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We test the feasibility of calculating proton stopping power (SP) from a set of virtual monochromatic (VM) CT images, created with Monte Carlo-generated CT scans, using a dual-energy CT-to-SP procedure. The Monte Carlo CT simulations, with…

Medical Physics · Physics 2022-06-23 Adam Zieser , Ugur Akgun , Yasar Onel

Carbon-ion radiotherapy (CIRT) is generally evaluated with the dose weighted by relative biological effectiveness (RBE), while the radiation quality varying in the body of each patient is ignored for lack of such distribution. In this…

Medical Physics · Physics 2018-05-30 Nobuyuki Kanematsu , Naruhiro Matsufuji , Taku Inaniwa

In Europe the 20% of the CT scans cover the thoracic region. The acquired images contain information about the cardiovascular system that often remains latent due to the lack of contrast in the cardiac area. On the other hand, the contrast…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Gianmarco Santini , Lorena M. Zumbo , Nicola Martini , Gabriele Valvano , Andrea Leo , Andrea Ripoli , Francesco Avogliero , Dante Chiappino , Daniele Della Latta

We present improved fits to our treatment of suppression of dielectronic recombination at intermediate densities. At low densities, most recombined excited states eventually decay to the ground state, and therefore the total dielectronic…

Radiation Therapy (XRT) is one of the most common cancer treatment methods. In this paper, a new mathematical model is proposed for the population dynamics of heterogeneous tumor cells following external beam radiation treatment. According…

Quantitative Methods · Quantitative Biology 2018-01-23 Amin Oroji , Shantia Yarahmadian , Sarkhosh Seddighi , Mohd Omar

Dual-energy CT (DECT) has been increasingly used in imaging applications because of its capability for material differentiation. However, material decomposition suffers from magnified noise from two CT images of independent scans, leading…

Medical Physics · Physics 2019-06-19 Wenkun Zhang , Hanming Zhang , Linyuan Wang , Xiaohui Wang , Ailong Cai , Lei Li , Tianye Niu , Bin Yan

A 'dual-field' strategy is often used for tumors with highly complex shapes and/or with large volumes exceeding available field-size in both passive and scanning irradiations with ion beams. Range and setup uncertainties can cause hot and…

Medical Physics · Physics 2010-10-06 Taku Inaniwa , Nobuyuki Kanematsu , Takuji Furukawa , Koji Noda

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

The available experimental information on the Range-Energy relation for protons stopped in hydrogen gas is summarized in the SRIM software package. The estimated precision of this data is several percents. Here we describe a possibility to…

Instrumentation and Detectors · Physics 2019-12-13 A. Vorobyev , N. Sagidova

Dual energy computed tomography (DECT) has become of particular interest in clinic recent years. The DECT scan comprises two images, corresponding to two photon attenuation coefficients maps of the objects. Meanwhile, the DECT images are…

Medical Physics · Physics 2017-11-21 Sui Li , Yongbo Wang , Yuting Liao , Ji He , Dong Zeng , Zhaoying Bian , Jianhua Ma

The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…

Accelerator Physics · Physics 2025-06-25 Alexander A. Pryanichnikov , Dmitry Shwartz , Jon Feldmand , Joao Seco , Maria Francesca Spadea

It is possible to find the optimized radiation dose per session for a radiotherapy (RT) treatment, using a population dynamics model. This has already been done in a previous work for a protocol with 30 sessions and a fixed dose per…

Purpose: Variations in proton Relative Biological Effectiveness (RBE) with Linear Energy Transfer (LET) remain one of the largest sources of uncertainty in proton radiotherapy. This work seeks to identify physics-based metrics which can be…

Medical Physics · Physics 2018-12-05 Stephen J McMahon , Harald Paganetti , Kevin M Prise

Transport of fast electron in overdense plasmas is of key importance in high energy density physics. However, it is challenging to diagnose the fast electron transport in experiments. In this article, we study coherent transition radiation…

In this study, a machine learning-based technique is developed to reduce the computational cost required to explore large design spaces of substitutional alloys. The first advancement is based on a neural network approach to predict the…

Computational Physics · Physics 2020-04-03 Alhassan S. Yasin , Terence D. Musho

We have introduced a new method of estimating the electron temperature and density of H II regions by using single dish observations. In this method, multiple hydrogen radio recombination lines of different bands are computed under the…

Solar and Stellar Astrophysics · Physics 2019-11-14 F. -Y. Zhu , Q. -F. Zhu , J. -Z. Wang , J. -S Zhang

In radiotherapy, the internal movement of organs between treatment sessions causes errors in the final radiation dose delivery. Motion models can be used to simulate motion patterns and assess anatomical robustness before delivery.…

Technical Note describing studies, in 2011, of time resolved diode dosimetry in an anthropomorphic phantom at the Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, Boston, MA. This technique measures the water…

Medical Physics · Physics 2014-07-14 Bernard Gottschalk

The ion populations most frequently adopted for diagnostics in collisional plasmas are derived from the density independent, coronal approximation. In higher density, lower temperature conditions, ionisation rates are enhanced once…

Solar and Stellar Astrophysics · Physics 2020-07-22 R. P. Dufresne , G. Del Zanna , N. R. Badnell

We propose a multi-scale approach to understanding physics related to the ion/proton-beam cancer therapy and calculation of the probability of the DNA damage as a result of irradiation of patients with energetic (up to 430 MeV/u) ions. This…

Biological Physics · Physics 2009-11-13 A. V. Solov'yov , E. Surdutovich , E. Scifoni , I. Mishustin , W. Greiner
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