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Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

Objective. Recent advancements in electrode designs and micro-fabrication technology has allowed existence of microelectrode arrays with hundreds of channels for single-cell recordings. In such electrophysiological recordings, each…

Understanding the function of complex cortical circuits requires the simultaneous recording of action potentials from many neurons in awake and behaving animals. Practically, this can be achieved by extracellularly recording from multiple…

Quantitative Methods · Quantitative Biology 2008-09-25 Ueli Rutishauser , Erin M. Schuman , Adam N. Mamelak

Spike sorting is a critical process for decoding large-scale neural activity from extracellular recordings. The advancement of neural probes facilitates the recording of a high number of neurons with an increase in channel counts, arising a…

Signal Processing · Electrical Eng. & Systems 2025-01-31 Yuntao Han , Yihan Pan , Xiongfei Jiang , Cristian Sestito , Shady Agwa , Themis Prodromakis , Shiwei Wang

Spikes can be easily detected inmostintracellular recordings as sharp peaks. However, insome experimental preparations,because of unipolar morphology or other characteristicsof the recorded neurons, the sizes of the spikes recorded from the…

Neurons and Cognition · Quantitative Biology 2021-11-23 Smith Gupta

Much of studies on neural computation are based on network models of static neurons that produce analog output, despite the fact that information processing in the brain is predominantly carried out by dynamic neurons that produce discrete…

Neurons and Cognition · Quantitative Biology 2017-06-21 Dongsung Huh , Terrence J. Sejnowski

Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data.…

Neurons and Cognition · Quantitative Biology 2019-01-15 Yuval Harel , Ron Meir , Manfred Opper

Spiking Neural Networks (SNN) are known to be very effective for neuromorphic processor implementations, achieving orders of magnitude improvements in energy efficiency and computational latency over traditional deep learning approaches.…

Neural and Evolutionary Computing · Computer Science 2022-07-15 Sidi Yaya Arnaud Yarga , Jean Rouat , Sean U. N. Wood

Spike sorting is essential for extracting neuronal information from neural signals and understanding brain function. With the advent of high-density microelectrode arrays (HDMEAs), the challenges and opportunities in multi-channel spike…

Signal Processing · Electrical Eng. & Systems 2024-12-30 Yuntao Han , Shiwei Wang , Alister Hamilton

In this paper authors have presented a power efficient scheme for implementing a spike sorting module. Spike sorting is an important application in the field of neural signal acquisition for implantable biomedical systems whose function is…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Anand Kumar Mukhopadhyay , Indrajit Chakrabarti , Arindam Basu , Mrigank Sharad

Extracellular recordings are transient voltage fluctuations in the vicinity of neurons, serving as a fundamental modality in neuroscience for decoding brain activity at single-neuron resolution. Spike sorting, the process of attributing…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Feng Cao , Zishuo Feng , Jicong Zhang , Wei Shi

In the last decade, there have been major advances in clusterless decoding algorithms for neural data analysis. These algorithms use the theory of marked point processes to describe the joint activity of many neurons simultaneously, without…

Neurons and Cognition · Quantitative Biology 2025-12-09 Azar Ghahari , Uri T. Eden

Characterising the representation of sensory stimuli in the brain is a fundamental scientific endeavor, which can illuminate principles of information coding. Most characterizations reduce the dimensionality of neural data by converting…

Neurons and Cognition · Quantitative Biology 2024-01-23 James B Isbister

The relationship between a neuron's complex inputs and its spiking output defines the neuron's coding strategy. This is frequently and effectively modeled phenomenologically by one or more linear filters that extract the components of the…

Neurons and Cognition · Quantitative Biology 2011-11-02 Michael Famulare , Adrienne L. Fairhall

Objective. Research on brain-computer interfaces (BCIs) is advancing towards rehabilitating severely disabled patients in the real world. Two key factors for successful decoding of user intentions are the size of implanted microelectrode…

Neurons and Cognition · Quantitative Biology 2023-04-05 Muhammad Saif-ur-Rehman , Omair Ali , Christian Klaes , Ioannis Iossifidis

We demonstrate the efficacy of a new spike-sorting method based on a Markov Chain Monte Carlo (MCMC) algorithm by applying it to real data recorded from Purkinje cells (PCs) in young rat cerebellar slices. This algorithm is unique in its…

Quantitative Methods · Quantitative Biology 2011-11-10 Matthieu Delescluse , Christophe Pouzat

Determining the positions of neurons in an extracellular recording is useful for investigating functional properties of the underlying neural circuitry. In this work, we present a Bayesian modelling approach for localizing the source of…

Neurons and Cognition · Quantitative Biology 2022-01-28 Cole L. Hurwitz , Kai Xu , Akash Srivastava , Alessio P. Buccino , Matthias H. Hennig

Objective. Spike sorting, a critical step in neural data processing, aims to classify spiking events from single electrode recordings based on different waveforms. This study aims to develop a novel online spike sorter, NeuSort, using…

Neural and Evolutionary Computing · Computer Science 2023-09-19 Hang Yu , Yu Qi , Gang Pan

We investigate the sparse functional identification of complex cells and the decoding of visual stimuli encoded by an ensemble of complex cells. The reconstruction algorithm of both temporal and spatio-temporal stimuli is formulated as a…

Neurons and Cognition · Quantitative Biology 2017-06-20 Aurel A. Lazar , Nikul H. Ukani , Yiyin Zhou

This paper introduces SpikeFit, a novel training method for Spiking Neural Networks (SNNs) that enables efficient inference on neuromorphic hardware, considering all its stringent requirements: the number of neurons and synapses that can…

Neural and Evolutionary Computing · Computer Science 2025-11-04 Ivan Kartashov , Mariia Pushkareva , Iakov Karandashev