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Retrieving molecular structures from tandem mass spectra is a crucial step in rapid compound identification. Existing retrieval methods, such as traditional mass spectral library matching, suffer from limited spectral library coverage,…

Machine Learning · Computer Science 2025-11-11 Yiwen Zhang , Keyan Ding , Yihang Wu , Xiang Zhuang , Yi Yang , Qiang Zhang , Huajun Chen

Recently, entropic descriptors based the Monte Carlo hybrid reconstruction of the microstructure of a binary/greyscale pattern has been proposed (Piasecki 2011 Proc. R. Soc. A 467 806). We try to speed up this method applied in this…

Statistical Mechanics · Physics 2012-06-19 R. Piasecki , W. Olchawa

To perform uncertainty, sensitivity or optimization analysis on scalar variables calculated by a cpu time expensive computer code, a widely accepted methodology consists in first identifying the most influential uncertain inputs (by…

Statistics Theory · Mathematics 2013-05-28 Benjamin Auder , Agnes De Crecy , Bertrand Iooss , Michel Marques

Gradient porous structured materials possess significant potential of being applied in many engineering fields. To accelerate the design process of infill graded microstructures, a novel asymptotic homogenisation topology optimisation…

Computational Engineering, Finance, and Science · Computer Science 2019-12-18 Dingchuan Xue , Yichao Zhu , Shaoshuai Li , Chang Liu , Weisheng Zhang , Xu Guo

Scanning probe microscopy (SPM) investigations of on-surface chemistry on passivated silicon have only shown in-plane chemical reactions, and studies on bare silicon are limited in facilitating additional reactions…

Corporate credit underwriting requires analysts to extract actionable evidence from long, heterogeneous financial documents spanning hundreds of pages and multiple languages. Standard Retrieval-Augmented Generation (RAG) pipelines optimize…

Computation and Language · Computer Science 2026-05-21 Linus Ng Junjia , Ezekiel Tee Kongquan , Kelvin Heng , Kenneth Zhu Ke , Zhao Jing Yuan

The cellular composition of the tumor microenvironment can directly impact cancer progression and the efficacy of therapeutics. Understanding immune cell activity, the body's natural defense mechanism, in the vicinity of cancerous cells is…

Genomics · Quantitative Biology 2022-05-04 Cecily Wolfe , Yayi Feng , David Chen , Edwin Purcell , Anne Talkington , Sepideh Dolatshahi , Heman Shakeri

Recent developments for mathematical modeling and numerical simulation of biomolecular systems raise new demands for qualified, stable, and efficient surface meshing, especially in implicit-solvent modeling. In our former work, we have…

Numerical Analysis · Mathematics 2016-11-11 Tiantian Liu , Minxin Chen , Benzhuo Lu

The advent of highly accurate protein structure prediction methods has fueled an exponential expansion of the protein structure database. Consequently, there is a rising demand for rapid and precise structural homolog search. Traditional…

Biomolecules · Quantitative Biology 2023-12-01 Yuan Liu , Hong-Bin Shen

Graph-based representations such as Scene Graphs enable localization in structured indoor environments by matching a locally observed graph, constructed from sensor data, to a prior map. This process is particularly challenging in…

Retrieving procedure-oriented evidence from materials science papers is difficult because key synthesis details are often scattered across long, context-heavy documents and are not well captured by paragraph-only dense retrieval. We present…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Zhuoyu Wu , Wenhui Ou , Pei-Sze Tan , Wenqi Fang , Sailaja Rajanala , Raphaël C. -W. Phan

MPC (Magneto-Photonic Crystal) Optimisation is a feature-rich Windows software application designed to enable researchers to analyze the optical and magneto-optical spectral properties of multilayers containing gyrotropic constituents. A…

Applied Physics · Physics 2019-05-03 M. Vasiliev , K. Alameh , M. Nur-E-Alam

Large language models (LLMs) have recently achieved remarkable results in complex multi-step tasks, such as mathematical reasoning and agentic software engineering. However, they often struggle to maintain consistent performance across…

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

The main contribution of this paper, is to propose a novel semantic approach based on a Natural Language Processing technique in order to ensure a semantic unification of unstructured process patterns which are expressed not only in…

Artificial Intelligence · Computer Science 2012-10-03 Nahla Jlaiel , Khouloud Madhbouh , Mohamed Ben Ahmed

In this paper, we propose a multiscale empirical interpolation method for solving nonlinear multiscale partial differential equations. The proposed method combines empirical interpolation techniques and local multiscale methods, such as the…

Numerical Analysis · Mathematics 2014-07-02 Victor Calo , Yalchin Efendiev , Juan Galvis , Mehdi Ghommem

Virtual screening of small molecules against protein targets can accelerate drug discovery and development by predicting drug-target interactions (DTIs). However, structure-based methods like molecular docking are too slow to allow for…

Nowadays integration of mass matrix components in the element domain is performed using various numerical integration schemes, each one possess different level of accuracy, alters in number of integration (Gauss) points and requires…

Numerical Analysis · Mathematics 2014-10-14 Eli Hanukah

Vibrational spectroscopy is a cornerstone technique for molecular characterization and offers an ideal target for the computational investigation of molecular materials. Building on previous comprehensive assessments of efficient methods…

Structural Equation Modeling (SEM) is an umbrella term that includes numerous multivariate statistical techniques that are employed throughout a plethora of research areas, ranging from social to natural sciences. Until recently, SEM…

Applications · Statistics 2021-06-10 Georgy Meshcheryakov , Anna A. Igolkina , Maria G. Samsonova
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