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Prediction of poly(lactic co glycolic acid) (PLGA) micro- and nanoparticles' dissolution rates plays a significant role in pharmaceutical and medical industries. The prediction of PLGA dissolution rate is crucial for drug manufacturing.…

Quantitative Methods · Quantitative Biology 2017-05-22 Varun Kumar Ojha , Konrad Jackowski , Ajith Abraham , Václav Snášel

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Machine Learning · Statistics 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

One of the central issues of several machine learning applications on real data is the choice of the input features. Ideally, the designer should select only the relevant, non-redundant features to preserve the complete information…

Machine Learning · Computer Science 2023-03-28 Paolo Bonetti , Alberto Maria Metelli , Marcello Restelli

In recent years, many design automation methods have been developed to routinely create approximate implementations of circuits and programs that show excellent trade-offs between the quality of output and required resources. This paper…

Neural and Evolutionary Computing · Computer Science 2021-08-17 Lukas Sekanina

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

The implementation of adaptive genetic algorithms (AGA) for optimization problems has proven to be superior than many other methods due to its nature of producing more robust and high quality solutions. Considering the complexity involved…

Computational Physics · Physics 2024-11-28 Brandon Willnecker , Mervlyn Moodley

Developing interpretable machine learning models has become an increasingly important issue. One way in which data scientists have been able to develop interpretable models has been to use dimension reduction techniques. In this paper, we…

Machine Learning · Computer Science 2023-03-23 Sean H. Merritt , Alexander P. Christensen

We present a Python package together with a practical guide for the implementation of a lightweight diversity-enhanced genetic algorithm (GA) approach for the exploration of multi-dimensional parameter spaces. Searching a parameter space…

Neural and Evolutionary Computing · Computer Science 2024-12-24 Jonas Wessén , Eliel Camargo-Molina

Principal Component Analysis (PCA) is the workhorse tool for dimensionality reduction in this era of big data. While often overlooked, the purpose of PCA is not only to reduce data dimensionality, but also to yield features that are…

Machine Learning · Computer Science 2021-11-30 Arpita Gang , Waheed U. Bajwa

The MaxCut problem is a fundamental problem in Combinatorial Optimization, with significant implications across diverse domains such as logistics, network design, and statistical physics. The algorithm represents innovative approaches that…

Quantum Physics · Physics 2025-01-03 Paulo A. Viana , Fernando M. de Paula Neto

In this paper we introduce a new classification algorithm called Optimization of Distributions Differences (ODD). The algorithm aims to find a transformation from the feature space to a new space where the instances in the same class are as…

Machine Learning · Computer Science 2017-03-06 Mohammad Reza Bonyadi , Quang M. Tieng , David C. Reutens

There is a growing interest in automated neural architecture search (NAS) methods. They are employed to routinely deliver high-quality neural network architectures for various challenging data sets and reduce the designer's effort. The NAS…

Neural and Evolutionary Computing · Computer Science 2022-06-28 Michal Pinos , Vojtech Mrazek , Lukas Sekanina

A Genetic Algorithm (GA) is proposed in which each member of the population can change schemata only with its neighbors according to a rule. The rule methodology and the neighborhood structure employ elements from the Cellular Automata (CA)…

Neural and Evolutionary Computing · Computer Science 2007-11-16 Vasileios Barmpoutis , Gary F. Dargush

In recent years microbiome studies have become increasingly prevalent and large-scale. Through high-throughput sequencing technologies and well-established analytical pipelines, relative abundance data of operational taxonomic units and…

Methodology · Statistics 2022-05-12 Yan Li , Gen Li , Kun Chen

For numerous reasons there raises a need for dimension reduction that preserves certain characteristics of data. In this work we focus on data coming from a mixture of Gaussian distributions and we propose a method that preserves…

Statistics Theory · Mathematics 2014-07-30 Ewa Nowakowska , Jacek Koronacki , Stan Lipovetsky

Statistical approaches that successfully combine multiple datasets are more powerful, efficient, and scientifically informative than separate analyses. To address variation architectures correctly and comprehensively for high-dimensional…

Methodology · Statistics 2023-09-01 Jiuzhou Wang , Eric F. Lock

High-dimensional big data appears in many research fields such as image recognition, biology and collaborative filtering. Often, the exploration of such data by classic algorithms is encountered with difficulties due to `curse of…

Machine Learning · Computer Science 2016-07-13 Amit Bermanis , Aviv Rotbart , Moshe Salhov , Amir Averbuch

This research developed a prototype data warehouse to integrate multi-source forestry data for long-term monitoring, management, and sustainability. The data warehouse is intended to accommodate all types of imagery from various platforms,…

Databases · Computer Science 2025-02-12 Kristina Cormier , Kongwen , Zhang , Joshua Padron-Uy , Albert Wong , Keona Gagnier , Ajitesh Parihar

Purpose: Handling heterogeneous and mixed data types has become increasingly critical with the exponential growth in real-world databases. While deep generative models attempt to merge diverse data views into a common latent space, they…

Machine Learning · Computer Science 2024-10-23 Alejandro Guerrero-López , Carlos Sevilla-Salcedo , Vanessa Gómez-Verdejo , Pablo M. Olmos

Extracting signals through alpha factor mining is a fundamental challenge in quantitative finance. Existing automated methods primarily follow two paradigms: Decoupled Factor Generation, which treats factor discovery as isolated events, and…

Artificial Intelligence · Computer Science 2026-02-13 Taian Guo , Haiyang Shen , Junyu Luo , Binqi Chen , Hongjun Ding , Jinsheng Huang , Luchen Liu , Yun Ma , Ming Zhang
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