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Time series models with recurrent neural networks (RNNs) can have high accuracy but are unfortunately difficult to interpret as a result of feature-interactions, temporal-interactions, and non-linear transformations. Interpretability is…

Machine Learning · Computer Science 2021-09-17 Asif Rahman , Yale Chang , Jonathan Rubin

Recurrent Neural Networks (RNNs), which are a powerful scheme for modeling temporal and sequential data need to capture long-term dependencies on datasets and represent them in hidden layers with a powerful model to capture more information…

Machine Learning · Computer Science 2017-06-08 Andros Tjandra , Sakriani Sakti , Ruli Manurung , Mirna Adriani , Satoshi Nakamura

Randomized controlled trials (RCTs) are the standard for evaluating the effectiveness of clinical interventions. To address the limitations of RCTs on real-world populations, we developed a methodology that uses a large observational…

Machine Learning · Computer Science 2024-10-21 Panayiotis Petousis , David Gordon , Susanne B. Nicholas , Alex A. T. Bui

With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data. Powered by Recurrent Neural Network (RNN) architectures with Long…

Machine Learning · Statistics 2018-07-17 Huan Song , Deepta Rajan , Jayaraman J. Thiagarajan , Andreas Spanias

The proliferation of large-scale and structurally complex data has spurred the integration of machine learning methods into statistical modeling. Recurrent neural networks (RNNs), a foundational class of models for time-dependent data, can…

Machine Learning · Statistics 2026-05-05 Yuxi Cai , Lan Li , Feiqing Huang , Guodong Li

Understanding the internal dynamics of Recurrent Neural Networks (RNNs) is crucial for advancing their interpretability and improving their design. This study introduces an innovative information-theoretic method to identify and analyze…

Machine Learning · Computer Science 2025-10-03 Arend Hintze , Asadullah Najam , Jory Schossau

Obesity is a serious public health concern world-wide, which increases the risk of many diseases, including hypertension, stroke, and type 2 diabetes. To tackle this problem, researchers across the health ecosystem are collecting diverse…

Machine Learning · Computer Science 2018-09-24 Qinghan Xue , Xiaoran Wang , Samuel Meehan , Jilong Kuang , Alex Gao , Mooi Choo Chuah

In this paper, we have used Recurrent Neural Networks to capture and model human motion data and generate motions by prediction of the next immediate data point at each time-step. Our RNN is armed with recently proposed Gated Recurrent…

Neural and Evolutionary Computing · Computer Science 2015-01-05 Mohammad Pezeshki

Recurrent Neural Networks (RNNs) continue to show outstanding performance in sequence modeling tasks. However, training RNNs on long sequences often face challenges like slow inference, vanishing gradients and difficulty in capturing long…

Artificial Intelligence · Computer Science 2018-02-06 Victor Campos , Brendan Jou , Xavier Giro-i-Nieto , Jordi Torres , Shih-Fu Chang

Recurrent neural networks (RNNs) are commonly applied to clinical time-series data with the goal of learning patient risk stratification models. Their effectiveness is due, in part, to their use of parameter sharing over time (i.e., cells…

Machine Learning · Computer Science 2020-01-03 Jeeheh Oh , Jiaxuan Wang , Shengpu Tang , Michael Sjoding , Jenna Wiens

Clinical medical data, especially in the intensive care unit (ICU), consist of multivariate time series of observations. For each patient visit (or episode), sensor data and lab test results are recorded in the patient's Electronic Health…

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Charles Elkan , Randall Wetzel

To be effective in sequential data processing, Recurrent Neural Networks (RNNs) are required to keep track of past events by creating memories. While the relation between memories and the network's hidden state dynamics was established over…

Machine Learning · Computer Science 2019-09-17 Doron Haviv , Alexander Rivkind , Omri Barak

In this paper, we introduce a novel architecture to connecting adaptive learning and neural networks into an arbitrary machine's control system paradigm. Two consecutive Recurrent Neural Networks (RNNs) are used together to accurately model…

Machine Learning · Computer Science 2020-02-26 Srikanth Chandar , Harsha Sunder

We have recently seen many successful applications of recurrent neural networks (RNNs) on electronic medical records (EMRs), which contain histories of patients' diagnoses, medications, and other various events, in order to predict the…

Machine Learning · Computer Science 2018-10-24 Bum Chul Kwon , Min-Je Choi , Joanne Taery Kim , Edward Choi , Young Bin Kim , Soonwook Kwon , Jimeng Sun , Jaegul Choo

Accuracy and interpretability are two dominant features of successful predictive models. Typically, a choice must be made in favor of complex black box models such as recurrent neural networks (RNN) for accuracy versus less accurate but…

Machine Learning · Computer Science 2017-02-28 Edward Choi , Mohammad Taha Bahadori , Joshua A. Kulas , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Recurrent neural networks (RNNs) were recently proposed for the session-based recommendation task. The models showed promising improvements over traditional recommendation approaches. In this work, we further study RNN-based models for…

Machine Learning · Computer Science 2016-09-19 Yong Kiam Tan , Xinxing Xu , Yong Liu

One of the major challenges for autonomous vehicles in urban environments is to understand and predict other road users' actions, in particular, pedestrians at the point of crossing. The common approach to solving this problem is to use the…

Computer Vision and Pattern Recognition · Computer Science 2020-05-15 Amir Rasouli , Iuliia Kotseruba , John K. Tsotsos

The medical community believes binary medical event outcomes in EHR data contain sufficient information for making a sensible recommendation. However, there are two challenges to effectively utilizing such data: (1) modeling the…

Artificial Intelligence · Computer Science 2024-09-12 Xihao Piao , Pei Gao , Zheng Chen , Lingwei Zhu , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Dynamic prediction of future clinical outcomes based on longitudinally measured predictors plays a crucial role in disease management and patient counseling, particularly when conventional static models are inadequate. Joint modeling of…

Methodology · Statistics 2025-07-30 Wenhao Li , Shikun Wang , Zhe Yin , Brad C. Astor , Wei Yang , Tom H. Greene , Liang Li

Recurrent neural networks (RNNs) are widely used in computational neuroscience and machine learning applications. In an RNN, each neuron computes its output as a nonlinear function of its integrated input. While the importance of RNNs,…

Neurons and Cognition · Quantitative Biology 2012-07-10 Sebastian Bitzer , Stefan J. Kiebel