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Improving the resolution of fluorescence microscopy beyond the diffraction limit can be achievedby acquiring and processing multiple images of the sample under different illumination conditions.One of the simplest techniques, Random…

This work is concerned with optical imaging in strongly diffusive environments. We consider a typical setting in optical coherence tomography where a sample is probed by a collection of wavefields produced by a laser and propagating through…

Optics · Physics 2024-12-10 Randy Bartels , Olivier Pinaud , Maxine Varughese

Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Encoding of spectral information onto monochrome imaging cameras is of interest for wavelength multiplexing and hyperspectral imaging applications. Here, the complex spatio-spectral response of a disordered material is used to demonstrate…

Optics · Physics 2017-05-09 Rebecca French , Sylvain Gigan , Otto L. Muskens

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Speckle-correlation imaging techniques are widely used for non-invasive imaging through complex scattering media. While light propagation through multimode fibers and scattering media share many analogies, reconstructing images through…

Light passing through scattering media will be strongly scattered and diffused into complex speckle pattern, which contains almost all the spatial information and spectral information of the objects. Although various methods have been…

Optics · Physics 2019-02-04 Lei Zhu , Jietao Liu , Lei Feng , Chengfei Guo , Tengfei Wu , Xiaopeng Shao

Scattering obscures information carried by wave by producing a speckle pattern, posing a common challenge across various fields, including microscopy and astronomy. Traditional methods for extracting information from speckles often rely on…

Many imaging applications require increasingly bright illumination sources, motivating the replacement of conventional thermal light sources with light emitting diodes (LEDs), superluminescent diodes (SLDs) and lasers. Despite their…

Optics · Physics 2017-04-05 Brandon Redding , Michael A. Choma , Hui Cao

Speckle noise is an inherent disturbance in coherent imaging systems such as digital holography, synthetic aperture radar, optical coherence tomography, or ultrasound systems. These systems usually produce only single observation per view…

Image and Video Processing · Electrical Eng. & Systems 2022-05-19 Tsung-Ming Tai , Yun-Jie Jhang , Wen-Jyi Hwang , Chau-Jern Cheng

Laser speckle, the granular intensity pattern arising from random optical interference, provides a high-dimensional encoding of spectral information that can be exploited for precision metrology. Speckle-based spectrometers have advanced…

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Optical stellar interferometers have demonstrated milli-arcsecond resolution with few apertures spaced hundreds of meters apart. To obtain rich direct images, many apertures will be needed, for a better sampling of the incoming wavefront.…

Instrumentation and Methods for Astrophysics · Physics 2014-09-17 Arun Surya , Swapan K. Saha , Antoine Labeyrie

Due to the complex of mixed spectral point spread function within memory effect range, it is unreliable and slow to use speckle correlation technology for non-invasive imaging through scattering medium under broadband illumination. The…

Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…

Optics · Physics 2024-05-01 Tengfei Wu , YoonSeok Baek , Fei Xia , Sylvain Gigan , Hilton B. de Aguiar

The resolution limits of classical spectroscopy can be surpassed by quantum-inspired methods leveraging the information contained in the phase of the complex electromagnetic field. Their counterpart in spatial imaging has been widely…

Optics · Physics 2024-09-02 Michał Lipka , Michał Parniak

Imaging through scattering media is a longstanding issue in a wide range of applications, including biomedicine, security, and astronomy. Speckle-correlation imaging is promising for non-invasively seeing through scattering media by…

Optics · Physics 2022-10-13 Yuto Endo , Jun Tanida , Makoto Naruse , Ryoichi Horisaki

Speckles arise when coherent light interacts with biological tissues. Information retrieval from speckles is desired yet challenging, requiring understanding or mapping of the multiple scattering process, or reliable capability to reverse…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Huanhao Li , Zhipeng Yu , Yunqi Luo , Shengfu Cheng , Lihong V. Wang , Yuanjin Zheng , Puxiang Lai

In some super-resolution techniques, adjacent points are illuminated at different times. Thereby, their locations and light intensities can be detected even if the images are very blurred due to diffraction. According to conventional…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Edward Y. Sheffield

Recently, novel imaging techniques based on the 'memory-effect' speckle-correlations have enabled diffraction-limited imaging through scattering layers and around corners. These techniques, however, are currently limited to imaging only…

Optics · Physics 2018-11-14 Ofer Salhov , Gil Weinberg , Ori Katz
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