English
Related papers

Related papers: RepEx: A Flexible Framework for Scalable Replica E…

200 papers

Targeting simulations on parallel hardware architectures, this paper presents computational kernels for efficient computations in mortar finite element methods. Mortar methods enable a variationally consistent imposition of coupling…

Numerical Analysis · Mathematics 2023-08-25 Matthias Mayr , Alexander Popp

Molecular dynamics (MD) simulations play a crucial role in resolving the underlying conformational dynamics of molecular systems. However, their capability to correctly reproduce and predict dynamics in agreement with experiments is limited…

Chemical Physics · Physics 2025-05-19 Ivan Gilardoni , Valerio Piomponi , Thorben Fröhlking , Giovanni Bussi

A modular, maintainable and extensible particle beam simulation architecture is presented. Design considerations for single particle, multi particle, and rms envelope simulations (in two and three dimensions) are outlined. Envelope…

Computational Physics · Physics 2007-05-23 Nicholas D. Pattengale , Christopher K. Allen

Simulation schemes that allow to change molecular representation in a subvolume of the simulation box while preserving the equilibrium with the surrounding introduce conceptual problems of thermodynamic consistency. In this work we present…

Statistical Mechanics · Physics 2010-03-31 Simon Poblete , Matej Praprotnik , Kurt Kremer , Luigi Delle Site

A comprehensive description of molecular electron transfer reactions is essential for our understanding of fundamental phenomena in bio-energetics and molecular electronics. Experimental studies of molecular systems in condensed-phase…

Quantum Physics · Physics 2021-02-04 Frank Schlawin , Manuel Gessner , Andreas Buchleitner , Tobias Schaetz , Spiros S Skourtis

Parallel tempering, also known as replica exchange sampling, is an important method for simulating complex systems. In this algorithm simulations are conducted in parallel at a series of temperatures, and the key feature of the algorithm is…

Probability · Mathematics 2012-06-14 Paul Dupuis , Yufei Liu , Nuria Plattner , J. D. Doll

Molecular relational learning (MRL) is crucial for understanding the interaction behaviors between molecular pairs, a critical aspect of drug discovery and development. However, the large feasible model space of MRL poses significant…

Machine Learning · Computer Science 2024-10-22 Sizhe Liu , Jun Xia , Lecheng Zhang , Yuchen Liu , Yue Liu , Wenjie Du , Zhangyang Gao , Bozhen Hu , Cheng Tan , Hongxin Xiang , Stan Z. Li

Over the recent years the importance of numerical experiments has gradually been more recognized. Nonetheless, sufficient documentation of how computational results have been obtained is often not available. Especially in the scientific…

Mathematical Software · Computer Science 2021-05-10 Jörg Fehr , Jan Heiland , Christian Himpe , Jens Saak

We show how accurate kinetic information, such as the rates of protein folding and unfolding, can be extracted from replica-exchange molecular dynamics (REMD) simulations. From the brief and continuous trajectory segments between replica…

Soft Condensed Matter · Physics 2009-10-23 Nicolae-Viorel Buchete , Gerhard Hummer

Scaling up executable code data is significant for improving language models' software engineering capability. The intricate nature of the process makes it labor-intensive, time-consuming and expert-knowledge-dependent to build a large…

Software Engineering · Computer Science 2025-10-21 Ruida Hu , Chao Peng , Xinchen Wang , Junjielong Xu , Cuiyun Gao

Quantum algorithms have the potential to revolutionize our understanding of open quantum systems in chemistry. In this work, we demonstrate that a repeated interaction model, which could serve as the foundation for a digital quantum…

Quantum Physics · Physics 2025-05-05 Lea K. Northcote , Matthew S. Teynor , Gemma C. Solomon

Achieving fault-tolerance will require a strong relationship between the hardware and the protocols used. Different approaches will therefore naturally have tailored proof-of-principle experiments to benchmark progress. Nevertheless,…

Quantum Physics · Physics 2024-05-28 Milan Liepelt , Tommaso Peduzzi , James R. Wootton

Computational experiments have become essential for scientific discovery, allowing researchers to test hypotheses, analyze complex datasets, and validate findings. However, as computational experiments grow in scale and complexity, ensuring…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-03 Eleni Adamidi , Panayiotis Deligiannis , Nikos Foutris , Thanasis Vergoulis

Understanding the complex behavior of molecular systems is fundamental to fields such as physics, materials science, and biology. Molecular dynamics (MD) simulations are crucial tools for studying atomic-level dynamics. This work focuses on…

Computational Engineering, Finance, and Science · Computer Science 2025-07-16 David Martin , Samuel James Newcome , Markus Mühlhäußer , Manish Kumar Mishra , Fabio Alexander Gratl , Hans-Joachim Bungartz

Context: The term reactivity is popular in two areas of research: programming languages and distributed systems. On one hand, reactive programming is a paradigm which provides programmers with the means to declaratively write event-driven…

Programming Languages · Computer Science 2019-02-05 Florian Myter , Christophe Scholliers , Wolfgang De Meuter

A combination of reaction-diffusion models with moving-boundary problems yields a system in which the diffusion (spreading and penetration) and reaction (transformation) evolve the system's state and geometry over time. These systems can be…

Computational Engineering, Finance, and Science · Computer Science 2020-08-26 Mojtaba Barzegari , Liesbet Geris

Context: It has been argued that software engineering replications are useful for verifying the results of previous experiments. However, it has not yet been agreed how to check whether the results hold across replications. Besides, some…

Software Engineering · Computer Science 2020-11-06 Adrian Santos , Sira Vegas , Markku Oivo , Natalia Juristo

Results of simulation studies evaluating the performance of statistical methods are often considered actionable and thus can have a major impact on the way empirical research is implemented. However, so far there is limited evidence about…

This paper introduces Recurrent Expansion (RE) as a new learning paradigm that advances beyond conventional Machine Learning (ML) and Deep Learning (DL). While DL focuses on learning from static data representations, RE proposes an…

Machine Learning · Computer Science 2025-07-15 Tarek Berghout

Network simulation plays a crucial role in both networking research and industry. Existing commonly-used Discrete Event Simulations (DES) are based on callback mechanisms for discrete event (DE). However, due to the inability of callbacks…

Networking and Internet Architecture · Computer Science 2026-05-19 Yuanyi Zhu , Zijian Li , Xin Ai , Zixuan Chen , Sen Liu , Yang Xu