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Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic…

Populations and Evolution · Quantitative Biology 2010-05-10 Ryan N. Gutenkunst , Ryan D. Hernandez , Scott H. Williamson , Carlos D. Bustamante

In this paper we propose a Monte Carlo maximum likelihood estimation strategy for discretely observed Wright-Fisher diffusions. Our approach provides an unbiased estimator of the likelihood function and is based on exact simulation…

Statistics Theory · Mathematics 2024-06-11 Celia García-Pareja , Fabio Nobile

The large deviation principle is established for the Poisson--Dirichlet distribution when the parameter $\theta$ approaches infinity. The result is then used to study the asymptotic behavior of the homozygosity and the Poisson--Dirichlet…

Probability · Mathematics 2007-05-23 Donald A. Dawson , Shui Feng

The distribution of genetic polymorphisms in a population contains information about the mutation rate and the strength of natural selection at a locus. Here, we show that the Poisson Random Field (PRF) method of population-genetic…

Populations and Evolution · Quantitative Biology 2007-07-18 Michael M Desai , Joshua B. Plotkin

Evolutionary models for populations of constant size are frequently studied using the Moran model, the Wright-Fisher model, or their diffusion limits. When evolution is neutral, a random genealogy given through Kingman's coalescent is used…

Populations and Evolution · Quantitative Biology 2012-07-31 Peter Pfaffelhuber , Benedikt Vogt

Motivated by applications in medical bioinformatics, Khayatian et al. (2024) introduced a family of metrics on Cayley trees (the $k$-RF distance, for $k=0, \ldots, n-2$) and explored their distribution on pairs of random Cayley trees via…

Probability · Mathematics 2024-12-31 Michael Fuchs , Mike Steel

The stationary distribution of allele frequencies under a variety of Wright--Fisher $k$-allele models with selection and parent independent mutation is well studied. However, the statistical properties of maximum likelihood estimates of…

Applications · Statistics 2009-10-12 Erkan Ozge Buzbas , Paul Joyce

We consider the sensitivity, with respect to a parameter \theta, of parametric families of operators A_{\theta}, vectors \pi_{\theta} corresponding to the adjoints A_{\theta}^{*} of A_{\theta} via A_{\theta}^{*}\pi_{\theta}=0 and one…

Functional Analysis · Mathematics 2011-10-27 Peter Pfaffelhuber , Heinz Weisshaupt

Multitudinous probabilistic and combinatorial objects are associated with generating functions satisfying a composition scheme $F(z)=G(H(z))$. The analysis becomes challenging when this scheme is critical (i.e., $G$ and $H$ are…

Probability · Mathematics 2024-12-06 Cyril Banderier , Markus Kuba , Michael Wallner

Standard regression approaches assume that some finite number of the response distribution characteristics, such as location and scale, change as a (parametric or nonparametric) function of predictors. However, it is not always appropriate…

Methodology · Statistics 2020-07-14 Fernand A. Quintana , Peter Mueller , Alejandro Jara , Steven N. MacEachern

The current Poisson factor models often assume that the factors are unknown, which overlooks the explanatory potential of certain observable covariates. This study focuses on high dimensional settings, where the number of the count response…

Methodology · Statistics 2024-02-26 Wei Liu , Qingzhi Zhong

In this work we describe a new model for the evolution of a diploid structured population backwards in time that allows for large migrations and uneven offspring distributions. The model generalizes both the mean-field model of Birkner et…

Probability · Mathematics 2026-02-11 Maximillian Newman

We give a extensive account of a recent new way of applying the Dirichlet form theory to random Poisson measures. The main application is to obtain existence of density for thelaws of random functionals of L\'evy processes or solutions of…

Probability · Mathematics 2010-04-19 Nicolas Bouleau

Sweepstakes reproduction refers to a highly skewed individual recruitment success without involving natural selection and may apply to individuals in broadcast spawning populations characterised by Type III survivorship. We consider an…

Populations and Evolution · Quantitative Biology 2026-01-14 Jonathan A Chetwynd-Diggle , Bjarki Eldon

A framework for the mathematical modeling of evolution in group structured populations is introduced. The population is divided into a fixed large number of groups of fixed size. From generation to generation, new groups are formed that…

Populations and Evolution · Quantitative Biology 2011-06-24 Roberto H. Schonmann , Renato Vicente , Nestor Caticha

We investigate a nonlocal generalization of the Fisher-KPP equation, which incorporates logistic growth and diffusion, for a single species population in a viable patch (refuge). In this framework, diffusion plays an homogenizing role,…

Populations and Evolution · Quantitative Biology 2025-01-22 G. G. Piva , C. Anteneodo

We establish convergence to the Kingman coalescent for the genealogy of a geographically - or otherwise - structured version of the Wright-Fisher population model with fast migration. The new feature is that migration probabilities may…

Probability · Mathematics 2010-06-25 Serik Sagitov , Peter Jagers , Vladimir Vatutin

The Ricker model was introduced in the context of managing fishing stocks. It is a discrete non-linear iterative model given by $N(t+1)=rN(t)\exp(-N(t))$ where $N(t)$ is the population at time $t$. The model treated in this paper includes a…

Applications · Statistics 2017-03-08 Laurie Davies

Large sample size equivalence between the celebrated {\it approximated} Good-Turing estimator of the probability to discover a species already observed a certain number of times (Good, 1953) and the modern Bayesian nonparametric counterpart…

Statistics Theory · Mathematics 2019-01-29 Annalisa Cerquetti

We consider the Wright-Fisher model for a population of $N$ individuals, each identified with a sequence of a finite number of sites, and single-crossover recombination between them. We trace back the ancestry of single individuals from the…

Probability · Mathematics 2014-04-24 Ellen Baake , Ute von Wangenheim