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Related papers: Systematic Measures of Biological Networks, Part I…

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This paper is Part I of a two-part series devoting to the study of systematic measures in a complex biological network modeled by a system of ordinary differential equations. As the mathematical complement to our previous work [31] with…

Probability · Mathematics 2016-06-13 Yao Li , Yingfei Yi

Just as a herd of animals relies on its robust social structure to survive in the wild, similarly robustness is a crucial characteristic for the survival of a complex network under attack. The capacity to measure robustness in complex…

Networking and Internet Architecture · Computer Science 2008-11-27 Ali Sydney , Caterina Scoglio , Phillip Schumm , Robert Kooij

The robustness of an ecological network quantifies the resilience of the ecosystem it represents to species loss. It corresponds to the proportion of species that are disconnected from the rest of the network when extinctions occur…

Populations and Evolution · Quantitative Biology 2021-11-25 Saint-Clair Chabert-Liddell , Pierre Barbillon , Sophie Donnet

Natural systems are remarkably robust and resilient, maintaining essential functions despite variability, uncertainty, and hostile conditions. Understanding these nonlinear, dynamic behaviours is challenging because such systems involve…

Mathematical Physics · Physics 2025-12-02 Daniele Proverbio , Rami Katz , Giulia Giordano

We introduce the concept of natural connectivity as a robustness measure of complex networks. The natural connectivity has a clear physical meaning and a simple mathematical formulation. It characterizes the redundancy of alternative paths…

Statistical Mechanics · Physics 2008-02-20 Jun Wu , Yue-Jin Tan , Hong-Zhong Deng , Yong Li , Bin Liu , Xin Lv

A full accounting of biological robustness remains elusive; both in terms of the mechanisms by which robustness is achieved and the forces that have caused robustness to grow over evolutionary time. Although its importance to topics such as…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James Whitacre , Axel Bender

A good deal of current research in complex networks involves the characterization and/or classification of the topological properties of given structures, which has motivated several respective measurements. This letter proposes a framework…

Physics and Society · Physics 2016-07-26 Cesar H. Comin , Filipi N. Silva , Luciano da F. Costa

The network approach became a widely used tool to understand the behaviour of complex systems in the last decade. We start from a short description of structural rigidity theory. A detailed account on the combinatorial rigidity analysis of…

Biological Physics · Physics 2012-12-04 Merse E. Gaspar , Peter Csermely

In this review, we give an introduction to the structural and functional properties of the biological networks. We focus on three major themes: topology of complex biological networks like the metabolic and protein-protein interaction…

Condensed Matter · Physics 2007-05-23 Indrani Bose

When a biological system robustly corrects component-level errors, the direct pressure on component performance declines. Components may become less reliable, maintain more genetic variability, or drift neutrally in design, creating the…

Populations and Evolution · Quantitative Biology 2023-12-27 Steven A. Frank

Ecological networks describe the interactions between different species, informing us of how they rely on one another for food, pollination and survival. If a species in an ecosystem is under threat of extinction, it can affect other…

Populations and Evolution · Quantitative Biology 2023-07-06 Chris Jones , Damaris Zurell , Karoline Wiesner

Robustness to genetic or environmental disturbances is often considered as a key property of living systems. Yet, in spite of being discussed since the 1950s, how robustness emerges from the complexity of genetic architectures and how it…

Populations and Evolution · Quantitative Biology 2022-03-31 Arnaud Le Rouzic

Here we propose a generic mechanism - networked buffering - for generating robust traits in complex systems that requires two basic conditions to be satisfied: 1) agents are versatile enough to perform more than one single functional role…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James M Whitacre , Axel Bender

Complex networks are ubiquitous: a cell, the human brain, a group of people and the Internet are all examples of interconnected many-body systems characterized by macroscopic properties that cannot be trivially deduced from those of their…

We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…

Molecular Networks · Quantitative Biology 2013-05-24 G. Menichetti , G. Bianconi , E. Giampieri , G. Castellani , D. Remondini

Networks effectively capture interactions among components of complex systems, and have thus become a mainstay in many scientific disciplines. Growing evidence, especially from biology, suggest that networks undergo changes over time, and…

Methodology · Statistics 2020-03-10 Ali Shojaie

Most complex systems are nonlinear, relying on emergent behavior from interacting subsystems, often characterized by oscillatory dynamics. Collective oscillatory behavior is essential for the proper functioning of many real world systems.…

Adaptation and Self-Organizing Systems · Physics 2024-07-03 Soumen Majhi , Biswambhar Rakshit , Amit Sharma , Jürgen Kurths , Dibakar Ghosh

The importance of studying properties of networks is manifest in diverse fields ranging from biology, engineering, physics, chemistry, neuroscience, and medicine. The functionality of networks with regard to performance, throughput,…

Molecular Networks · Quantitative Biology 2015-03-27 Allen Tannenbaum , Chris Sander , Liangjia Zhu , Romeil Sandhu , Ivan Kolesov , Eduard Reznik , Yasin Senbabaoglu , Tryphon Georgiou

Robustness, the insensitivity of some of a biological system's functionalities to a set of distinct conditions, is intimately linked to fitness. Recent studies suggest that it may also play a vital role in enabling the evolution of species.…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James M Whitacre , Axel Bender

In this work, water distribution systems are regarded as large sparse planar graphs with complex network characteristics and the relationship between important topological features of the network (i.e. structural robustness and loop…

Physics and Society · Physics 2010-09-23 A. Yazdani , P. Jeffrey
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