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Artificial intelligence research to a great degree focuses on the brain and behaviors that the brain generates. But the brain, an extremely complex structure resulting from millions of years of evolution, can be viewed as a solution to…

Neurons and Cognition · Quantitative Biology 2017-03-07 Thomas E. Portegys

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

This paper presents a highly speculative model encompassing the cortex, thalamus, and hippocampus of the mammalian brain. While the majority of computational neuroscience models are founded upon empirical evidence, this model is predicated…

Neurons and Cognition · Quantitative Biology 2024-05-22 Valentin Puente-Varona

The human brain is a complex inter-wired system that emerges spontaneous functional fluctuations. In spite of tremendous success in the experimental neuroscience field, a system-level understanding of how brain anatomy supports various…

Neurons and Cognition · Quantitative Biology 2024-05-28 Tingting Dan , Ziquan Wei , Won Hwa Kim , Guorong Wu

State of the art deep reinforcement learning algorithms take many millions of interactions to attain human-level performance. Humans, on the other hand, can very quickly exploit highly rewarding nuances of an environment upon first…

Memory for the past makes use of a record of what happened when---a function over past time. Time cells in the hippocampus and temporal context cells in the entorhinal cortex both code for events as a function of past time, but with very…

Neurons and Cognition · Quantitative Biology 2020-03-27 Marc W. Howard , Michael E. Hasselmo

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

Representing dynamical systems through data-driven universal spaces has proven effective; however, achieving this universality for human brain activity remains a significant challenge, further aggravated by diverse cognitive states and…

Quantitative Methods · Quantitative Biology 2026-05-06 Ronghua Zheng , Chengyuan Qian , Weiyang Ding

Present day computers expend orders of magnitude more computational resources to perform various cognitive and perception related tasks that humans routinely perform everyday. This has recently resulted in a seismic shift in the field of…

Emerging Technologies · Computer Science 2017-12-22 Abhronil Sengupta , Kaushik Roy

A hallmark of human intelligence is the ability to adapt to new situations, by applying learned rules to new content (systematicity) and thereby enabling an open-ended number of inferences and actions (generativity). Here, we propose that…

Neurons and Cognition · Quantitative Biology 2021-08-10 Randall C. O'Reilly , Charan Ranganath , Jacob L. Russin

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Recent whole brain imaging experiments on $\textit{C. elegans}$ has revealed that the neural population dynamics encode motor commands and stereotyped transitions between behaviors on low dimensional manifolds. Efforts to characterize the…

Quantitative Methods · Quantitative Biology 2020-04-15 Charles Fieseler , Manuel Zimmer , J. Nathan Kutz

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

Artificial Intelligence (AI) systems based solely on neural networks or symbolic computation present a representational complexity challenge. While minimal representations can produce behavioral outputs like locomotion or simple…

Neurons and Cognition · Quantitative Biology 2022-10-19 Bradly Alicea , Jesse Parent

The human brain is the most powerful and efficient machine in existence today, surpassing in many ways the capabilities of modern computers. Currently, lines of research in neuromorphic engineering are trying to develop hardware that mimics…

Neural and Evolutionary Computing · Computer Science 2022-10-06 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno

This article explores the design and experimentation of a neural network architecture capable of dynamically adjusting its internal structure based on the input data. The proposed model introduces a routing mechanism that allows each layer…

Machine Learning · Computer Science 2025-11-18 Dmytro Hospodarchuk

A major challenge in neuroscience is posed by the need for relating the emerging dynamical features of brain activity with the underlying modular structure of neural connections, hierarchically organized throughout several scales. The…

Neurons and Cognition · Quantitative Biology 2016-06-03 Pablo Villegas , Jorge Hidalgo , Paolo Moretti , Miguel A. Muñoz

Information processing in the brain is coordinated by the dynamic activity of neurons and neural populations at a range of spatiotemporal scales. These dynamics, captured in the form of electrophysiological recordings and neuroimaging, show…

Neurons and Cognition · Quantitative Biology 2025-10-27 Ramón Nartallo-Kaluarachchi , Morten L. Kringelbach , Gustavo Deco , Renaud Lambiotte , Alain Goriely

The brain has computational capabilities that surpass those of modern systems, being able to solve complex problems efficiently in a simple way. Neuromorphic engineering aims to mimic biology in order to develop new systems capable of…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno

Technological advances have dramatically expanded our ability to probe multi-neuronal dynamics and connectivity in the brain. However, our ability to extract a simple conceptual understanding from complex data is increasingly hampered by…

Neurons and Cognition · Quantitative Biology 2015-03-31 Peiran Gao , Surya Ganguli