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Related papers: A Relaxed Drift Diffusion Model for Phylogenetic T…

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A trained ML model is deployed on another `test' dataset where target feature values (labels) are unknown. Drift is distribution change between the training and deployment data, which is concerning if model performance changes. For a…

Applications · Statistics 2022-09-07 Samuel Ackerman , Eitan Farchi , Orna Raz , Marcel Zalmanovici , Parijat Dube

Human decision making behavior is observed with choice-response time data during psychological experiments. Drift-diffusion models of this data consist of a Wiener first-passage time (WFPT) distribution and are described by cognitive…

Neurons and Cognition · Quantitative Biology 2022-08-18 Qinhua Jenny Sun , Khuong Vo , Kitty Lui , Michael Nunez , Joachim Vandekerckhove , Ramesh Srinivasan

Motivated by observations in sequence data of herpesviruses, we introduce a multi-locus model for the joint evolution of different genotypes in a virus population that is distributed across a population of hosts. In the model, virus…

Populations and Evolution · Quantitative Biology 2025-09-24 Raphael Eichhorn , Cornelia Pokalyuk

We address diffusion processes in a bounded domain, while focusing on somewhat unexplored affinities between the presence of absorbing and/or inaccessible boundaries. For the Brownian motion (L\'{e}vy-stable cases are briefly mentioned)…

Statistical Mechanics · Physics 2017-10-24 Piotr Garbaczewski

Motivated by a down-up Markov chain on cladograms, David Aldous conjectured in 1999 that there exists a "diffusion on continuum trees" whose mass partitions at any finite number of branch points evolve as Wright-Fisher diffusions with some…

Probability · Mathematics 2023-05-30 Noah Forman , Soumik Pal , Douglas Rizzolo , Matthias Winkel

We derive the first-passage-time statistics of a Brownian motion driven by an exponential time-dependent drift up to a threshold. This process corresponds to the signal integration in a simple neuronal model supplemented with an…

Statistical Mechanics · Physics 2012-04-30 Eugenio Urdapilleta

We study the problem of drift estimation for two-scale continuous time series. We set ourselves in the framework of overdamped Langevin equations, for which a single-scale surrogate homogenized equation exists. In this setting, estimating…

Numerical Analysis · Mathematics 2021-06-08 Assyr Abdulle , Giacomo Garegnani , Grigorios A. Pavliotis , Andrew M. Stuart , Andrea Zanoni

We apply macroscopic fluctuation theory to study the diffusion of a tracer in a one-dimensional interacting particle system with excluded mutual passage, known as single-file diffusion. In the case of Brownian point particles with hard-core…

Statistical Mechanics · Physics 2014-11-18 P. L. Krapivsky , Kirone Mallick , Tridib Sadhu

The parallel mutation-selection evolutionary dynamics, in which mutation and replication are independent events, is solved exactly in the case that the Malthusian fitnesses associated to the genomes are described by the Random Energy Model…

Biological Physics · Physics 2009-10-14 David B. Saakian , José F. Fontanari

Estimating population-level prevalence and transmission dynamics of wildlife pathogens can be challenging, partly because surveillance data is sparse, detection-driven, and unevenly sequenced. Using highly pathogenic avian influenza A/H5…

Populations and Evolution · Quantitative Biology 2026-01-16 Haley Stone , Jing Du , Yang Yang , Ashna Desai , Rebecca Dawson , Hao Xue , David Heslop , Matthew Scotch , Andreas Züfle , C. Raina MacIntyre , Flora Salim

We study the asymptotic behavior of an integro-dierential equation describing the evolutionary adaptation of a population structured by a phenotypic trait. The model takes into account mutation, selection, horizontal gene transfer and…

Analysis of PDEs · Mathematics 2026-04-03 Alejandro Gárriz , Sepideh Mirrahimi

This study focuses on the modeling, mathematical analysis, developing theories, and numerical simulation of Influenza virus transmission. We have proved the existence, uniqueness, positivity, and boundedness of the solutions. Also,…

Populations and Evolution · Quantitative Biology 2024-03-19 Kazi Mehedi Mohammad , Asma Akter Akhi , Md. Kamrujjaman

Consider the sample path of a one-dimensional diffusion for which the diffusion coefficient is given and where the drift may take on one of two values: $\mu_0$ or $\mu_1$. Suppose that the signal-to-noise ratio (defined as the difference…

Optimization and Control · Mathematics 2023-11-02 Philip Ernst , Hongwei Mei

Reaction-diffusion equations are widely used as the governing evolution equations for modeling many physical, chemical, and biological processes. Here we derive reaction-diffusion equations to model transport with reactions on a…

Statistical Mechanics · Physics 2020-09-16 E. Abad , C. N. Angstmann , B. I. Henry , A. V. McGann , F. Le Vot , S. B. Yuste

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

In this paper we revisit and adapt to viral evolution an approach based on the theory of branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution and branching processes", Bull. Math. Biol. 46 (1985)…

Populations and Evolution · Quantitative Biology 2014-02-11 Fernando Antoneli , Francisco Bosco , Diogo Castro , Luiz Mario Janini

We quantify the asymptotic behaviour of multidimensional drifltess diffusions in domains unbounded in a single direction, with asymptotically normal reflections from the boundary. We identify the critical growth/contraction rates of the…

Probability · Mathematics 2025-01-22 Miha Brešar , Aleksandar Mijatović , Andrew Wade

To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

Intraspecific trait variation has been increasingly recognized as an important factor in determining species interaction and diversity. Eco-evolutionary models have studied the distribution of trait values within a population that changes…

Populations and Evolution · Quantitative Biology 2023-10-12 Zachary Jackson , BingKan Xue

Standard diffusion equation is based on Brownian motion of the dispersing species without considering persistence in the movement of the individuals. This description allows for the instantaneous spreading of the transported species over an…

Pattern Formation and Solitons · Physics 2020-07-13 Pushpita Ghosh , Deb Shankar Ray
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