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Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

Structural identifiability analysis determines whether the parameters of a mechanistic ordinary differential equation (ODE) model can be uniquely recovered from ideal observations and is therefore a fundamental prerequisite for reliable…

Methodology · Statistics 2026-05-20 Abdallah Alsammani

What does it mean to say that a quantity is identifiable from the data? Statisticians seem to agree on a definition in the context of parametric statistical models --- roughly, a parameter $\theta$ in a model $\mathcal{P} = \{P_\theta:…

Methodology · Statistics 2020-02-17 Guillaume Basse , Iavor Bojinov

Linear non-Gaussian causal models postulate that each random variable is a linear function of parent variables and non-Gaussian exogenous error terms. We study identification of the linear coefficients when such models contain latent…

Methodology · Statistics 2026-03-05 Daniele Tramontano , Mathias Drton , Jalal Etesami

In this study, Bayesian inference is developed for structural vector autoregressive models in which the structural parameters are identified via Markov-switching heteroskedasticity. In such a model, restrictions that are just-identifying in…

Econometrics · Economics 2023-11-13 Helmut Lütkepohl , Tomasz Woźniak

In this paper, we consider the problem of local parameter identifiability of a parameter function in a system of ordinary differential equations. Previously, in this problem, the case where the dimensions of a parameter and a solution of a…

Dynamical Systems · Mathematics 2025-12-29 V. S. Shalgin

We study parameter identifiability of directed Gaussian graphical models with one latent variable. In the scenario we consider, the latent variable is a confounder that forms a source node of the graph and is a parent to all other nodes,…

Statistics Theory · Mathematics 2015-05-08 Dennis Leung , Mathias Drton , Hisayuki Hara

Online parameter identification is of importance, e.g., for model predictive control. Since the parameters have to be identified simultaneously to the process of the modeled system, dynamical update laws are used for state and parameter…

Numerical Analysis · Mathematics 2016-04-20 Romana Boiger , Barbara Kaltenbacher

Modelling, parameter identification, and simulation play an important role in systems biology. Usually, the goal is to determine parameter values that minimise the difference between experimental measurement values and model predictions in…

Mathematical Software · Computer Science 2013-04-10 Thomas Dierkes , Susanna Röblitz , Moritz Wade , Peter Deuflhard

Hierarchical Latent Attribute Models (HLAMs) are a family of discrete latent variable models that are attracting increasing attention in educational, psychological, and behavioral sciences. The key ingredients of an HLAM include a binary…

Machine Learning · Statistics 2021-10-11 Yuqi Gu , Gongjun Xu

This paper studies the problems of identifiability and estimation in high-dimensional nonparametric latent structure models. We introduce an identifiability theorem that generalizes existing conditions, establishing a unified framework…

Statistics Theory · Mathematics 2025-08-06 Yichen Lyu , Pengkun Yang

The problems of observability and identifiability have been of great interest as previous steps to estimating parameters and initial conditions of dynamical systems to which some known data (observations) are associated. While most works…

Dynamical Systems · Mathematics 2025-06-16 Alicja B Kubik , Benjamin Ivorra , Alain Rapaport , Ángel M Ramos

We summarize recent progress on the theory and applications of structural identifiability of compartmental models. On the applications side, we review identifiability analyses undertaken recently for models arising in epidemiology,…

Methodology · Statistics 2025-07-08 Nicolette Meshkat , Anne Shiu

This paper studies the role played by identification in the Bayesian analysis of statistical and econometric models. First, for unidentified models we demonstrate that there are situations where the introduction of a non-degenerate prior…

Econometrics · Economics 2021-10-20 Jean-Pierre Florens , Anna Simoni

Structural monitoring for complex built environments often suffers from mismatch between design, laboratory testing, and actual built parameters. Additionally, real-world structural identification problems encounter many challenges. For…

Machine Learning · Computer Science 2022-08-29 Xuyang Li , Hamed Bolandi , Talal Salem , Nizar Lajnef , Vishnu Naresh Boddeti

Effective application of mathematical models to interpret biological data and make accurate predictions often requires that model parameters are identifiable. Approaches to assess the so-called structural identifiability of models are…

Quantitative Methods · Quantitative Biology 2024-02-28 Alexander P Browning , Maria Tască , Carles Falcó , Ruth E Baker

Parameter estimation is of foundational importance for various model-based battery management tasks, including charging control, state-of-charge estimation and aging assessment. However, it remains a challenging issue as the existing…

Systems and Control · Electrical Eng. & Systems 2022-07-13 Ning Tian , Yebin Wang , Jian Chen , Huazhen Fang

The bifactor model and its extensions are multidimensional latent variable models, under which each item measures up to one subdimension on top of the primary dimension(s). Despite their wide applications to educational and psychological…

Statistics Theory · Mathematics 2020-12-23 Guanhua Fang , Xin Xu , Jinxin Guo , Zhiliang Ying , Susu Zhang

An important problem in biological modeling is choosing the right model. Given experimental data, one is supposed to find the best mathematical representation to describe the real-world phenomena. However, there may not be a unique model…

Dynamical Systems · Mathematics 2024-07-03 Cashous Bortner , Nicolette Meshkat

Models for complex systems are often built with more parameters than can be uniquely identified by available data. Because of the variety of causes, identifying a lack of parameter identifiability typically requires mathematical…

Methodology · Statistics 2013-10-03 David Campbell , Subhash Lele
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