English
Related papers

Related papers: Embryo as an active granular fluid: stress-coordin…

200 papers

An adequate control of cell response in tissue engineering applications is of utmost importance to obtain products suitable to clinical practice. This paper is the first part of a series of two connected publications in which we study via…

Tissues and Organs · Quantitative Biology 2015-12-08 Chiara Lelli , Riccardo Sacco , Paola Causin , Manuela T. Raimondi

Actin filaments, crosslinkers and myosin molecular motors form contractile networks. For instance, the cell cortex is a thin network below the cell membrane ; contraction of the cell cortex allows cells to round up during cell division.…

It is now widely recognized that mechanical interactions between cells play a crucial role in epithelial morphogenesis, yet understanding the mechanisms through which stress and deformation affect cell behavior remains an open problem due…

Tissues and Organs · Quantitative Biology 2017-01-20 Nicholas Noll , Madhav Mani , Idse Heemskerk , Sebastian Streichan , Boris I. Shraiman

Understanding how biomechanical reorganization governs key biological processes, such as morphogenesis and development, requires predictive insights into stress distributions and cellular behavior. While traditional approaches focused on…

Biological Physics · Physics 2025-08-26 Tianxiang Ma , Valeriia Grudtsyna , Robin V. Bölsterli , Amin Doostmohammadi

The internal dynamics of active gels, both in artificial (in-vitro) model systems and inside the cytoskeleton of living cells, has been extensively studied by experiments of recent years. These dynamics are probed using tracer particles…

Soft Condensed Matter · Physics 2015-07-28 E. Ben Isaac , É. Fodor , P. Visco , F. van Wijland , N. S. Gov

The emergence of a body axis is a fundamental step in the development of multicellular organisms. In simple systems such as $\textit{Hydra}$, growing evidence suggests that mechanical forces generated by collective cellular activity play a…

Soft Condensed Matter · Physics 2026-01-09 Arthur Hernandez , Cuncheng Zhu , Luca Giomi

Collective cell migration is crucial to many physiological and pathological processes. Recent experimental studies have indicated that the active traction forces generated by migrating cells in fibrous extracellular matrix (ECM) can…

Soft Condensed Matter · Physics 2020-11-25 Yu Zheng , Qihui Fan , Christopher Eddy , Xiaochen Wang , Bo Sun , Fangfu Ye , Yang Jiao

Order and alignment are ubiquitous in growing colonies of rod-shaped bacteria due to the nematic properties of the constituent particles. These effects are the result of the active stresses generated by growth, passive mechanical…

Soft Condensed Matter · Physics 2022-07-07 Jonas Isensee , Lukas Hupe , Ramin Golestanian , Philip Bittihn

Coherent motions associated with extreme wall shear stress events are investigated for adverse pressure gradient turbulent boundary layers (APG-TBLs). The analyses are performed using wall-resolved large eddy simulations of a NACA0012…

Fluid Dynamics · Physics 2025-11-07 Leandro J. O. Silva , William R. Wolf

Mechanics has an important role during morphogenesis, both in the generation of forces driving cell shape changes and in determining the effective material properties of cells and tissues. Drosophila dorsal closure (DC) has emerged as a…

Contractile forces are essential for many developmental processes involving cell shape change and tissue deformation. Recent experiments on reconstituted actomyosin networks, the major component of the contractile machinery, have shown that…

Biological Physics · Physics 2012-05-31 Shenshen Wang , Peter G. Wolynes

Self-propelled particles possessing permanent magnetic dipole moments occur naturally in magnetotactic bacteria and in man-made systems like active colloids or micro-robots. Yet, the interplay between self-propulsion and anisotropic…

Soft Condensed Matter · Physics 2024-04-29 Maria Kelidou , Mohammad Fazelzadeh , Baptiste Parage , Sara Jabbari Farouji

The Drosophila melanogaster embryo, an elongated multi-nucleated cell, is a classical model system for eukaryotic development and morphogenesis. Recent work has shown that bulk cytoplasmic flows, driven by cortical contractions along the…

Fluid Dynamics · Physics 2023-10-20 Pyae Hein Htet , Eric Lauga

A continuum description is built to characterize the stationary and transient deformations of confluent tissues subject to heterogeneous activities. By defining a coarse-grained texture matrix field to represent the shape and size of cells,…

Biological Physics · Physics 2023-08-10 Fernanda Pérez-Verdugo , Rodrigo Soto

Eukaryotic flagella are active structures with a complex architecture of microtubules, motor proteins and elastic links. They are capable of whiplike motions driven by motors sliding along filaments that are themselves constrained at an…

Soft Condensed Matter · Physics 2012-11-22 Raghunath Chelakkot , Arvind Gopinath , L. Mahadevan , Michael F. Hagan

Active networks made of biopolymers and motor proteins are valuable bioinspired systems that have been used in the last decades to study the cytoskeleton and its self-organization under mechanical stimulation. Different techniques are…

Soft Condensed Matter · Physics 2023-05-15 Vahid Nasirimarekani , Olinka Ramìrez-Soto , Stefan Karpitschka , Isabella Guido

Phagocytosis is the process of engulfment and internalization of comparatively large particles by the cell, that plays a central role in the functioning of our immune system. We study the process of phagocytosis by considering a simplified…

Soft Condensed Matter · Physics 2022-01-05 Raj Kumar Sadhu , Sarah R Barger , Samo Penič , Aleš Iglič , Mira Krendel , Nils C Gauthier , Nir S Gov

Colloidal dispersions are prized as model systems to understand basic properties of materials, and are central to a wide range of industries from cosmetics to foods to agrichemicals. Among the key developments in using colloids to address…

Soft Condensed Matter · Physics 2022-06-22 Jun Dong , Francesco Turci , Robert L. Jack , Malcolm A. Faers , C. Patrick Royall

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

Biological Physics · Physics 2023-08-25 Mengyang Gu , Xinyi Fang , Yimin Luo

Viewed under a fluorescence microscope, the actomyosin cytoskeleton presents vivid streaks of lines together with persistent oscillatory waves. Using an active hydrodynamic approach, we show how a uniform distribution of single or mixture…

Soft Condensed Matter · Physics 2025-04-25 Ayan Roychowdhury , Saptarshi Dasgupta , Madan Rao