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Unstructured pruning has the limitation of dealing with the sparse and irregular weights. By contrast, structured pruning can help eliminate this drawback but it requires complex criterion to determine which components to be pruned. To this…
High-throughput sequencing technologies have led to explosive growth of genomic databases; one of which will soon reach hundreds of terabytes. For many applications we want to build and store indexes of these databases but constructing such…
As training deep learning models on large dataset takes a lot of time and resources, it is desired to construct a small synthetic dataset with which we can train deep learning models sufficiently. There are recent works that have explored…
We present a deep learning model to automatically generate computer models of the human heart from patient imaging data with an emphasis on its capability to generate thin-walled cardiac structures. Our method works by deforming a template…
Patient-specific cardiac modeling combines geometries of the heart derived from medical images and biophysical simulations to predict various aspects of cardiac function. However, generating simulation-suitable models of the heart from…
In applications such as molecule design or drug discovery, it is desirable to have an algorithm which recommends new candidate molecules based on the results of past tests. These molecules first need to be synthesized and then tested for…
Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…
Graph mining for structural patterns is a fundamental task in many applications. Compilation-based graph mining systems, represented by AutoMine, generate specialized algorithms for the provided patterns and substantially outperform other…
In this paper we propose and study a new complexity model for approximation algorithms. The main motivation are practical problems over large data sets that need to be solved many times for different scenarios, e.g., many multicast trees…
Imitation learning from a large set of human demonstrations has proved to be an effective paradigm for building capable robot agents. However, the demonstrations can be extremely costly and time-consuming to collect. We introduce MimicGen,…
The genome-scale metabolic model with protein constraint (PC-model) has been increasingly popular for microbial metabolic simulations. We present PROSO Toolbox, a unified and simple-to-use PC-model toolbox that takes any high-quality…
Let $V$ be a finite set of points in the plane. We present a 2-local algorithm that constructs a plane $\frac{4 \pi \sqrt{3}}{9}$-spanner of the unit-disk graph $\UDG(V)$. This algorithm makes only one round of communication and each point…
The repeat content and heterozygosity rate of a target genome are important factors in determining the feasibility of achieving a complete telomere-to-telomere assembly. The mathematical relationship between the required coverage and read…
Dual-species single-atom array in optical tweezers has several advantages over the single-species atom array as a platform for quantum computing and quantum simulation. Thus, creating the defect-free dual-species single-atom array with atom…
Graph kernels are often used in bioinformatics and network applications to measure the similarity between graphs; therefore, they may be used to construct efficient graph classifiers. Many graph kernels have been developed thus far, but to…
Quantifying how hard it is to build a molecular graph matters for biosignature detection, chemical complexity, and cheminformatics. We present an exact, scalable algorithm to compute the molecular assembly index (MA) which prioritizes the…
In order to associate complex traits with genetic polymorphisms, genome-wide association studies process huge datasets involving tens of thousands of individuals genotyped for millions of polymorphisms. When handling these datasets, which…
In order to support the real-time interaction with LLMs and the instant search or the instant recommendation on social media, it becomes an imminent problem to build a k-NN graph or an indexing graph for the massive number of vectorized…
Binary time series data are very common in many applications, and are typically modelled independently via a Bernoulli process with a single probability of success. However, the probability of a success can be dependent on the outcome…
We consider the enumeration of maximal bipartite cliques (bicliques) from a large graph, a task central to many practical data mining problems in social network analysis and bioinformatics. We present novel parallel algorithms for the…