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A shortcoming of existing reachability approaches for nonlinear systems is the poor scalability with the number of continuous state variables. To mitigate this problem we present a simulation-based approach where we first sample a number of…

Systems and Control · Computer Science 2017-09-21 Murat Arcak , John Maidens

Model predictive control (MPC) is an optimization-based control strategy with broad industrial adoption. Unfortunately, the required computation time to solve the receding-horizon MPC optimization problem can become prohibitively large for…

Systems and Control · Electrical Eng. & Systems 2024-10-24 S. A. N. Nouwens , B. de Jager , M. M. Paulides , W. P. M. H. Heemels

We propose a sampling-based framework for finite-horizon trajectory and policy optimization under differentiable dynamics by casting controller design as inference. Specifically, we minimize a KL-regularized expected trajectory cost, which…

Machine Learning · Computer Science 2026-05-12 Heng Yang

Simulating the time evolution of a physical system at quantum mechanical levels of detail -- known as Hamiltonian Simulation (HS) -- is an important and interesting problem across physics and chemistry. For this task, algorithms that run on…

Molecular docking is a critical computational method in drug discovery used to predict the binding conformation and orientation of a ligand within a protein's binding site. Mapping this challenge onto a graph-based problem, specifically the…

Quantum Physics · Physics 2026-04-27 Mathieu Garrigues , Victor Onofre , Wesley Coelho , S. Acheche

Trajectories represent the mobility of moving objects and thus is of great value in data mining applications. However, trajectory data is enormous in volume, so it is expensive to store and process the raw data directly. Trajectories are…

Databases · Computer Science 2020-10-20 Yunheng Han , Hanan Samet

Machine-generated data is rapidly growing and poses challenges for data-intensive systems, especially as the growth of data outpaces the growth of storage space. To cope with the storage issue, compression plays a critical role in storage…

Databases · Computer Science 2023-11-27 Jiujing Zhang , Zhitao Shen , Shiyu Yang , Lingkai Meng , Chuan Xiao , Wei Jia , Yue Li , Qinhui Sun , Wenjie Zhang , Xuemin Lin

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Modern high-performance computing and Internet-of-Things deployments increasingly generate large volumes of signal data that must be compressed efficiently on resource-constrained acquisition devices and decompressed at scale on centralized…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-05 Ben Mechels , Ryan Billmeyer , Alexander Chen , Shiyang Li , Caiwen Ding

Reduced modeling of a computationally demanding dynamical system aims at approximating its trajectories, while optimizing the trade-off between accuracy and computational complexity. In this work, we propose to achieve such an approximation…

Machine Learning · Statistics 2025-02-20 Patrick Héas , Cédric Herzet , Benoit Combès

One of the most widely used samplers in practice is the component-wise Metropolis-Hastings (CMH) sampler that updates in turn the components of a vector valued Markov chain using accept-reject moves generated from a proposal distribution.…

Computation · Statistics 2017-03-22 Jinyoung Yang , Evgeny Levi , Radu V. Craiu , Jeffrey S. Rosenthal

Recurrent Neural Networks (RNNs) have been widely used in sequence analysis and modeling. However, when processing high-dimensional data, RNNs typically require very large model sizes, thereby bringing a series of deployment challenges.…

Machine Learning · Computer Science 2020-05-12 Miao Yin , Siyu Liao , Xiao-Yang Liu , Xiaodong Wang , Bo Yuan

SRAM-based cache memory faces several scalability limitations in deep nanoscale technologies, e.g., high leakage current, low cell stability, and low density. Emerging Non-Volatile Memory (NVM) technologies have received lots of attention…

Emerging Technologies · Computer Science 2025-12-02 Elham Cheshmikhani , Fateme Shokouhinia , Hamed Farbeh

Markov state models (MSMs) have been successful in computing metastable states, slow relaxation timescales and associated structural changes, and stationary or kinetic experimental observables of complex molecules from large amounts of…

Chemical Physics · Physics 2015-06-17 Frank Noe , Hao Wu , Jan-Hendrik Prinz , Nuria Plattner

The Hybrid Monte Carlo (HMC) algorithm currently is the favorite scheme to simulate quantum chromodynamics including dynamical fermions. In this talk-which is intended for a non-expert audience--I want to bring together methodical and…

High Energy Physics - Lattice · Physics 2009-10-30 Thomas Lippert

We describe a simple, efficient method for simulating Hamiltonian dynamics on a quantum computer by approximating the truncated Taylor series of the evolution operator. Our method can simulate the time evolution of a wide variety of…

Quantum Physics · Physics 2015-03-06 Dominic W. Berry , Andrew M. Childs , Richard Cleve , Robin Kothari , Rolando D. Somma

The accurate sampling of protein dynamics is an ongoing challenge despite the utilization of High-Performance Computers (HPC) systems. Utilizing only "brute force" MD simulations requires an unacceptably long time to solution. Adaptive…

Quantitative Methods · Quantitative Biology 2020-09-25 Eugen Hruska , Vivekanandan Balasubramanian , Hyungro Lee , Shantenu Jha , Cecilia Clementi

Recording of flash-ADC traces is challenging from both the transmission bandwidth and storage cost perspectives. This paper presents a configuration-free lossless compression algorithm which addresses both limitations, by compressing the…

Instrumentation and Detectors · Physics 2019-10-23 G. Bruni , H. T. Johansson

Covariance and histogram image descriptors provide an effective way to capture information about images. Both excel when used in combination with special purpose distance metrics. For covariance descriptors these metrics measure the…

Machine Learning · Statistics 2015-05-26 Matt J. Kusner , Nicholas I. Kolkin , Stephen Tyree , Kilian Q. Weinberger

This paper addresses the clustering of data in the hyperdimensional computing (HDC) domain. In prior work, an HDC-based clustering framework, referred to as HDCluster, has been proposed. However, the performance of the existing HDCluster is…

Machine Learning · Computer Science 2024-04-19 Lulu Ge , Keshab K. Parhi