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Recent advances in large language models (LLMs) and biomedical foundation models (BioFMs) have achieved strong results in biological text reasoning, molecular modeling, and single-cell analysis, yet they remain siloed in disjoint embedding…

Quantitative Methods · Quantitative Biology 2025-10-03 Ching-Huei Tsou , Michal Ozery-Flato , Ella Barkan , Diwakar Mahajan , Ben Shapira

Relational and noSQL storages are developed for the fast processing of the large data sets having a stable structure, while the ontologies are used to rep-resent complex and dynamic sets of information of a limited size. In the in-dustrial…

Databases · Computer Science 2021-03-10 Sergey Gorshkov , Alexander Grebeshkov , Roman Shebalov

The number of linked data sources and the size of the linked open data graph keep growing every day. As a consequence, semantic RDF services are more and more confronted with various "big data" problems. Query processing in the presence of…

Databases · Computer Science 2015-10-13 Olivier Curé , Hubert Naacke , Tendry Randriamalala , Bernd Amann

Traditional retrieval methods have been essential for assessing document similarity but struggle with capturing semantic nuances. Despite advancements in latent semantic analysis (LSA) and deep learning, achieving comprehensive semantic…

Information Retrieval · Computer Science 2024-09-27 Solmaz Seyed Monir , Irene Lau , Shubing Yang , Dongfang Zhao

This paper studies the role that ontologies can play in establishing conceptual data models during the process of information systems development. A mapping algorithm has been proposed and embedded in a special purpose Transformation-Engine…

Software Engineering · Computer Science 2007-05-23 Haya El-Ghalayini , Mohammed Odeh , Richard McClatchey

Ontologies are known to improve the accuracy of Large Language Models (LLMs) when translating natural language queries into a formal query language like SQL or SPARQL. There are two ways to leverage ontologies when working with LLMs. One is…

Databases · Computer Science 2024-10-15 C. Civili , E. Sherkhonov , R. E. K. Stirewalt

As the number of scientific publications and preprints is growing exponentially, several attempts have been made to navigate this complex and increasingly detailed landscape. These have almost exclusively taken unsupervised approaches that…

Curating, processing, and combining large-scale medical imaging datasets from national studies is a non-trivial task due to the intense computation and data throughput required, variability of acquired data, and associated financial…

In recent years, data lakes emerged as away to manage large amounts of heterogeneous data for modern data analytics. One way to prevent data lakes from turning into inoperable data swamps is semantic data management. Some approaches propose…

Databases · Computer Science 2023-10-25 Sayed Hoseini , Johannes Theissen-Lipp , Christoph Quix

Data management applications are growing and require more attention, especially in the "big data" era. Thus, supporting such applications with novel and efficient algorithms that achieve higher performance is critical. Array database…

Databases · Computer Science 2025-02-04 Ahmed M. Abdelmoniem , Sameh Abdulah , Walid Atwa

There is a growing need to semantically process and integrate clinical data from different sources for clinical research. This paper presents an approach to integrate EHRs from heterogeneous resources and generate integrated data in…

The representation of workflows and processes is essential in materials science engineering, where experimental and computational reproducibility depend on structured and semantically coherent process models. Although numerous ontologies…

Information Retrieval · Computer Science 2025-09-30 Ebrahim Norouzi , Sven Hertling , Jörg Waitelonis , Harald Sack

Recently, there has been a growing interest in Multimodal Large Language Models (MLLMs) due to their remarkable potential in various tasks integrating different modalities, such as image and text, as well as applications such as image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Jihen Amara , Birgitta König-Ries , Sheeba Samuel

We introduce novel mathematical models and algorithms to generate (shortest or k different) explanations for biomedical queries, using answer set programming. We implement these algorithms and integrate them in BIOQUERY-ASP. We illustrate…

Artificial Intelligence · Computer Science 2020-02-19 Esra Erdem , Umut Oztok

Large ontologies still pose serious challenges to state-of-the-art ontology alignment systems. In the paper we present an approach that combines a lexical index, a neural embedding model and locality modules to effectively divide an input…

Artificial Intelligence · Computer Science 2018-06-01 Ernesto Jimenez-Ruiz , Asan Agibetov , Matthias Samwald , Valerie Cross

While classical planning languages make the closed-domain and closed-world assumption, there have been various approaches to extend those with DL reasoning, which is then interpreted under the usual open-world semantics. Current approaches…

Artificial Intelligence · Computer Science 2023-08-17 Tobias John , Patrick Koopmann

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

Machine Learning · Computer Science 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

While coreference resolution is traditionally used as a component in individual document understanding, in this work we take a more global view and explore what can we learn about a domain from the set of all document-level coreference…

Computation and Language · Computer Science 2024-10-23 Shir Ashury-Tahan , Amir David Nissan Cohen , Nadav Cohen , Yoram Louzoun , Yoav Goldberg

With the web getting bigger and assimilating knowledge about different concepts and domains, it is becoming very difficult for simple database driven applications to capture the data for a domain. Thus developers have come out with ontology…

Artificial Intelligence · Computer Science 2014-04-22 Iti Mathur , Nisheeth Joshi , Hemant Darbari , Ajai Kumar

Biomedical researchers use ontologies to annotate their data with ontology terms, enabling better data integration and interoperability. However, the number, variety and complexity of current biomedical ontologies make it cumbersome for…

Artificial Intelligence · Computer Science 2017-06-09 Marcos Martinez-Romero , Clement Jonquet , Martin J. O'Connor , John Graybeal , Alejandro Pazos , Mark A. Musen
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