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Related papers: The physical origin of hydrophobic effects

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In our recent works, based on the structural studies on water and interfacial water (topmost water layer at the solute/water interface), hydration free energy is derived and utilized to investigate the physical origin of hydrophobic…

Chemical Physics · Physics 2018-11-14 Qiang Sun

We use appropriately defined short ranged reference models of liquid water to clarify the different roles local hydrogen bonding, van der Waals attractions, and long ranged electrostatic interactions play in the solvation and association of…

Statistical Mechanics · Physics 2015-02-20 Richard C. Remsing , John D. Weeks

The aversion of hydrophobic solutes for water drives diverse interactions and assemblies across materials science, biology and beyond. % Here, we review the theoretical, computational and experimental developments which underpin a…

Soft Condensed Matter · Physics 2022-10-05 Nicholas B. Rego , Amish J. Patel

A theoretical model for the effect of water hydrogen bonding on the thermodynamics of hydrophobic hydration is proposed as a combination of the classical density functional theory with the recently developed probabilistic approach to water…

Statistical Mechanics · Physics 2011-06-16 Yuri S. Djikaev

Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affect hydrophobic phenomena, we use molecular simulations and theory to study hydration of solutes at interfaces. The solutes range in size…

Soft Condensed Matter · Physics 2014-09-05 Amish J. Patel , Patrick Varilly , Sumanth N. Jamadagni , Hari Acharya , Shekhar Garde , David Chandler

Based on our recent study on physical origin of hydrophobic effects, this is applied to investigate the dependence of hydrophobic interactions on the solute size. As two same hydrophobic solutes are dissolved into water, the hydration free…

Soft Condensed Matter · Physics 2018-03-07 Qiang Sun

The interactions of a hydrophilic surface with water can significantly influence the characteristics of the liquid water interface. In this manuscript, we explore this influence by studying the molecular structure of liquid water at a…

Soft Condensed Matter · Physics 2022-09-19 Sucheol Shin , Adam P. Willard

Hydrophobic interactions provide driving forces for protein folding, membrane formation, and oil-water separation. Motivated by information theory, the poorly understood nonpolar solute interactions in water are investigated. A simple…

chem-ph · Physics 2008-02-03 G. Hummer , S. Garde , A. E. Garcia , A. Pohorille , L. R. Pratt

We present a probabilistic approach to water-water hydrogen bonding that allows one to obtain an analytic expression for the number of bonds per water molecule as a function of both its distance to a hydrophobic particle and hydrophobe…

Soft Condensed Matter · Physics 2013-03-20 Yuri S. Djikaev , Eli Ruckenstein

The hydrophobic interaction, often combined with the hydrophilic or ionic interactions, makes the behavior of aqueous solutions very rich and plays an important role in biological systems. Theoretical and computer simulation studies haven…

Soft Condensed Matter · Physics 2024-11-05 Hidefumi Naito , Tomonari Sumi , Kenichiro Koga

The hydrophobic effect (HE) is commonly associated with the demixing of oil and water at ambient conditions and plays the leading role in determining the structure and stability of biomolecular assembly in aqueous solutions. On the…

Statistical Mechanics · Physics 2012-02-07 Aljaz Godec , Franci Merzel

Based on recent studies on hydrophobic interactions, it is devoted to investigate the directional nature of hydrophobic interactions. It means that the hydrophobic interactions are dependent on the relative orientations as the solutes tend…

Soft Condensed Matter · Physics 2021-05-19 Qiang Sun

Hydrophobic interactions are central to biological self-assembly and soft matter organization, yet their microscopic origins remain debated. A key hallmark is the strengthening of attraction between hydrophobic solutes with increasing…

Soft Condensed Matter · Physics 2025-09-25 Nigel B. Wilding , Francesco Turci

A theoretical approach is developed to quantify hydrophobic hydration and interactions on a molecular scale, with the goal of gaining insight into the molecular origins of hydrophobic effects. The model is based on the fundamental relation…

Chemical Physics · Physics 2016-08-15 G. Hummer , S. Garde , A. E. García , M. E. Paulaitis , L. R. Pratt

Solvent plays an important role in the relative motion of nanoscopic bodies, and the study of such phenomena can help elucidate the mechanism of hydrophobic assembly, as well as the influence of solvent-mediated effects on in vivo motion in…

Statistical Mechanics · Physics 2011-12-12 Joseph A. Morrone , Jingyuan Li , B. J. Berne

A comprehensive, semi-quantitative model for the thermodynamics of hydrophobic solvation is presented. The model is based on a very simple premise suggested by the scaled particle theory and treats both solute and solvent molecules as hard…

Biological Physics · Physics 2007-05-23 Hong Qian

With molecular simulation for water and a tunable hydrophobic substrate, we apply the instantaneous interface construction [A. P. Willard and D. Chandler, J. Phys. Chem. B, 114, 1954 (2010)] to examine the similarity between a water-vapor…

Soft Condensed Matter · Physics 2015-01-21 Adam P. Willard , David Chandler

We investigate the curvature-dependence of water dynamics in the vicinity of hydrophobic spherical solutes using molecular dynamics simulations. For both, the lateral and perpendicular diffusivity as well as for H-bond kinetics of water in…

Soft Condensed Matter · Physics 2016-01-22 R. Gregor Weiß , Matthias Heyden , Joachim Dzubiella

While the interactions between water molecules are dominated by strongly directional hydrogen bonds (HBs), it was recently proposed that relatively weak, isotropic van der Waals (vdW) forces are essential for understanding the properties of…

Computational Physics · Physics 2016-07-07 Tobias Morawietz , Andreas Singraber , Christoph Dellago , Jörg Behler

Water near hydrophobic surfaces is like that at a liquid-vapor interface, where fluctuations in water density are substantially enhanced compared to that in bulk water. Here we use molecular simulations with specialized sampling techniques…

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