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Homology has long been accepted as an important computable tool for quantifying complex structures. In many applications, these structures arise as nodal domains of real-valued functions and are therefore amenable only to a numerical study…

Probability · Mathematics 2020-05-29 Konstantin Mischaikow , Thomas Wanner

Topological data analysis is an emerging field that applies the study of topological invariants to data. Perhaps the simplest of these invariants is the number of connected components or clusters. In this work, we explore a topological…

Computational Geometry · Computer Science 2023-12-19 Ian Stewart Joyce , Grant Erdmann , Kirk P. Gardner , Ryan Kramer , Kyle Siegrist

An algorithm for the computation of global discrete conformal parametrizations with prescribed global holonomy signatures for triangle meshes was recently described in [Campen and Zorin 2017]. In this paper we provide a detailed analysis of…

Graphics · Computer Science 2017-05-09 Marcel Campen , Denis Zorin

In previous works [physics/0204035, physics/0404052, physics/0509126] a procedure was described for dividing the $3 \times N$-dimensional conformational space of a molecular system into a number of discrete cells, this partition allowed the…

Computational Physics · Physics 2008-12-14 Jacques Gabarro-Arpa

Linear binary fragmentation of synthetic fractal-like agglomerates composed of spherical, equal-size, touching monomers is numerically investigated. Agglomerates of different morphologies are fragmented via random bond removal. The…

Soft Condensed Matter · Physics 2019-09-27 Y. Drossinos , A. D. Melas , M. Kostoglou , L. Isella

We consider a refinement of the partition function of graph homomorphisms and present a quasi-polynomial algorithm to compute it in a certain domain. As a corollary, we obtain quasi-polynomial algorithms for computing partition functions…

Combinatorics · Mathematics 2015-08-04 Alexander Barvinok , Pablo Soberón

Motivated by the problem of domain formation in chromosomes, we studied a co--polymer model where only a subset of the monomers feel attractive interactions. These monomers are displaced randomly from a regularly-spaced pattern, thus…

Biomolecules · Quantitative Biology 2018-02-13 Matteo Negri , Marco Gherardi , Guido Tiana , Marco Cosentino Lagomarsino

Modern biological techniques such as Hi-C permit to measure probabilities that different chromosomal regions are close in space. These probabilities can be visualised as matrices called contact maps. In this paper, we introduce a…

Biomolecules · Quantitative Biology 2020-10-21 Simone Pigolotti , Mogens H. Jensen , Yinxiu Zhan , Guido Tiana

A clustering algorithm partitions a set of data points into smaller sets (clusters) such that each subset is more tightly packed than the whole. Many approaches to clustering translate the vector data into a graph with edges reflecting a…

Geometric Topology · Mathematics 2012-06-06 Jesse Johnson

A domain decomposition method for the solution of general variable-coefficient elliptic partial differential equations on regular domains is introduced. The method is based on tessellating the domain into overlapping thin slabs or shells,…

Numerical Analysis · Mathematics 2025-10-31 Simon Dirckx , Anna Yesypenko , Per-Gunnar Martinsson

Clustering algorithms became an essential part of the neurophysiological data analysis toolbox in the last twenty five years. Many problems, from the definition of cell types/groups based on morphological, molecular and physiological data…

Applications · Statistics 2025-09-23 Louise Martineau , Christophe Pouzat , Ségolen Geffray

The study of the sub-structure of complex networks is of major importance to relate topology and functionality. Many efforts have been devoted to the analysis of the modular structure of networks using the quality function known as…

Data Analysis, Statistics and Probability · Physics 2011-07-01 Belkacem Serrour , Alex Arenas , Sergio Gomez

A computational approach via implementation of the Principle Component Analysis (PCA) and Gaussian Mixture (GM) clustering methods from Machine Learning (ML) algorithms to identify domain structures of supercooled liquids is developed. Raw…

Statistical Mechanics · Physics 2022-03-24 Viet Nguyen , Xueyu Song

The huge amount of data acquired by high-throughput sequencing requires data reduction for effective analysis. Here we give a clustering algorithm for genome-wide open chromatin data using a new data reduction method. This method regards…

Genomics · Quantitative Biology 2024-10-14 Azusa Tanaka , Yasuhiro Ishitsuka , Hiroki Ohta , Akihiro Fujimoto , Jun-ichirou Yasunaga , Masao Matsuoka

In this paper, we provide new discrete uniformization theorems for bounded, $m$-connected planar domains. To this end, we consider a planar, bounded, $m$-connected domain $\Omega$ and let $\bord\Omega$ be its boundary. Let $\mathcal{T}$…

Geometric Topology · Mathematics 2013-12-24 Sa'ar Hersonsky

Chordal graphs can be used to encode dependency models that are representable by both directed acyclic and undirected graphs. This paper discusses a very simple and efficient algorithm to learn the chordal structure of a probabilistic model…

Machine Learning · Computer Science 2012-06-18 Vincent Auvray , Louis Wehenkel

We introduce a new self-consistent structure finding algorithm that parses large scale cosmological structure into clusters, filaments and voids. This structure finding algorithm probes the cosmological structure at multiple scales and…

Cosmology and Nongalactic Astrophysics · Physics 2016-05-04 Ali Snedden , Lara Arielle Phillips , Grant J. Mathews , Jared Coughlin , In-Saeng Suh , Aparna Bhattacharya

Analysis of higher-order organizations, usually small connected subgraphs called motifs, is a fundamental task on complex networks. This paper studies a new problem of testing higher-order clusterability: given query access to an undirected…

Data Structures and Algorithms · Computer Science 2023-10-09 Yifei Li , Donghua Yang , Jianzhong Li

We describe a new generation of algorithms capable of mapping the structure and conformations of macromolecules and their complexes from large ensembles of heterogeneous snapshots, and demonstrate the feasibility of determining both…

Biological Physics · Physics 2014-04-30 P. Schwander , R. Fung , A. Ourmazd

Order parameters based on spherical harmonics and Fourier coefficients already play a significant role in condensed matter research in the context of systems of spherical or point particles. Here, we extend these types of order parameter to…

Soft Condensed Matter · Physics 2010-12-22 Aaron S. Keys , Christopher R. Iacovella , Sharon C. Glotzer