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Related papers: Periodically driven DNA: Theory and simulation

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We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by…

Soft Condensed Matter · Physics 2009-11-07 Fei Liu , Luru Dai , Zhong-can Ou-Yang

We perform a detailed study of the dynamics of a nonlinear, one-dimensional oscillator driven by a periodic force under hysteretic damping, whose linear version was originally proposed and analyzed by Bishop in [1]. We first add a small…

Dynamical Systems · Mathematics 2020-05-14 Anastasios Bountis , Konstantinos Kaloudis , Christos Spitas

The complexity of the primary structure of human DNA is explored using methods from nonequilibrium statistical mechanics, dynamical systems theory and information theory. The use of chi-square tests shows that DNA cannot be described as a…

Genomics · Quantitative Biology 2015-06-17 A. Provata , C. Nicolis , G. Nicolis

We consider a class of parametrically forced Hamiltonian systems with one-and-a-half degrees of freedom and study the stability of the dynamics when the frequency of the forcing is relatively high or low. We show that, provided the…

Dynamical Systems · Mathematics 2017-03-07 M. Bartuccelli , G. Gentile , J. A. Wright

Storage and retrieval of the genetic information in cells is a dynamic process that requires the DNA to undergo dramatic structural rearrangements. DNA looping is a prominent example of such a structural rearrangement that is essential for…

Biological Physics · Physics 2015-01-07 Yi-Ju Chen , Stephanie Johnson , Peter Mulligan , Andrew J. Spakowitz , Rob Phillips

We introduce a coarse-grained rigid nucleotide model of DNA that reproduces the basic thermodynamics of short strands: duplex hybridization, single-stranded stacking and hairpin formation, and also captures the essential structural…

Soft Condensed Matter · Physics 2010-05-14 Thomas E. Ouldridge , Ard A. Louis , Jonathan P. K. Doye

Dynamical scaling analysis is theoretically performed for the ac (optical) Hall conductivity $\sigma_{xy}(\varepsilon_F,\omega)$ as a function of Fermi energy $\varepsilon_F$ and frequency $\omega$ for the two-dimensional electron gas and…

Mesoscale and Nanoscale Physics · Physics 2010-08-25 Takahiro Morimoto , Yshai Avishai , Hideo Aoki

We study the dynamics of an elastic chain driven on a disordered substrate and analyze numerically the statistics of force fluctuations at the depinning transition. The probability distribution function of the amplitude of the slip events…

Statistical Mechanics · Physics 2009-10-31 F. Lacombe , S. Zapperi , H. J. Herrmann

Force extension curves (FECs), which quantify the response of a variety of biomolecules subject to mechanical force ($f$), are often quantitatively fit using worm-like chain (WLC) or freely-jointed chain (FJC) models. These models predict…

Soft Condensed Matter · Physics 2015-06-05 Ngo Minh Toan , D. Thirumalai

DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a…

Soft Condensed Matter · Physics 2009-11-11 Paul A. Wiggins , Philip C. Nelson

We study numerically the phase diagram and the response under a driving force of the phase field crystal model for pinned lattice systems introduced recently for both one and two dimensional systems. The model describes the lattice system…

Materials Science · Physics 2009-09-30 C. V. Achim , J. A. P. Ramos , M. Karttunen , K. R. Elder , E. Granato , T. Ala-Nissila , S. C. Ying

Dynamics of a single stranded DNA, which can form a hairpin have been studied in the constant force ensemble. Using Langevin dynamics simulations, we obtained the force-temperature diagram, which differs from the theoretical prediction…

Soft Condensed Matter · Physics 2015-05-18 Garima Mishra , D. Giri , M. S. Li , S. Kumar

The importance of nonlinearities in material constitutive relations has long been appreciated in the continuum mechanics of macroscopic rods. Although the moment (torque) response to bending is almost universally linear for small deflection…

Soft Condensed Matter · Physics 2009-11-10 Paul A. Wiggins , Rob Phillips , Philip C. Nelson

Double-stranded DNA `overstretches' at a pulling force of about 65 pN, increasing in length by a factor of 1.7. The nature of the overstretched state is unknown, despite its considerable importance for DNA's biological function and…

Statistical Mechanics · Physics 2009-11-13 Stephen Whitelam , Sander Pronk , Phillip L. Geissler

Dynamos driven by rotating convection in the plane layer geometry are investigated numerically for a range of Ekman number ($E$), magnetic Prandtl number ($Pm$) and Rayleigh number ($Ra$). The primary purpose of the investigation is to…

Fluid Dynamics · Physics 2022-11-23 Ming Yan , Michael A. Calkins

We report translocation experiments on double-strand DNA through a silicon oxide nanopore. Samples containing DNA fragments with seven different lengths between 2000 to 96000 basepairs have been electrophoretically driven through a 10 nm…

Biomolecules · Quantitative Biology 2015-06-26 Arnold J. Storm , Cornelis Storm , Jianghua Chen , Henny Zandbergen , Jean-Francois Joanny , Cees Dekker

Single molecule experiments on B-DNA stretching have revealed one or two structural transitions, when increasing the external force. They are characterized by a sudden increase of DNA contour length and a decrease of the bending rigidity.…

Soft Condensed Matter · Physics 2012-10-25 Manoel Manghi , Nicolas Destainville , John Palmeri

Flexibility of short DNA helices is important for the biological functions such as nucleosome formation and DNA-protein recognition. Recent experiments suggest that short DNAs of tens of base pairs (bps) may have apparently higher…

Biological Physics · Physics 2015-06-24 Yuan-Yan Wu , Lei Bao , Xi Zhang , Zhi-Jie Tan

We study the conformation and dynamics of a single polymer chain that is pulled by a constant force applied at its one end with the other end free. Such a situation is relevant to the growing technology of manipulating individual…

Soft Condensed Matter · Physics 2015-06-04 Takahiro Sakaue , Takuya Saito , Hirofumi Wada

High-fidelity numerical simulations of compressible flow past a rapidly rotating cylinder are used to investigate the evolution of aerodynamic loads and flow instability over a wide range of Reynolds numbers (Re = 1000 to 6000). The study…

Fluid Dynamics · Physics 2026-05-27 Sanjeev Kumar , Santosh Kumar , Aditi Sengupta