English
Related papers

Related papers: Actin automata with memory

200 papers

Actin is a globular protein which forms long filaments in the eukaryotic cytoskeleton, whose roles in cell function include structural support, contractile activity to intracellular signalling. We model actin filaments as two chains of…

Emerging Technologies · Computer Science 2015-06-22 Andrew Adamatzky , Richard Mayne

Actin is a globular protein which forms long polar filaments in the eukaryotic cytoskeleton. Actin networks play a key role in cell mechanics and cell motility. They have also been implicated in information transmission and processing,…

Emerging Technologies · Computer Science 2015-07-01 Stefano Siccardi , Jack A. Tuszynski , Andrew Adamatzky

We simulate an actin filament as an automaton network. Every atom takes two or three states and updates its state, in discrete time, depending on a ratio of its neighbours in some selected state. All atoms/automata simultaneously update…

Emerging Technologies · Computer Science 2018-07-18 Andrew Adamatzky

We represent a filamentous actin molecule as a graph of finite-state machines (F-actin automaton). Each node in the graph takes three states --- resting, excited, refractory. All nodes update their states simultaneously and by the same…

Emerging Technologies · Computer Science 2017-05-29 Andrew Adamatzky

Intermediate filaments form an essential structural network, spread throughout the cytoplasm and play a key role in cell mechanics, intracellular organization and molecular signaling. The maintenance of the network and its adaptation to the…

Subcellular Processes · Quantitative Biology 2023-06-14 Youngmin Park , Cécile Leduc , Sandrine Etienne-Manneville , Stéphanie Portet

The actin droplet machine is a computer model of a three-dimensional network of actin bundles developed in a droplet of a physiological solution, which implements mappings of sets of binary strings. The actin bundle network is conductive to…

Emerging Technologies · Computer Science 2019-05-21 Andrew Adamatzky , Florian Huber , Joerg Schnauss

Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over the course of the cell cycle, when cortical actin transitions…

Quantitative Methods · Quantitative Biology 2022-07-22 Maria-Veronica Ciocanel , Aravind Chandrasekaran , Carli Mager , Qin Ni , Garegin Papoian , Adriana Dawes

Actin is a filamentary protein which has many remarkable properties making it an ideal system for the study of the dynamics and mechanics of semi-flexible polymer solutions and gels; actin has a persistence length of over 10 microns and can…

Soft Condensed Matter · Physics 2008-02-03 A. C. Maggs

A \beta-skeleton is a proximity undirected graph whose connectivity is determined by the parameter \beta. We study \beta-skeleton automata where every node is a finite state machine taking two states, and updating its states depending on…

Emerging Technologies · Computer Science 2012-12-14 Ramon Alonso-Sanz , Andrew Adamatzky

Filamentous actin, a species of dynamic protein polymers, is one of the main components of the cytoskeleton of eukaryotic cells. We formulate a class of models that predict the possibility of bistable steady states in populations of dynamic…

Biomolecules · Quantitative Biology 2024-06-14 Panayiotis Foteinopoulos , Bela M. Mulder

Actin is a key component of the cytoskeleton, which plays central roles in cell motility, division, growth, and tensile strength. To enable this wide range of transient mechanical processes and properties, networks of actin filaments…

Commonly studied cellular automata are memoryless and have fixed topology of connections between cells. However by allowing updates of links and short-term memory in cells we may potentially discover novel complex regimes of spatio-temporal…

Cellular Automata and Lattice Gases · Physics 2012-12-13 Ramon Alonso-Sanz , Andrew Adamatzky

Computer simulations can aid in understanding how collective materials properties emerge from interactions between simple constituents. Here, we introduce a coarse-grained model that enables simulation of networks of actin filaments, myosin…

Biological Physics · Physics 2018-12-07 Simon L. Freedman , Shiladitya Banerjee , Glen M. Hocky , Aaron R. Dinner

The actin cortex is an active biopolymer network underneath the plasma membrane at the periphery of mammalian cells. It is a major regulator of cell shape through the generation of active cortical tension. In addition, the cortex…

Biological Physics · Physics 2023-05-15 Valentin Ruffine , Andreas Hartmann , Michael Schlierf , Elisabeth Fischer-Friedrich

The memristor is a device whose resistance changes depending on the polarity and magnitude of a voltage applied to the device's terminals. We design a minimalistic model of a regular network of memristors using structurally-dynamic cellular…

Cellular Automata and Lattice Gases · Physics 2015-06-03 Andrew Adamatzky , Leon Chua

The actin cortex is a thin layer of actin, myosin, and actin binding proteins that underlies the membrane of most animal cells. It is highly dynamic and can undergo remodelling on time-scales of tens of seconds thanks to protein turnover…

Cell Behavior · Quantitative Biology 2020-06-24 Manasi Kelkar , Pierre Bohec , Guillaume Charras

We study a discrete-time interacting particle system with continuous state space which is motivated by a mathematical model for turnover through branching in actin filament networks. It gives rise to transient clusters reminiscent of actin…

Probability · Mathematics 2024-10-01 Cecilia González-Tokman , Dietmar B. Oelz

Actin is one of the most studied cytoskeleton proteins showing a very rich span of structures. It can self-assemble actively into dynamical structures that govern the mechanical properties of the cell, its motility and its division.…

Soft Condensed Matter · Physics 2020-03-17 Maayan Levin , Raya Sorkin , David Pine , Rony Granek , Anne Bernheim-Groswasser , Yael Roichman

The actin cytoskeleton is a key component in the machinery of eukaryotic cells, and it selfassembles out of equilibrium into a wide variety of biologically crucial structures. While the molecular mechanisms involved are well characterized,…

Soft Condensed Matter · Physics 2017-01-04 Giulia Foffano , Nicolas Levernier , Martin Lenz

Cell polarization relies on long-range cortical flows, which are driven by active stresses and resisted by the cytoskeletal network. While the general mechanisms that contribute to cortical flows are known, a quantitative understanding of…

Soft Condensed Matter · Physics 2023-10-18 Yuqing Qiu , Elizabeth D. White , Edwin M. Munro , Suriyanarayanan Vaikuntanathan , Aaron R. Dinner
‹ Prev 1 2 3 10 Next ›