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Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…

Neurons and Cognition · Quantitative Biology 2015-11-03 Alexander Lerchner , Peter E. Latham

Recently, some studies started to unveil the wealthy of interactions that occur between groups of nodes when looking at the small scale of interactions taking place in complex networks. Such findings claim for a new systematic methodology…

Physics and Society · Physics 2016-07-26 Cesar H. Comin , João B. Bunoro , Matheus P. Viana , Luciano da F. Costa

Understanding the mechanisms behind emergent behaviors in multi-agent systems is critical for advancing fields such as swarm robotics and artificial intelligence. In this study, we investigate how neural networks evolve to control agents'…

Adaptation and Self-Organizing Systems · Physics 2024-10-28 Guilherme S. Y. Giardini , John F. Hardy , Carlo R. da Cunha

In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional…

Neurons and Cognition · Quantitative Biology 2016-09-08 Mauro Copelli , Osame Kinouchi

Interacting individuals in complex systems often give rise to coherent motion exhibiting coordinated global structures. Such phenomena are ubiquitously observed in nature, from cell migration, bacterial swarms, animal and insect groups, and…

Neural and Evolutionary Computing · Computer Science 2024-07-17 Dongjo Kim , Jeongsu Lee , Ho-Young Kim

The dynamic range of stimulus processing in living organisms is much larger than a single neural network can explain. For a generic, tunable spiking network we derive that while the dynamic range is maximal at criticality, the interval of…

Disordered Systems and Neural Networks · Physics 2020-02-12 Johannes Zierenberg , Jens Wilting , Viola Priesemann , Anna Levina

Since the first experimental evidences of active conductances in dendrites, most neurons have been shown to exhibit dendritic excitability through the expression of a variety of voltage-gated ion channels. However, despite experimental and…

Neurons and Cognition · Quantitative Biology 2012-01-18 Leonardo L. Gollo , Osame Kinouchi , Mauro Copelli

The connectome, or the entire connectivity of a neural system represented by network, ranges various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they…

Neurons and Cognition · Quantitative Biology 2014-10-01 Jinseop S. Kim , Marcus Kaiser

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

The brain's diversity of neurons enables a rich behavioral repertoire and flexible adaptation to new situations. Assuming that the ecological pressure has optimized this neuronal variety, we propose exploiting na\"ive behavior to map the…

Neurons and Cognition · Quantitative Biology 2023-05-01 Kevin Luxem , David Eriksson

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

For studying how dynamical responses to external stimuli depend on the synaptic-coupling type, we consider two types of excitatory and inhibitory synchronization (i.e., synchronization via synaptic excitation and inhibition) in complex…

Neurons and Cognition · Quantitative Biology 2016-11-29 Sang-Yoon Kim , Woochang Lim

Inhibition is considered to shape neural activity, and broaden its pattern repertoire. In the sensory organs, where the anatomy of neural circuits is highly structured, lateral inhibition sharpens contrast among stimulus properties. The…

Neurons and Cognition · Quantitative Biology 2018-09-18 Netta Haroush , Shimon Marom

The presence of correlated noise, arising from a mixture of independent fluctuations and a common noisy input shared across the neural population, is a ubiquitous feature of neural circuits, yet its impact on collective network dynamics…

Neurons and Cognition · Quantitative Biology 2026-01-16 Hui Wang , Chunming Zheng

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

Neurons and Cognition · Quantitative Biology 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Many dynamical systems found in biology, ranging from genetic circuits to the human brain to human social systems, are inherently computational. Although extensive research has explored their resulting functions and behaviors, the…

Neurons and Cognition · Quantitative Biology 2025-04-15 Junang Li , Andrew M. Leifer , David H. Wolpert

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

Neurons and Cognition · Quantitative Biology 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

All higher order central nervous systems exhibit spontaneous neural activity, though the purpose and mechanistic origin of such activity remains poorly understood. We explore the ignition and spread of collective spontaneous…

Neurons and Cognition · Quantitative Biology 2010-04-14 Michael I. Ham , Vadas Gintautas , Guenter W. Gross

To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with…

Neurons and Cognition · Quantitative Biology 2008-06-10 Jan Karbowski , Gary Schindelman , Chris J. Cronin , Adeline Seah , Paul W. Sternberg
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