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As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

Support vector machines and kernel methods are increasingly popular in genomics and computational biology, due to their good performance in real-world applications and strong modularity that makes them suitable to a wide range of problems,…

Quantitative Methods · Quantitative Biology 2007-05-23 Jean-Philippe Vert

We develop a simple and computationally efficient significance test for the features of a machine learning model. Our forward-selection approach applies to any model specification, learning task and variable type. The test is…

Machine Learning · Statistics 2019-10-15 Enguerrand Horel , Kay Giesecke

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all scientific…

Recent developments in next generation sequencing technology have led to the creation of extensive, open-source protein databases consisting of hundreds of millions of sequences. To render these sequences applicable in biomedical…

Machine Learning · Computer Science 2024-12-10 Azwad Tamir , Jiann-Shiun Yuan

Structured prediction plays a central role in machine learning applications from computational biology to computer vision. These models require significantly more computation than unstructured models, and, in many applications, algorithms…

Machine Learning · Computer Science 2013-12-03 Alexander Grubb , Daniel Munoz , J. Andrew Bagnell , Martial Hebert

Research organisms provide invaluable insights into human biology and diseases, serving as essential tools for functional experiments, disease modeling, and drug testing. However, evolutionary divergence between humans and research…

Genomics · Quantitative Biology 2025-11-05 Hao Yuan , Christopher A. Mancuso , Kayla Johnson , Ingo Braasch , Arjun Krishnan

Thanks to the increasing growth of computational power and data availability, the research in machine learning has advanced with tremendous rapidity. Nowadays, the majority of automatic decision making systems are based on data. However, it…

Machine Learning · Computer Science 2021-01-28 Elena Beretta , Antonio Vetrò , Bruno Lepri , Juan Carlos De Martin

This paper shows how information about the network's community structure can be used to define node features with high predictive power for classification tasks. To do so, we define a family of community-aware node features and investigate…

Social and Information Networks · Computer Science 2024-04-29 Bogumił Kamiński , Paweł Prałat , François Théberge , Sebastian Zając

Selective rationalization has become a common mechanism to ensure that predictive models reveal how they use any available features. The selection may be soft or hard, and identifies a subset of input features relevant for prediction. The…

Computation and Language · Computer Science 2019-12-17 Mo Yu , Shiyu Chang , Yang Zhang , Tommi S. Jaakkola

Social bookmarking and tagging has emerged a new era in user collaboration. Collaborative Tagging allows users to annotate content of their liking, which via the appropriate algorithms can render useful for the provision of product…

Social and Information Networks · Computer Science 2014-10-21 Georgios Pitsilis , Wei Wang

Software Categorization is the task of organizing software into groups that broadly describe the behavior of the software, such as "editors" or "science." Categorization plays an important role in several maintenance tasks, such as…

Software Engineering · Computer Science 2018-06-18 Alexander LeClair , Zachary Eberhart , Collin McMillan

Traditional fact checking by expert journalists cannot keep up with the enormous volume of information that is now generated online. Computational fact checking may significantly enhance our ability to evaluate the veracity of dubious…

Computers and Society · Computer Science 2020-07-01 Giovanni Luca Ciampaglia , Prashant Shiralkar , Luis M. Rocha , Johan Bollen , Filippo Menczer , Alessandro Flammini

Evaluating models on datasets often fails to capture their behavior when faced with unexpected and diverse types of inputs. It would be beneficial if we could evaluate the difference between human annotation and model prediction for an…

Machine Learning · Computer Science 2024-11-12 Weitang Liu , Ying Wai Li , Yuelei Li , Zihan Wang , Yi-Zhuang You , Jingbo Shang

Reproducibility is a key requirement for scientific progress. It allows the reproduction of the works of others, and, as a consequence, to fully trust the reported claims and results. In this work, we argue that, by facilitating…

Information Retrieval · Computer Science 2021-02-02 Alejandro Bellogín , Alan Said

This paper presents an automated approach for interpretable feature recommendation for solving signal data analytics problems. The method has been tested by performing experiments on datasets in the domain of prognostics where…

Machine Learning · Statistics 2017-11-07 Snehasis Banerjee , Tanushyam Chattopadhyay , Ayan Mukherjee

Pattern discovery algorithms in the music domain aim to find meaningful components in musical compositions. Over the years, although many algorithms have been developed for pattern discovery in music data, it remains a challenging task. To…

Sound · Computer Science 2020-10-26 Iris Ren , Anja Volk , Wouter Swierstra , Remco C. Veltkamp

In recent years, machine learning has been proposed as a promising strategy to build accurate scoring functions for computational docking finalized to numerically empowered drug discovery. However, the latest studies have suggested that…

Quantitative Methods · Quantitative Biology 2023-02-17 F. Pellicani , D. Dal Ben , A. Perali , S. Pilati

Citation recommendation is intended to assist researchers in the process of searching for relevant papers to cite by recommending appropriate citations for a given input text. Existing test collections for this task are noisy and unreliable…

Information Retrieval · Computer Science 2021-08-18 Florian Boudin