular assembly index (MA) which prioritizes the…

Data Structures and Algorithms · Computer Science 2025-08-19 Ian Seet , Keith Y. Patarroyo , Gage Siebert , Sara I. Walker , Leroy Cronin

In order to associate complex traits with genetic polymorphisms, genome-wide association studies process huge datasets involving tens of thousands of individuals genotyped for millions of polymorphisms. When handling these datasets, which…

Computational Engineering, Finance, and Science · Computer Science 2013-05-02 Elmar Peise , Diego Fabregat , Yurii Aulchenko , Paolo Bientinesi

In order to support the real-time interaction with LLMs and the instant search or the instant recommendation on social media, it becomes an imminent problem to build a k-NN graph or an indexing graph for the massive number of vectorized…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-21 Cheng Zhang , Wan-Lei Zhao , Shihai Xiao , Jiajie Yao , Xuecang Zhang

Binary time series data are very common in many applications, and are typically modelled independently via a Bernoulli process with a single probability of success. However, the probability of a success can be dependent on the outcome…

Methodology · Statistics 2024-06-12 Louise Kimpton , Peter Challenor , Henry Wynn

We consider the enumeration of maximal bipartite cliques (bicliques) from a large graph, a task central to many practical data mining problems in social network analysis and bioinformatics. We present novel parallel algorithms for the…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-04-22 Arko Provo Mukherjee , Srikanta Tirthapura