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Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a…

Machine Learning · Computer Science 2020-10-14 Michael B. Mayhew , Elizabeth Tran , Kirindi Choi , Uros Midic , Roland Luethy , Nandita Damaraju , Ljubomir Buturovic

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

We study individual-based dynamics in finite populations, subject to randomly switching environmental conditions. These are inspired by models in which genes transition between on and off states, regulating underlying protein dynamics.…

Statistical Mechanics · Physics 2016-05-18 Peter G. Hufton , Yen Ting Lin , Tobias Galla , Alan J. McKane

We study a dynamics of the epidemiological infection spreading at different values of the risk factor $\beta$ (a control parameter) with the using of dynamic Monte Carlo approach (DMC). In our toy model, the infection transmits due to…

Physics and Society · Physics 2020-06-01 Gennadiy Burlak

Malware attacks in today's vast digital ecosystem pose a serious threat. Understanding malware propagation dynamics and designing effective control strategies are therefore essential. In this work, we propose a generic SEIRV model…

Cryptography and Security · Computer Science 2026-03-05 Samiran Ghosh , V Anil Kumar

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

Stochastic compartmental models are important tools for understanding the course of infectious diseases epidemics in populations and in prospective evaluation of intervention policies. However, calculating the likelihood for discretely…

Computation · Statistics 2018-07-26 Lam Si Tung Ho , Forrest W. Crawford , Marc A. Suchard

In many biological systems, chemical reactions or changes in a physical state are assumed to occur instantaneously. For describing the dynamics of those systems, Markov models that require exponentially distributed inter-event times have…

Populations and Evolution · Quantitative Biology 2020-07-06 Wasiur R. KhudaBukhsh , Hye-Won Kang , Eben Kenah , Grzegorz A. Rempala

We consider exchangeable Markov multi-state survival processes -- temporal processes taking values over a state-space$\mathcal{S}$ with at least one absorbing failure state $\flat \in \mathcal{S}$ that satisfy natural invariance properties…

Methodology · Statistics 2018-10-26 Walter Dempsey

Background: Mathematical models based on ordinary differential equations (ODEs) are essential tools across various scientific disciplines, including biology, ecology, and healthcare informatics. They are used to simulate complex dynamic…

Quantitative Methods · Quantitative Biology 2025-09-03 Hamed Karami , Amanda Bleichrodt , Ruiyan Luo , Gerardo Chowell

Exposure assessment models are deterministic models derived from physical-chemical laws. In real workplace settings, chemical concentration measurements can be noisy and indirectly measured. In addition, inference on important parameters…

Applications · Statistics 2018-07-09 Nada Abdalla , Sudipto Banerjee , Gurumurthy Ramachandran , Susan Arnold

This paper develops a Bayesian mechanics for adaptive systems. Firstly, we model the interface between a system and its environment with a Markov blanket. This affords conditions under which states internal to the blanket encode information…

Mathematical Physics · Physics 2021-12-22 Lancelot Da Costa , Karl Friston , Conor Heins , Grigorios A. Pavliotis

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Multi-state survival analysis considers several potential events of interest along a disease pathway. Such analyses are crucial to model complex patient trajectories and are increasingly being used in epidemiological and health economic…

Methodology · Statistics 2021-04-30 Jonathan Broomfield , Caroline E. Weibull , Michael J. Crowther

Civil and maritime engineering systems, among others, from bridges to offshore platforms and wind turbines, must be efficiently managed as they are exposed to deterioration mechanisms throughout their operational life, such as fatigue or…

Artificial Intelligence · Computer Science 2021-11-30 P. G. Morato , K. G. Papakonstantinou , C. P. Andriotis , J. S. Nielsen , P. Rigo

Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…

Populations and Evolution · Quantitative Biology 2026-01-27 Alex Viguerie , Malú Grave , Alvaro L. G. A. Coutinho , Alessandro Veneziani , Thomas J. R. Hughes

Stochastic epidemic models, generally more realistic than deterministic counterparts, have often been seen too complex for rigorous mathematical analysis because of level of details it requires to comprehensively capture the dynamics of…

Populations and Evolution · Quantitative Biology 2018-06-13 Xin Liu , Anuj Mubayi , Dominik Reinhold , Liu Zhu

Ordinary differential equations (ODEs) are a mathematical model used in many application areas such as climatology, bioinformatics, and chemical engineering with its intuitive appeal to modeling. Despite ODE's wide usage in modeling, the…

Applications · Statistics 2021-08-10 Hyunjoo Yang , Jaeyong Lee

We introduce an interacting particle system that models the spread of an epidemic in terms of heterogeneous diffusive dynamics, rather than exogenous contact and transmission rates at the population level as in classical compartmental…

Probability · Mathematics 2026-05-20 Eliana Fausti , Andreas Sojmark

We study the stochastic susceptible-infected-recovered (SIR) model with time-dependent forcing using analytic techniques which allow us to disentangle the interaction of stochasticity and external forcing. The model is formulated as a…

Populations and Evolution · Quantitative Biology 2010-11-23 Andrew J Black , Alan J McKane
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