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Nystr\"om approximation is a fast randomized method that rapidly solves kernel ridge regression (KRR) problems through sub-sampling the n-by-n empirical kernel matrix appearing in the objective function. However, the performance of such a…

Machine Learning · Statistics 2021-03-10 Yifan Chen , Yun Yang

Causal inference is essential for data-driven decision-making, as it aims to uncover causal relationships from observational data. However, identifying causality remains challenging due to the potential for confounding and the distinction…

Machine Learning · Statistics 2026-05-08 Tianyu Yang , Md. Noor-E-Alam

Regions in the genome that affect complex traits, quantitative trait loci (QTL), can be identified using statistical analysis of genetic and phenotypic data. When restricted maximum-likelihood (REML) models are used, the mapping procedure…

Quantitative Methods · Quantitative Biology 2008-02-11 Kateryna Mishchenko , Sverker Holmgren , Lars Ronnegard

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov…

Populations and Evolution · Quantitative Biology 2024-12-30 ChenRui Duan , Zelin Zang , Siyuan Li , Yongjie Xu , Stan Z. Li

Tree ensembles are flexible predictive models that can capture relevant variables and to some extent their interactions in a compact and interpretable manner. Most algorithms for obtaining tree ensembles are based on versions of boosting or…

Machine Learning · Statistics 2020-02-21 Gitesh Dawer , Yangzi Guo , Adrian Barbu

We introduce a new phylogenetic reconstruction algorithm which, unlike most previous rigorous inference techniques, does not rely on assumptions regarding the branch lengths or the depth of the tree. The algorithm returns a forest which is…

Populations and Evolution · Quantitative Biology 2011-09-30 Constantinos Daskalakis , Elchanan Mossel , Sebastien Roch

Predicting the ancestral sequences of a group of homologous sequences related by a phylogenetic tree has been the subject of many studies, and numerous methods have been proposed to this purpose. Theoretical results are available that show…

Populations and Evolution · Quantitative Biology 2013-09-05 Olivier Gascuel , Mike Steel

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2019-09-11 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

This paper addresses computational challenges in estimating Quantile Regression with Selection (QRS). The estimation of the parameters that model self-selection requires the estimation of the entire quantile process several times. Moreover,…

Econometrics · Economics 2024-02-27 Santiago Pereda-Fernández

Approximate Bayesian Computation has been successfully used in population genetics to bypass the calculation of the likelihood. These methods provide accurate estimates of the posterior distribution by comparing the observed dataset to a…

Decision trees are well-known due to their ease of interpretability. To improve accuracy, we need to grow deep trees or ensembles of trees. These are hard to interpret, offsetting their original benefits. Shapley values have recently become…

Machine Learning · Computer Science 2023-01-26 Peng Yu , Chao Xu , Albert Bifet , Jesse Read

Bayesian inference is now a leading technique for reconstructing phylogenetic trees from aligned sequence data. In this short note, we formally show that the maximum posterior tree topology provides a statistically consistent estimate of a…

Populations and Evolution · Quantitative Biology 2013-07-12 Mike Steel

In this paper, we study the parallel query complexity of reconstructing biological and digital phylogenetic trees from simple queries involving their nodes. This is motivated from computational biology, data protection, and computer…

Data Structures and Algorithms · Computer Science 2020-09-10 Ramtin Afshar , Michael T. Goodrich , Pedro Matias , Martha C. Osegueda

We consider the branch-length estimation problem on a bifurcating tree: a character evolves along the edges of a binary tree according to a two-state symmetric Markov process, and we seek to recover the edge transition probabilities from…

Computation · Statistics 2025-07-30 David Clancy , Hanbaek Lyu , Sebastien Roch

Even with the advent of more sophisticated, data-hungry methods, boosted decision trees remain extraordinarily successful for fast rigid object detection, achieving top accuracy on numerous datasets. While effective, most boosted detectors…

Computer Vision and Pattern Recognition · Computer Science 2014-11-05 Woonhyun Nam , Piotr Dollár , Joon Hee Han

'Tree-based' phylogenetic networks proposed by Francis and Steel have attracted much attention of theoretical biologists in the last few years. At the heart of the definitions of tree-based phylogenetic networks is the notion of 'support…

Combinatorics · Mathematics 2019-04-30 Momoko Hayamizu , Kazuhisa Makino

Segmenting tree structures is common in several image processing applications. In medical image analysis, reliable segmentations of airways, vessels, neurons and other tree structures can enable important clinical applications. We present a…

Computer Vision and Pattern Recognition · Computer Science 2017-08-08 Raghavendra Selvan , Jens Petersen , Jesper H. Pedersen , Marleen de Bruijne

A plethora of problems in AI, engineering and the sciences are naturally formalized as inference in discrete probabilistic models. Exact inference is often prohibitively expensive, as it may require evaluating the (unnormalized) target…

Machine Learning · Computer Science 2019-10-16 Lars Buesing , Nicolas Heess , Theophane Weber

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

We consider statistical inference in the density estimation model using a tree-based Bayesian approach, with Optional P\'olya trees as prior distribution. We derive near-optimal convergence rates for corresponding posterior distributions…

Statistics Theory · Mathematics 2021-10-12 Ismaël Castillo , Thibault Randrianarisoa