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Photoacoustic computed tomography (PACT) is an emerging imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the photoacoustically induced initial pressure distribution within tissue. The…

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Photoacoustic tomography (PAT) is a non-invasive imaging modality that requires recovering the initial data of the wave equation from certain measurements of the solution outside the object. In the standard PAT measurement setup, the used…

Analysis of PDEs · Mathematics 2021-12-07 Linh V. Nguyen , Markus Haltmeier , Richard Kowar , Ngoc Do

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

Photoacoustic tomography (PAT) is a novel and promising technology in hybrid medical imaging that involves generating acoustic waves in the object of interest by stimulating electromagnetic energy. The acoustic wave is measured outside the…

Numerical Analysis · Mathematics 2022-08-24 Minam Moon , Injo Hur , Sunghwan Moon

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

We extend the forward-adjoint operator framework derived in our previous study to photoacoustic tomography (PAT). In that earlier work, the acoustic forward operator included a reception operator that maps, at each time step, the pressure…

Numerical Analysis · Mathematics 2026-05-06 Ashkan Javaherian

The photoacoustic tomography (PAT) is a hybrid modality that combines the optics and acoustics to obtain high resolution and high contrast imaging of heterogeneous media. In this work, our objective is to study the inverse problem in the…

Numerical Analysis · Mathematics 2021-05-26 Hongkai Zhao , Yimin Zhong

Iterative model-based image reconstruction in photoacoustic tomography (PAT) enables principled incorporation of detector physics, object-related priors, and complex acquisition strategies. However, for three-dimensional (3D) imaging…

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…

Medical Physics · Physics 2016-12-21 Yang Lou , Kun Wang , Alexander. A. Oraevsky , Mark. A. Anastasio

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

Quantitative Photoacoustic tomography (QPAT) is an emerging medical imaging modality which offers the possibility of combining the high resolution of the acoustic waves and large contrast of optical waves by quantifying the molecular…

Numerical Analysis · Mathematics 2014-10-30 Adriano De Cezaro , Fabiana Travessini De Cezaro

In this article, we revisit iterative methods for solving the inverse problem of photoacoustic tomography in free space. Recently, there have been interesting developments on explicit formulations of the adjoint operator, demonstrating that…

Analysis of PDEs · Mathematics 2017-05-16 Markus Haltmeier , Linh V. Nguyen
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