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Decoding the heterogeneity of biological neural systems is key to understanding the nervous system's complex dynamical behaviors. This study analyzes the comprehensive Drosophila brain connectome, which is the most recent data set,…

Neurons and Cognition · Quantitative Biology 2025-10-01 Xiaoyu Zhang , Pengcheng Yang , Yifei Zhang , Bowei Qin , Qiang Luo , Wei Lin , Xin Lu

Objective: In recent years, the functional connectivity of the human brain has been studied with graph theoretical tools. One such approach is community detection which is fundamental for uncovering the localized networks. Existing methods…

Signal Processing · Electrical Eng. & Systems 2022-09-27 Abdullah Karaaslanli , Meiby Ortiz-Bouza , Tamanna T. K. Munia , Selin Aviyente

We present an approach to study functional segregation and integration in the living brain based on community structure decomposition determined by maximum modularity. We demonstrate this method with a network derived from functional…

Neurons and Cognition · Quantitative Biology 2007-05-23 Adam J. Schwarz , Alessandro Gozzi , Angelo Bifone

Many real-world networks, including nervous systems, exhibit meso-scale structure. This means that their elements can be grouped into meaningful sub-networks. In general, these sub-networks are unknown ahead of time and must be "discovered"…

Neurons and Cognition · Quantitative Biology 2020-11-16 Richard F. Betzel

Functional magnetic resonance imaging (fMRI) has been commonly used to construct functional connectivity networks (FCNs) of the human brain. TFCNs are primarily limited to quantifying pairwise relationships between ROIs ignoring higher…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Duc Vu , Selin Aviyente

The complete connectome of the Drosophila larva brain offers a unique opportunity to investigate whether biologically evolved circuits can support artificial intelligence. We convert this wiring diagram into a Biological Processing Unit…

Neural and Evolutionary Computing · Computer Science 2025-07-16 Siyu Yu , Zihan Qin , Tingshan Liu , Beiya Xu , R. Jacob Vogelstein , Jason Brown , Joshua T. Vogelstein

The first step to understanding brain function is to determine the brain's network structure. We report a three-dimensional analysis of the brain network of the fruit fly Drosophila melanogaster by synchrotron-radiation tomographic…

Neurons and Cognition · Quantitative Biology 2016-09-09 Ryuta Mizutani , Rino Saiga , Akihisa Takeuchi , Kentaro Uesugi , Yoshio Suzuki

The collective behavior of a network with heterogeneous, resource-limited information processing units (e.g., group of fish, flock of birds, or network of neurons) demonstrates high self-organization and complexity. These emergent…

Machine Learning · Computer Science 2023-10-13 Chenzhong Yin , Mingxi Cheng , Xiongye Xiao , Xinghe Chen , Shahin Nazarian , Andrei Irimia , Paul Bogdan

Community detection is a ubiquitous problem in applied network analysis, yet efficient techniques do not yet exist for all types of network data. Most techniques have been developed for undirected graphs, and very few exist that handle…

Physics and Society · Physics 2023-04-26 Botond Molnár , Ildikó-Beáta Márton , Szabolcs Horvát , Mária Ercsey-Ravasz

Accurately predicting individual neurons' responses and spatial functional properties in complex visual tasks remains a key challenge in understanding neural computation. Existing whole-brain connectome models of Drosophila often rely on…

Neurons and Cognition · Quantitative Biology 2025-12-09 Jiangping Xie , Ruohan Ren , Xiao Zhou , Ao Zheng , Jiasong Zhu , Wenyu Jiang , Ziran Zhao

In this paper, we present a new method for detecting overlapping communities in networks with a predefined number of clusters called LPAM (Link Partitioning Around Medoids). The overlapping communities in the graph are obtained by detecting…

Social and Information Networks · Computer Science 2021-04-27 Alexander Ponomarenko , Leonidas Pitsoulis , Marat Shamshetdinov

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

We present results related to the performance of an algorithm for community detection which incorporates event-driven computation. We define a mapping which takes a graph G to a system of spiking neurons. Using a fully connected spiking…

Neural and Evolutionary Computing · Computer Science 2017-11-21 Kathleen E. Hamilton , Neena Imam , Travis S. Humble

Multiplex networks have emerged as a promising approach for modeling complex systems, where each layer represents a different mode of interaction among entities of the same type. A core task in analyzing these networks is to identify the…

Social and Information Networks · Computer Science 2024-11-11 Meiby Ortiz-Bouza , Selin Aviyente

Most functional magnetic resonance imaging studies rely on estimates of hierarchically organized functional brain networks whose segregation and integration reflect the cognitive and behavioral changes in humans. However, most existing…

Neurons and Cognition · Quantitative Biology 2026-04-17 Lingbin Bian , Nizhuan Wang , Leonardo Novelli , Jonathan Keith , Adeel Razi

With the recent explosion of publicly available biological data, the analysis of networks has gained significant interest. In particular, recent promising results in Neuroscience show that the way neurons and areas of the brain are…

Social and Information Networks · Computer Science 2015-11-17 Umberto Esposito , Eleni Vasilaki

Naturally occurring networks exhibit quantitative features revealing underlying growth mechanisms. Numerous network mechanisms have recently been proposed to reproduce specific properties such as degree distributions or clustering…

Quantitative Methods · Quantitative Biology 2009-11-10 Manuel Middendorf , Etay Ziv , Chris Wiggins

Community detection algorithms have been widely used to study the organization of complex systems like the brain. A principal appeal of these techniques is their ability to identify a partition of brain regions (or nodes) into communities,…

Neurons and Cognition · Quantitative Biology 2017-04-20 Arian Ashourvan , Qawi K. Telesford , Timothy Verstynen , Jean M. Vettel , Danielle S. Bassett

Community detection is an important information mining task to uncover modular structures in large networks. For increasingly common large network data sets, global community detection is prohibitively expensive, and attention has shifted…

Social and Information Networks · Computer Science 2019-05-17 Kun He , Pan Shi , David Bindel , John E. Hopcroft

Many networks exhibit some community structure. There exists a wide variety of approaches to detect communities in networks, each offering different interpretations and associated algorithms. For large networks, there is the additional…

Physics and Society · Physics 2023-02-16 Vincent A. Traag , Lovro Šubelj
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