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Cells are complex structures which require considerable amounts of organization via transport of large intracellular cargo. While passive diffusion is often sufficiently fast for the transport of smaller cargo, active transport is necessary…

Biomolecules · Quantitative Biology 2018-08-29 Robert Blackwell , David Jung , Mona Bukenberger , Ana-Sunčana Smith

Several experiments have demonstrated the existence of an electro-mechanical effect in many biological tissues and hydrogels, and its actual influence on growth, migration, and pattern formation. Here, to model these interactions and…

Soft Condensed Matter · Physics 2020-07-07 Yangkun Du , Yipin Su , Chaofeng Lu , Weiqiu Chen , Michel Destrade

We consider an optomechanical system comprising a single cavity mode and a dense spectrum of acoustic modes and solve for the quantum dynamics of initial cavity mode Fock (i.e., photon number) superposition states and thermal acoustic…

Quantum Physics · Physics 2021-12-16 Qidong Xu , M. P. Blencowe

The feedback between mechanical and chemical signals plays a key role in controlling many biological processes and collective cell behavior. Here we focus on the emergence of spatiotemporal density waves in a one-dimensional "cell train."…

Biological Physics · Physics 2025-02-12 Toshi Parmar , Liam P. Dow , Beth L. Pruitt , M. Cristina Marchetti

Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction…

A new model is suggested and used to mimic various spatial or temporal designs in biological or non biological formations where the focus is on the normal or irregular electrical signals coming from human heart (ECG) or brain (EEG). The…

Biological Physics · Physics 2008-07-08 Caglar Tuncay

High charge mobility in active layers of organic electronic devices is often necessary for their efficient operation. As a result, search for high-mobility materials among the plethora of synthesizable organic semiconductors is of paramount…

Mesoscale and Nanoscale Physics · Physics 2019-09-17 Andrey Yu. Sosorev

Torsional oscillator experiments show evidence of mass decoupling in solid 4He. This decoupling is amplitude dependent, suggesting a critical velocity for supersolidity. We observe similar behavior in the elastic shear modulus. By measuring…

Other Condensed Matter · Physics 2010-04-15 James Day , Oleksandr Syshchenko , John Beamish

Cell migration in fibreous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progression. During migration, individual cells can generate active…

Cell Behavior · Quantitative Biology 2019-10-16 Yu Zheng , Hanqing Nan , Qihui Fan , Xiaochen Wang , Liyu Liu , Ruchuan Liu , Fangfu Ye , Bo Sun , Yang Jiao

We use molecular dynamics simulations of a model three-dimensional particulate gel, to investigate the linear viscoelastic response. The numerical simulations are combined with a novel test protocol (the optimally- windowed chirp or OWCh),…

Soft Condensed Matter · Physics 2018-08-15 Mehdi Bouzid , Bavand Keshavarz , Michela Geri , Thibaut Divoux , Emanuela Del Gado , Gareth H. McKinley

There has been a long history in electrical muscle stimulation (EMS), which has been used for medical and interaction purposes. Human-computer interaction (HCI) researchers are now working on various applications, including virtual reality…

Human-Computer Interaction · Computer Science 2019-02-11 Michinari Kono , Jun Rekimoto

In this paper we introduce a new mathematical model for the active contraction of cardiac muscle, featuring different thermo-electric and nonlinear conductivity properties. The passive hyperelastic response of the tissue is described by an…

Tissues and Organs · Quantitative Biology 2019-05-02 Ricardo Ruiz Baier , Alessio Gizzi , Alessandro Loppini , Christian Cherubini , Simonetta Filippi

Organic mixed conductors (OMCs) represent a promising class of materials for applications in bioelectronics, physical computing, and thermoelectrics. Rather unparalleled, OMCs feature dynamics spanning multiple length and time scales,…

Disordered Systems and Neural Networks · Physics 2025-12-25 Lukas M. Bongartz

This work demonstrates preliminary results on energy harvesting from a linearly stable flutter-type system with circulatory friction forces. Harmonic external forcing is applied to study the energy flow in the steady sliding configuration.…

Applied Physics · Physics 2019-09-04 Merten Stender , Merten Tiedemann , Norbert Hoffmann

We use mesoscale numerical simulations to investigate the unsteady dynamics of a single red blood cell (RBC) subjected to an external mechanical load. We carry out a detailed comparison between the {\it loading} (L) dynamics, following the…

Soft Condensed Matter · Physics 2021-06-01 Fabio Guglietta , Marek Behr , Giacomo Falcucci , Mauro Sbragaglia

Object kinetic Montecarlo (OkMC) is a fundamental tool for modeling defect evolution in volumes and times far beyond atomistic models. The elastic interaction between defects is classically considered using a dipolar approximation but this…

Materials Science · Physics 2024-03-15 Rodrigo Santos-Güemes , Christophe J. Ortiz , Javier Segurado

Current scientific consensus holds that sound is transmitted, solely mechanically, from the tympanum to the cochlea via ossicles. But this theory does not explain the hearing extreme quality regarding high frequencies in mammals. So, we…

This paper first reviews the shoving model for the non-Arrhenius viscosity of viscous liquids. According to this model the main contribution to the activation energy of a flow event is the energy needed for molecules to shove aside the…

Soft Condensed Matter · Physics 2013-01-29 Jeppe C. Dyre , Tage Christensen , Niels Boye Olsen

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

Cell Behavior · Quantitative Biology 2019-07-08 Shou-Wen Wang , Lei-Han Tang

Current scientific consensus holds that sound is transmitted, solely mechanically, from the tympanum to the cochlea via ossicles. However this theory does not explain the hearing extreme quality regarding high frequencies in mammals. So, we…