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Related papers: Optimizing Real-Time Vaccine Allocation in a Stoch…

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The aim of this work is to investigate the optimal vaccine sharing between two SIR centers in the presence of migration fluxes of susceptibles and infected individuals during the mumps outbreak. Optimality of the vaccine allocation means…

Quantitative Methods · Quantitative Biology 2018-09-11 A. Chernov , M. Kelbert , A. Shemendyuk

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

Analysis of PDEs · Mathematics 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

To understand the impact of vaccination, we consider a SIVR (susceptible-infected-vaccinated-recovered) model which combines impulsive vaccination into the classical SIR model. The final size is firstly defined and estimated, and then the…

Populations and Evolution · Quantitative Biology 2024-10-29 Phyu Phyu Win , Zhigui Lin , Mengyun Zhang

Understanding the epidemic dynamics, and finding out efficient techniques to control it, is a challenging issue. A lot of research has been done on targeted immunization strategies, exploiting various global network topological properties.…

Social and Information Networks · Computer Science 2016-01-21 Naveen Gupta , Anurag Singh , Hocine Cherifi

We consider the spread of a supercritical stochastic SIR (Susceptible, Infectious, Recovered) epidemic on a configuration model random graph. We mainly focus on the final stages of a large outbreak and provide limit results for the duration…

Probability · Mathematics 2020-02-26 Abid Ali Lashari , Ana Serafimović , Pieter Trapman

In this work, to support decision making of immunisation strategies, we propose the inclusion of two vaccination doses in the SEIR model considering a stochastic cellular automaton. We analyse three different scenarios of vaccination: $i)…

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…

Dynamical Systems · Mathematics 2024-08-16 Yi Jiang , Kristin M. Kurianski , Jane HyoJin Lee , Yanping Ma , Daniel Cicala , Glenn Ledder

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

Populations and Evolution · Quantitative Biology 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri

The study of epidemiological systems has generated deep interest in exploring the dynamical complexity of common infectious diseases driven by seasonally varying contact rates. Mathematical modeling and field observations have shown that,…

Dynamical Systems · Mathematics 2021-12-22 Jorge Duarte , Cristina Januário , Nuno Martins , Jesús Seoane , Miguel AF Sanjuán

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

To mitigate the pandemic stemming from COVID-19, numerous nations have initiated extensive vaccination campaigns for their citizens since late 2020. While affluent countries have predominantly received vaccine allocations, fewer doses have…

Physics and Society · Physics 2024-04-01 Hsin-Ju Chou , Jing-Yuan Ko , Sung-Po Chao

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

Populations and Evolution · Quantitative Biology 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc