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This Letter studies the quasispecies dynamics of a population capable of genetic repair evolving on a time-dependent fitness landscape. We develop a model that considers an asexual population of single-stranded, conservatively replicating…

Populations and Evolution · Quantitative Biology 2009-11-13 Pavel Gorodetsky , Emmanuel Tannenbaum

While the use of spatial agent-based and individual-based models has flourished across many scientific disciplines, the complexities these models generate are often difficult to manage and quantify. This research reduces population-driven,…

Physics and Society · Physics 2021-08-24 John C. Stevenson

The behavior of interacting populations typically displays irregular temporal and spatial patterns that are difficult to reconcile with an underlying deterministic dynamics. A classical example is the heterogeneous distribution of plankton…

Populations and Evolution · Quantitative Biology 2009-11-13 M. H. Vainstein , J. M. Rubi , J. M. G. Vilar

Spatially extended population dynamics models that incorporate intrinsic noise serve as case studies for the role of fluctuations and correlations in biological systems. Including spatial structure and stochastic noise in predator-prey…

Statistical Mechanics · Physics 2018-01-09 Ulrich Dobramysl , Mauro Mobilia , Michel Pleimling , Uwe C. Täuber

The theory of life history evolution provides a powerful framework to understand the evolutionary dynamics of pathogens in both epidemic and endemic situations. This framework, however, relies on the assumption that pathogen populations are…

Populations and Evolution · Quantitative Biology 2017-11-28 Todd Parsons , Amaury Lambert , Troy Day , Sylvain Gandon

We discuss the population dynamics with selection and random diffusion, keeping the total population constant, in a fitness landscape associated with Constraint Satisfaction, a paradigm for difficult optimization problems. We obtain a phase…

Populations and Evolution · Quantitative Biology 2016-11-23 Tommaso Brotto , Guy Bunin , Jorge Kurchan

We investigate the time evolution and stationary states of a stochastic, spatially discrete, population model (contact process) with spatial heterogeneity and imposed drift (wind) in one- and two-dimensions. We consider in particular a…

Statistical Mechanics · Physics 2007-05-23 Jaewook Joo , Joel L. Lebowitz

Habitat fragmentation, often driven by human activities, alters ecological landscapes by disrupting connectivity and reshaping species interactions. In such fragmented environments, habitats can be modeled as networks, where individuals…

Populations and Evolution · Quantitative Biology 2025-11-07 James Austin Orgeron , Malbor Asllani

A macroscopic theory for describing cellular states during steady-growth is presented, which is based on the consistency between cellular growth and molecular replication, as well as the robustness of phenotypes against perturbations.…

Populations and Evolution · Quantitative Biology 2021-02-08 Kunihiko Kaneko , Chikara Furusawa

In contrast to the neutral population cycles of the deterministic mean-field Lotka--Volterra rate equations, including spatial structure and stochastic noise in models for predator-prey interactions yields complex spatio-temporal structures…

Populations and Evolution · Quantitative Biology 2013-10-16 Ulrich Dobramysl , Uwe C. Tauber

We consider integro-differential models describing the evolution of a population structured by a quantitative trait. Individuals interact competitively, creating a strong selection pressure on the population. On the other hand, mutations…

Analysis of PDEs · Mathematics 2012-03-20 Pierre-Emmanuel Jabin

Many mathematical models of evolution assume that all individuals experience the same environment. Here, we study the Moran process in heterogeneous environments. The population is of finite size with two competing types, which are exposed…

Populations and Evolution · Quantitative Biology 2018-12-19 Kamran Kaveh , Alex McAvoy , Martin A. Nowak

A tumor can be thought of as an ecosystem, which critically means that we cannot just consider it as a collection of mutated cells but more as a complex system of many interacting cellular and microenvironmental elements. At its simplest, a…

Populations and Evolution · Quantitative Biology 2013-05-03 Jill Gallaher , Alexander R. A. Anderson

Positive density-dependence occurs when individuals experience increased survivorship, growth, or reproduction with increased population densities. Mechanisms leading to these positive relationships include mate limitation, saturating…

Populations and Evolution · Quantitative Biology 2019-02-12 Sebastian J. Schreiber

We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which…

Populations and Evolution · Quantitative Biology 2015-06-16 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Stanislav Molchanov , Elena Zhizhina

Many biological systems regulate phenotypic heterogeneity as a fitness-maximising strategy in uncertain and dynamic environments. Analysis of such strategies is typically confined both to a discrete set of environmental conditions, and to a…

Populations and Evolution · Quantitative Biology 2025-07-02 Alexander P Browning , Sara Hamis

A population of heterogenous agents compeeting through a minority rule is investigated. Agents which frequently loose are selected for evolution by changing their strategies. The stationary composition of the population resulting for this…

Disordered Systems and Neural Networks · Physics 2009-10-31 Alexei Vazquez

Mathematical theory of selection is developed within the frameworks of general models of inhomogeneous populations with continuous time. Methods that allow us to study the distribution dynamics under natural selection and to construct…

Populations and Evolution · Quantitative Biology 2009-12-22 Georgy P. Karev

Phenotypic evolution implies sequential fixations of new genomic sequences. The speed at which these mutations fixate depends, in part, on the relative fitness (selection coefficient) of the mutant vs. the ancestor. Using a simple…

Populations and Evolution · Quantitative Biology 2014-02-04 Sorin Tanase-Nicola , Ilya Nemenman

Population-level scaling in ecological systems arises from individual growth and death with competitive constraints. We build on a minimal dynamical model of metabolic growth where the tension between individual growth and mortality…

Populations and Evolution · Quantitative Biology 2022-05-11 Edward D. Lee , Christopher P. Kempes , Geoffrey B. West
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