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We apply a self-consistent and robust Bayesian statistical approach to determining the ages, distances, and ZAMS masses of 28 field DA white dwarfs with ages of approximately 4 to 8 Gyrs. Our technique requires only quality optical and…

Solar and Stellar Astrophysics · Physics 2016-02-19 Erin M. O'Malley , Ted von Hippel , David van Dyk

Estimation of molecular evolutionary divergence times requires models of rate change. These vary with regard to the assumption of what quantity is penalized. The possibilities considered are the rate of evolution, the log of the rate of…

Genomics · Quantitative Biology 2007-12-31 Peter J Waddell

Age-disaggregated health data is crucial for effective public health planning and monitoring. Monitoring under-five mortality, for example, requires highly detailed age data since the distribution of potential causes of death varies…

Applications · Statistics 2023-02-23 Shuxian Fan , Li Liu , Jamie Perin , Tyler H. McCormick

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Metagenomics provides a powerful new tool set for investigating evolutionary interactions with the environment. However, an absence of model-based statistical methods means that researchers are often not able to make full use of this…

Quantitative Methods · Quantitative Biology 2013-06-27 John O'Brien , Xavier Didelot , Zamin Iqbal , LucasAmenga-Etego , Bartu Ahiska , Daniel Falush

The Bayesian method is noted to produce spuriously high posterior probabilities for phylogenetic trees in analysis of large datasets, but the precise reasons for this over-confidence are unknown. In general, the performance of Bayesian…

Statistics Theory · Mathematics 2018-10-15 Ziheng Yang , Tianqi Zhu

Background: Continuous traits evolution of a group of taxa that are correlated through a phylogenetic tree is commonly modelled using parametric stochastic differential equations to represent deterministic change of trait through time,…

Populations and Evolution · Quantitative Biology 2026-04-03 Bayu Brahmantio , Krzysztof Bartoszek , Etka Yapar

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Background. Conventional phylogenetic clustering approaches rely on arbitrary cutpoints applied a posteriori to phylogenetic estimates. Although in practice, Bayesian and bootstrap-based clustering tend to lead to similar estimates, they…

Methodology · Statistics 2017-08-10 Luc Villandré , Aurélie Labbe , Bluma Brenner , Michel Roger , David A. Stephens

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

Bayesian inference is a popular and widely-used approach to infer phylogenies (evolutionary trees). However, despite decades of widespread application, it remains difficult to judge how well a given Bayesian Markov chain Monte Carlo (MCMC)…

Methodology · Statistics 2022-09-07 Andrew F. Magee , Michael D. Karcher , Frederick A. Matsen , Vladimir N. Minin

Phylogenetic comparative methods correct for shared evolutionary history among a set of non-independent organisms by modeling sample traits as arising from a diffusion process along on the branches of a possibly unknown history. To…

Applications · Statistics 2020-09-30 Paul Bastide , Lam Si Tung Ho , Guy Baele , Philippe Lemey , Marc A Suchard

Divergence time estimation is crucial to provide temporal signals for dating biologically important events, from species divergence to viral transmissions in space and time. With the advent of high-throughput sequencing, recent Bayesian…

Populations and Evolution · Quantitative Biology 2021-10-27 Xiang Ji , Alexander A. Fisher , Shuo Su , Jeffrey L. Thorne , Barney Potter , Philippe Lemey , Guy Baele , Marc A. Suchard

Phylogenetic trees are widely used to understand the evolutionary history of organisms. Tree shapes provide information about macroevolutionary processes. However, macroevolutionary models are unreliable for inferring the true processes…

Populations and Evolution · Quantitative Biology 2021-10-11 Albert Ch. Soewongsono , Barbara R. Holland , Małgorzata M. O'Reilly

Updated evolutionary and pulsational model predictions are combined in order to interpret the properties of Galactic Classical Cepheids in the Gaia Data Release 2. In particular, the location of the instability strip boundaries and the…

Solar and Stellar Astrophysics · Physics 2020-07-08 Giulia De Somma , Marcella Marconi , Santi Cassisi , Vincenzo Ripepi , Silvio Leccia , Roberto Molinaro , Ilaria Musella

We present an update of our on-going effort to improve the precision of white dwarf cosmochronology via careful analyses of white dwarf photometry in open clusters. To improve the precision of white dwarf and main sequence age analysis, we…

Astrophysics · Physics 2007-05-23 T. von Hippel , D. E. Winget , W. H. Jefferys , J. G. Scott

There are several tools available to infer phylogenetic trees, which depict the evolutionary relationships among biological entities such as viral and bacterial strains in infectious outbreaks, or cancerous cells in tumor progression trees.…

Data Structures and Algorithms · Computer Science 2023-12-22 António Pedro Branco , Cátia Vaz , Alexandre P. Francisco

Motivation: The construction of statistics for summarizing posterior samples returned by a Bayesian phylogenetic study has so far been hindered by the poor geometric insights available into the space of phylogenetic trees, and ad hoc…

Applications · Statistics 2014-10-13 Philipp Benner , Miroslav Bacak , Pierre-Yves Bourguignon

Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in both endemic diseases and disease outbreaks; such research can aid in development of appropriate interventions and in design of studies to…

Quantitative Methods · Quantitative Biology 2018-01-24 Hesam Montazeri , Susan Little , Niko Beerenwinkel , Victor DeGruttola

Rate variation among the sites of a molecular sequence is commonly found in applications of phylogenetic inference. Several approaches exist to account for this feature but they do not usually enable the investigator to pinpoint the sites…

Quantitative Methods · Quantitative Biology 2013-05-23 Elisa Loza-Reyes , Merrilee Hurn , Tony Robinson