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In this paper we present a derivation and multiscale analysis of a mathematical model for plant cell wall biomechanics that takes into account both the microscopic structure of a cell wall coming from the cellulose microfibrils and the…

Analysis of PDEs · Mathematics 2016-01-01 Mariya Ptashnyk , Brian Seguin

In this paper homogenization of a mathematical model for plant tissue biomechanics is presented. The microscopic model constitutes a strongly coupled system of reaction-diffusion-convection equations for chemical processes in plant cells,…

Analysis of PDEs · Mathematics 2017-08-24 Andrey Piatnitski , Mariya Ptashnyk

In this paper homogenization of a mathematical model for biomechanics of a plant tissue with randomly distributed cells is considered. Mechanical properties of a plant tissue are modelled by a strongly coupled system of…

Analysis of PDEs · Mathematics 2020-10-28 Andrey Piatnitski , Mariya Ptashnyk

We carry out the homogenization of a fluid-structure interaction problem consisting in the periodic inclusions of a viscous fluid in an elastic body. We get a macrostructure model where the body behaves as a viscoelastic material with a…

Analysis of PDEs · Mathematics 2024-05-20 Juan Casado-Díaz

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

Biological Physics · Physics 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

It is known that the orientation of cellulose microfibrils within plant cell walls has an important impact on the morphogenesis of plant cells and tissues. Viewing the shape of a plant cell as a square prism or cylinder with the axis…

Cell Behavior · Quantitative Biology 2015-09-17 Mariya Ptashnyk , Brian Seguin

A non-local dynamic homogenization technique for the analysis of a viscoelastic heterogeneous material which displays a periodic microstructure is herein proposed. The asymptotic expansion of the micro-displacement field in the transformed…

Applied Physics · Physics 2018-11-26 Rosaria Del Toro , Andrea Bacigalupo , Marco Paggi

We study the coupling of a viscoelastic deformation governed by a Kelvin-Voigt model at equilibrium, based on the concept of second-grade nonsimple materials, with a plastic deformation due to volumetric swelling, described via a…

Analysis of PDEs · Mathematics 2024-09-12 Thomas Eiter , Leonie Schmeller

Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…

Biological Physics · Physics 2015-06-10 Jacob Notbohm , Ayelet Lesman , Phoebus Rosakis , David A. Tirrell , Guruswami Ravichandran

Vugs are small to medium-sized cavities inside rock, which have significant effects on the fluid flow in rock. Moreover, the presence of vugs may have non-trivial impacts on the geomechanical behavior of rock. How to quantify and analyze…

Computational Physics · Physics 2018-04-13 Zhaoqin Huang , Xu Zhou , Tao Huang , Jun Yao , Xiaoguang Wang , Hervé Jourde

Motivated by elastography that utilizes tissue mechanical properties as biomarkers for liver disease, with the eventual objective of quantitatively linking histopathology and bulk mechanical properties, we develop a micromechanical modeling…

Biological Physics · Physics 2025-01-06 Haritya Shah , Murthy N. Guddati

Tissue engineering aims to grow artificial tissues \emph{in vitro} to replace those in the body that have been damaged through age, trauma or disease. A recent approach to engineer artificial cartilage involves seeding cells within a…

Soft Condensed Matter · Physics 2017-12-05 M. J. Chen , L. S. Kimpton , J. P. Whiteley , M. Castilho , J. Malda , C. P. Please , S. L. Waters , H. M. Byrne

A micromorphic computational homogenization framework has recently been developed to deal with materials showing long-range correlated interactions, i.e. displaying patterning modes. Typical examples of such materials are elastomeric…

Soft Condensed Matter · Physics 2024-06-21 S. Maraghechi , O. Rokoš , R. H. J. Peerlings , M. G. D. Geers , J. P. M. Hoefnagels

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

For the first time the phenomenon of cellular structure coarsening are consistently analysed from the positions of kinetic, hydrodynamic and stochastodynamic theories of nonequilibrium statistical systems. Thereby micro-, meso- and…

Condensed Matter · Physics 2015-06-25 S. B. Goryachev

We construct a homogeneous, nonlinear elastic constitutive law, that models aspects of the mechanical behavior of inhomogeneous fibrin networks. Fibers in such networks buckle when in compression. We model this as a loss of stiffness in…

Biological Physics · Physics 2015-12-18 Phoebus Rosakis , Jacob Notbohm , Guruswami Ravichandran

We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

In this paper, the analysis and homogenization of a poroelastic model for the hydro-mechanical response of fibre-reinforced hydrogels is considered. Here, the medium in question is considered to be a highly heterogeneous two-component media…

Analysis of PDEs · Mathematics 2023-11-27 Michael Eden , Hari Shankar Mahato
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