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Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 William Consagra , Eardi Lila

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

Computational Geometry · Computer Science 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

Resting-state functional magnetic resonance imaging (rs-fMRI)-derived functional connectivity patterns have been extensively utilized to delineate global functional organization of the human brain in health, development, and…

Quantitative Methods · Quantitative Biology 2020-10-02 Li Xiao , Biao Cai , Gang Qu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

A standard approach in functional neuroimaging explores how a particular cognitive task activates a set of brain regions (one task-to-many regions mapping). Importantly though, the same neural system can be activated by inherently different…

Neurons and Cognition · Quantitative Biology 2016-03-23 Romy Lorenz , Ricardo Pio Monti , Ines R. Violante , Christoforos Anagnostopoulos , Aldo A. Faisal , Giovanni Montana , Robert Leech

Non-invasive methods to measure brain activity are important to understand cognitive processes in the human brain. A prominent example is functional magnetic resonance imaging (fMRI), which is a noisy measurement of a delayed signal that…

Neurons and Cognition · Quantitative Biology 2020-08-17 Hans-Christian Ruiz-Euler , Jose R. Ferreira Marques , Hilbert J. Kappen

Combining Functional MRI (fMRI) data across different subjects and datasets is crucial for many neuroscience tasks. Relying solely on shared anatomy for brain-to-brain mapping is inadequate. Existing functional transformation methods thus…

Neurons and Cognition · Quantitative Biology 2025-03-18 Navve Wasserman , Roman Beliy , Roy Urbach , Michal Irani

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min

High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D…

Image and Video Processing · Electrical Eng. & Systems 2024-03-20 Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Juan Eugenio Iglesias

In neuroimaging analysis, fMRI can well assess the function changes for brain diseases with no obvious structural lesions. To date, most deep-learning-based fMRI studies have employed functional connectivity (FC) as the basic feature for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Wei Dai , Ziyao Zhang , Lixia Tian , Shengyuan Yu , Shuhui Wang , Zhao Dong , Hairong Zheng

In functional MRI (fMRI), effective connectivity analysis aims at inferring the causal influences that brain regions exert on one another. A common method for this type of analysis is structural equation modeling (SEM). We here propose a…

Quantitative Methods · Quantitative Biology 2024-09-10 G. Marrelec , A. Giron

Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

Quantitative Methods · Quantitative Biology 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

Recent studies on analyzing dynamic brain connectivity rely on sliding-window analysis or time-varying coefficient models which are unable to capture both smooth and abrupt changes simultaneously. Emerging evidence suggests state-related…

Applications · Statistics 2019-07-04 Chee-Ming Ting , Hernando Ombao , S. Balqis Samdin , Sh-Hussain Salleh

Whole-brain computational modeling based on structural connectivity has shown great promise in successfully simulating fMRI BOLD signals with temporal co-activation patterns that are highly similar to empirical functional connectivity…

Neurons and Cognition · Quantitative Biology 2019-11-14 Neda Kaboodvand , Martijn P van den Heuvel , Peter Fransson

Accurate segmentation of brain tissue in magnetic resonance images (MRI) is a diffcult task due to different types of brain abnormalities. Using information and features from multimodal MRI including T1, T1-weighted inversion recovery…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Yongpei Zhu , Zicong Zhou , Guojun Liao , Qianxi Yang , Kehong Yuan

High-resolution functional imaging is providing increasingly rich measurements of brain activity in animals and humans. A major challenge is to leverage such data to gain insight into the brain's computational mechanisms. The first step is…

Neurons and Cognition · Quantitative Biology 2016-08-09 Nikolaus Kriegeskorte , Jörn Diedrichsen

The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…

Neurons and Cognition · Quantitative Biology 2019-11-25 Elisa Ryyppö , Enrico Glerean , Elvira Brattico , Jari Saramäki , Onerva Korhonen

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

Statistics Theory · Mathematics 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart