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Spatial reaction-diffusion models have been employed to describe many emergent phenomena in biological systems. The modelling technique most commonly adopted in the literature implements systems of partial differential equations (PDEs),…

Quantitative Methods · Quantitative Biology 2015-10-05 Christian A. Yates , Mark B. Flegg

Interacting particle systems provide a fundamental framework for modeling collective behavior in biological, social, and physical systems. In many applications, stochastic perturbations are essential for capturing environmental variability…

Adaptation and Self-Organizing Systems · Physics 2026-02-04 Su Yang , Weiqi Chu , Panayotis G. Kevrekidis

Over the past decades, nonlocal models have been widely used to describe aggregation phenomena in biology, physics, engineering, and the social sciences. These are often derived as mean-field limits of attraction-repulsion agent-based…

Cell Behavior · Quantitative Biology 2025-05-14 Carles Falcó , Ruth E. Baker , José A. Carrillo

We consider a system of charged particles moving on the real line driven by electrostatic interactions. Since we consider charges of both signs, collisions might occur in finite time. Upon collision, some of the colliding particles are…

Analysis of PDEs · Mathematics 2022-07-01 Patrick van Meurs , Mark A. Peletier , Norbert Pozar

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

A variety of models for the membrane-mediated interaction of particles in lipid membranes, mostly well-established in theoretical physics, is reviewed from a mathematical perspective. We provide mathematically consistent formulations in a…

Analysis of PDEs · Mathematics 2016-06-29 Charles M. Elliott , Carsten Gräser , Graham Hobbs , Ralf Kornhuber , Maren-Wanda Wolf

Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during…

Soft Condensed Matter · Physics 2009-06-10 Thomas R. Weikl , Mesfin Asfaw , Heinrich Krobath , Bartosz Rozycki , Reinhard Lipowsky

In biomimetic and biological systems, interactions between surfaces are often mediated by adhesive molecules, nanoparticles, or colloids dispersed in the surrounding solution. We present here a general, statistical-mechanical model for two…

Soft Condensed Matter · Physics 2009-11-13 Bartosz Rozycki , Reinhard Lipowsky , Thomas R. Weikl

In this paper we consider an interacting particle system modeled as a system of $N$ stochastic differential equations driven by Brownian motions with a drift term including a confining potential acting on each particle, and an interaction…

Probability · Mathematics 2007-05-23 Matteo Ortisi

An improved linear model is developed for elasto-plastic and adhesive contact. New correlations are proposed and validated to estimate the key input parameters of the model, including contact stiffness, yield point, maximum pull-off force…

Fluid Dynamics · Physics 2022-07-19 Wenguang Nan , Wei Pin Goh , Mohammad Tarequr Rahman

We study a class of graphon particle systems with time-varying random coefficients. In a graphon particle system, the interactions among particles are characterized by the coupled mean field terms through an underlying graphon and the…

Systems and Control · Electrical Eng. & Systems 2025-10-02 Yan Chen , Tao Li , Xiaofeng Zong

This paper deals with the derivation of a collective model of cell populations out of an individual-based description of the underlying physical particle system. By looking at the spatial distribution of cells in terms of time-evolving…

Mathematical Physics · Physics 2014-11-12 Annachiara Colombi , Marco Scianna , Andrea Tosin

The aim of this paper is to study a PDE model for two diffusing species interacting by local size exclusion and global attraction. This leads to a nonlinear degenerate cross-diffusion system, for which we provide a global existence result.…

Analysis of PDEs · Mathematics 2017-03-21 Judith Berendsen , Martin Burger , Jan-Frederik Pietschmann

We consider a one-dimensional McKean-Vlasov SDE on a domain and the associated mean-field interacting particle system. The peculiarity of this system is the combination of the interaction, which keeps the average position prescribed, and…

Probability · Mathematics 2024-02-29 Michele Coghi , Wolfgang Dreyer , Paul Gajewski , Clemens Guhlke , Peter Friz , Mario Maurelli

We derive novel algorithms for optimization problems constrained by partial differential equations describing multiscale particle dynamics, including non-local integral terms representing interactions between particles. In particular, we…

Numerical Analysis · Mathematics 2021-09-09 Mildred Aduamoah , Benjamin D. Goddard , John W. Pearson , Jonna C. Roden

In this article, we consider a generalisation of the spatial Muller's ratchet introduced by Foutel-Rodier and Etheridge. This particle system is a spatial model of an asexual population, with birth and death rates that depend on the local…

Probability · Mathematics 2026-03-09 João Luiz de Oliveira Madeira , Marcel Ortgiese , Sarah Penington

Particle-mesh methods, such as the particle-in-cell (PIC) method, cannot retain exact pairwise interaction at sub-cell scales. For dense nonneutral relativistic electron bunches, this makes it difficult to accurately capture the…

Plasma Physics · Physics 2026-05-08 Yinjian Zhao , Yibo Liang , Yanan Zhang , Xiaochun Ma , Hui Liu

Cell proliferation and cell movement are fundamentally stochastic processes which lead to variability in the growth and spatial structure of cell populations in many biological settings, such as cell invasion, wound healing, and tumour…

Cell Behavior · Quantitative Biology 2026-04-23 John Carlo Dimaculangan , Cameron A. Smith , Christian A. Yates

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

In this paper we review several approaches to mathematical modeling of simple battery cells and develop these ideas further with emphasis on charge recovery and the response behavior of batteries to given external load. We focus on models…

Probability · Mathematics 2016-04-04 Ingemar Kaj , Victorien Konané
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