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Bayesian sparse factor models have proven useful for characterizing dependence in multivariate data, but scaling computation to large numbers of samples and dimensions is problematic. We propose expandable factor analysis for scalable…

Methodology · Statistics 2018-06-21 Sanvesh Srivastava , Barbara E. Engelhardt , David B. Dunson

Biclustering is a powerful approach to search for patterns in data, as it can be driven by a function that measures the quality of diverse types of patterns of interest. However, due to its computational complexity, the exploration of the…

Machine Learning · Computer Science 2021-04-27 Marcin Michalak , Jesús S. Aguilar-Ruiz

Biclustering is a method for detecting homogeneous submatrices in a given observed matrix, and it is an effective tool for relational data analysis. Although there are many studies that estimate the underlying bicluster structure of a…

Methodology · Statistics 2021-07-16 Chihiro Watanabe , Taiji Suzuki

The Bayesian approach to feature extraction, known as factor analysis (FA), has been widely studied in machine learning to obtain a latent representation of the data. An adequate selection of the probabilities and priors of these bayesian…

Machine Learning · Statistics 2020-01-27 Carlos Sevilla-Salcedo , Vanessa Gómez-Verdejo , Pablo M. Olmos

Biclustering is a class of techniques that simultaneously clusters the rows and columns of a matrix to sort heterogeneous data into homogeneous blocks. Although many algorithms have been proposed to find biclusters, existing methods suffer…

Machine Learning · Statistics 2020-02-11 Michelle N. Ngo , Dustin S. Pluta , Alexander N. Ngo , Babak Shahbaba

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

Factor analysis has been extensively used to reveal the dependence structures among multivariate variables, offering valuable insight in various fields. However, it cannot incorporate the spatial heterogeneity that is typically present in…

Methodology · Statistics 2024-11-14 Yanxiu Jin , Tomoya Wakayama , Renhe Jiang , Shonosuke Sugasawa

Factor analysis is a critical component of high dimensional biological data analysis. However, modern biological data contain two key features that irrevocably corrupt existing methods. First, these data, which include longitudinal,…

Methodology · Statistics 2020-09-24 Chris McKennan

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

Quantitative Methods · Quantitative Biology 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

For most problems in science and engineering we can obtain data sets that describe the observed system from various perspectives and record the behavior of its individual components. Heterogeneous data sets can be collectively mined by data…

Machine Learning · Computer Science 2015-02-09 Marinka Žitnik , Blaž Zupan

We propose a generative model for robust tensor factorization in the presence of both missing data and outliers. The objective is to explicitly infer the underlying low-CP-rank tensor capturing the global information and a sparse tensor…

Computer Vision and Pattern Recognition · Computer Science 2016-06-21 Qibin Zhao , Guoxu Zhou , Liqing Zhang , Andrzej Cichocki , Shun-ichi Amari

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2018-09-19 Ioan Gabriel Bucur , Tom van Bussel , Tom Claassen , Tom Heskes

We propose and develop a Bayesian plaid model for biclustering that accounts for the prior dependency between genes (and/or conditions) through a stochastic relational graph. This work is motivated by the need for improved understanding of…

Applications · Statistics 2015-11-18 Thierry Chekouo , Alejandro Murua , Wolfgang Raffelsberger

Introduction The focus of analyzing data from microarray experiments and extracting biological insight from such data has experienced a shift from identification of individual genes in association with a phenotype to that of biological…

Genomics · Quantitative Biology 2015-08-10 Lei Zhang , Linlin Wang , Pu Tian , Suyan Tian

Analysis of multi-source dataset, where data on the same objects are collected from multiple sources, is of rising importance in many fields, most notably in multi-omics biology. A novel framework and algorithms for integrative…

Methodology · Statistics 2023-03-16 SeoWon Gabriel Choi , Sungkyu Jung

The search for sample-variable associations is an important problem in the exploratory analysis of high dimensional data. Biclustering methods search for sample-variable associations in the form of distinguished submatrices of the data…

Genomics · Quantitative Biology 2009-10-08 Andrey A. Shabalin , Victor J. Weigman , Charles M. Perou , Andrew B. Nobel

A novel unsupervised learning method is proposed in this paper for biclustering large-dimensional matrix-valued time series based on an entirely new latent two-way factor structure. Each block cluster is characterized by its own row and…

Methodology · Statistics 2025-02-11 Yong He , Xiaoyang Ma , Xingheng Wang , Yalin Wang

Deep multi-view clustering seeks to utilize the abundant information from multiple views to improve clustering performance. However, most of the existing clustering methods often neglect to fully mine multi-view structural information and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Jinrong Cui , Xiaohuang Wu , Haitao Zhang , Chongjie Dong , Jie Wen

Factor analysis is a flexible technique for assessment of multivariate dependence and codependence. Besides being an exploratory tool used to reduce the dimensionality of multivariate data, it allows estimation of common factors that often…

Applications · Statistics 2020-05-08 Vitor G. C. da Silva , Kelly C. M. Gonçalves , João B. M. Pereira

Biclustering is an effective technique in data mining and pattern recognition. Biclustering algorithms based on traditional clustering face two fundamental limitations when processing high-dimensional data: (1) The distance concentration…

Machine Learning · Computer Science 2025-05-01 Yan Huang , Da-Qing Zhang