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DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…

Quantum Physics · Physics 2020-05-22 Aritra Sarkar , Zaid Al-Ars , Carmen G. Almudever , Koen Bertels

Quantum computation promises significant computational advantages over classical computation for some problems. However, quantum hardware suffers from much higher error rates than in classical hardware. As a result, extensive quantum error…

The new field of quantum error correction has developed spectacularly since its origin less than two years ago. Encoded quantum information can be protected from errors that arise due to uncontrolled interactions with the environment.…

Quantum Physics · Physics 2009-10-30 John Preskill

Gene enhancers control when and where genes switch on, yet their sequence diversity and tissue specificity make them hard to pinpoint in colorectal cancer. We take a sequence-only route and fine-tune DNABERT-2, a transformer genomic…

Genomics · Quantitative Biology 2025-10-01 Darren King , Yaser Atlasi , Gholamreza Rafiee

Mitigation and calibration schemes are central to maximize the computational reach of today's Noisy Intermediate Scale Quantum (NISQ) hardware, but these schemes are often specialized to exclusively address either coherent or decoherent…

Quantum Physics · Physics 2024-06-19 Arnaud Carignan-Dugas , Shashank Kumar Ranu , Patrick Dreher

Due to its higher data density, longevity, energy efficiency, and ease of generating copies, DNA is considered a promising storage technology for satisfying future needs. However, a diverse set of errors including deletions, insertions,…

Information Theory · Computer Science 2022-08-05 Yuanyuan Tang , Shuche Wang , Hao Lou , Ryan Gabrys , Farzad Farnoud

We introduce an evolutionary algorithm called recombinator-$k$-means for optimizing the highly non-convex kmeans problem. Its defining feature is that its crossover step involves all the members of the current generation, stochastically…

Machine Learning · Computer Science 2022-02-10 Carlo Baldassi

Accurate decoding of quantum error-correcting codes is a crucial ingredient in protecting quantum information from decoherence. It requires characterizing the error channels corrupting the logical quantum state and providing this…

Quantum Physics · Physics 2025-04-28 Volodymyr Sivak , Michael Newman , Paul Klimov

Genomics is changing our understanding of humans, evolution, diseases, and medicines to name but a few. As sequencing technology is developed collecting DNA sequences takes less time thereby generating more genetic data every day. Today the…

Quantitative Methods · Quantitative Biology 2020-07-29 Sahand Salamat , Tajana Rosing

Resistive Random-Access Memory (ReRAM) crossbar arrays are promising candidates for in-situ matrix-vector multiplication (MVM), a frequent operation in Deep Learning algorithms. Despite their advantages, these emerging non-volatile memories…

Emerging Technologies · Computer Science 2024-12-05 Benyamin Khezeli , Hamid Reza Zarandi , Elham Cheshmikhani

The remarkable discovery of Quantum Error Correction (QEC), which can overcome the errors experienced by a bit of quantum information (qubit), was a critical advance that gives hope for eventually realizing practical quantum computers. In…

In order to achieve fault tolerance, highly reliable system often require the ability to detect errors as soon as they occur and prevent the speared of erroneous information throughout the system. Thus, the need for codes capable of…

Information Theory · Computer Science 2010-02-08 Muzhir Al-Ani , Qeethara Al-Shayea

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

Quantum hardware suffers from high error rates and noise, which makes directly running applications on them ineffective. Quantum Error Correction (QEC) is a critical technique towards fault tolerance which encodes the quantum information…

Quantum Physics · Physics 2024-04-24 Hanrui Wang , Pengyu Liu , Yilian Liu , Jiaqi Gu , Jonathan Baker , Frederic T. Chong , Song Han

Summary: We present a new tool to correct sequencing errors in Illumina data produced from high-coverage whole-genome shotgun resequencing. It uses a non-greedy algorithm and shows comparable performance and higher accuracy in an evaluation…

Genomics · Quantitative Biology 2015-02-13 Heng Li

Channel coding is vital for reliable sixth-generation (6G) data transmission, employing diverse error correction codes for various application scenarios. Traditional decoders require dedicated hardware for each code, leading to high…

Information Theory · Computer Science 2025-10-31 Yongli Yan , Jieao Zhu , Tianyue Zheng , Zhuo Xu , Chao Jiang , Linglong Dai

Quantum computers with hundreds of qubits will be available soon. Unfortunately, high device error-rates pose a significant challenge in using these near-term quantum systems to power real-world applications. Executing a program on existing…

Quantum Physics · Physics 2022-08-22 Swamit Tannu , Poulami Das , Ramin Ayanzadeh , Moinuddin Qureshi

Genome sequencing has become a central focus in computational biology. A genome study typically begins with sequencing, which produces millions to billions of short DNA fragments known as reads. Read mapping aligns these reads to a…

The advent of DNA and RNA sequencing has revolutionized the study of genomics and molecular biology. Next generation sequencing (NGS) technologies like Illumina, Ion Torrent, SOLiD sequencing etc. have brought about a quick and cheap way to…

Genomics · Quantitative Biology 2021-03-26 Yun Heo , Gowthami Manikandan , Anand Ramachandran , Deming Chen