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Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Human-Computer Interaction · Computer Science 2025-10-03 Mattea Reid , Zuhairah Zainal , Khaing Zin Than , Danielle Chan , Jonathan Chan

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Imane Nedjar , Mohammed Brahimi , Said Mahmoudi , Khadidja Abi Ayad , Mohammed Amine Chikh

Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing…

Image and Video Processing · Electrical Eng. & Systems 2021-01-22 David Joon Ho , Dig V. K. Yarlagadda , Timothy M. D'Alfonso , Matthew G. Hanna , Anne Grabenstetter , Peter Ntiamoah , Edi Brogi , Lee K. Tan , Thomas J. Fuchs

Accurate characterization of carbon nanotube morphologies in electron microscopy images is vital for exposure assessment and toxicological studies, yet current workflows rely on slow, subjective manual segmentation. This work presents a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Sanjay Pradeep , Chen Wang , Matthew M. Dahm , Jeff D. Eldredge , Candace S. J. Tsai

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr

Recent work suggests that quantum machine learning techniques can be used for classical image classification by encoding the images in quantum states and using a quantum neural network for inference. However, such work has been restricted…

Quantum Physics · Physics 2021-10-13 Ali Mohsen , Mo Tiwari

Segmentations are often necessary for the analysis of image data. They are used to identify different objects, for example cell nuclei, mitochondria, or complete cells in microscopic images. There might be features in the data, that cannot…

Computational Geometry · Computer Science 2016-05-31 Julia Portl , Heike Leitte

Quality control (QC) of medical images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually at significant time and operator cost. We aim to…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy

As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Adrian Galdran , Miguel A. González Ballester

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

Intracellular structural alterations are hallmark of several disease conditions and treatment modalities. However, robust methods to quantify these changes are scarce. In view of this, we introduce a new method to quantify structural…

Accurate segmentation of thalamic nuclei is important for better understanding brain function and improving disease treatment. Traditional segmentation methods often rely on a single T1-weighted image, which has limited contrast in the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Anqi Feng , Zhangxing Bian , Blake E. Dewey , Alexa Gail Colinco , Jiachen Zhuo , Jerry L. Prince

Segmenting medical images is critical to facilitating both patient diagnoses and quantitative research. A major limiting factor is the lack of labeled data, as obtaining expert annotations for each new set of imaging data and task can be…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Chen Liu , Matthew Amodio , Liangbo L. Shen , Feng Gao , Arman Avesta , Sanjay Aneja , Jay C. Wang , Lucian V. Del Priore , Smita Krishnaswamy

Image Quality Assessment (IQA) is important for scientific inquiry, especially in medical imaging and machine learning. Potential data quality issues can be exacerbated when human-based workflows use limited views of the data that may…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Riqiang Gao , Mirza S. Khan , Yucheng Tang , Kaiwen Xu , Steve Deppen , Yuankai Huo , Kim L. Sandler , Pierre P. Massion , Bennett A. Landman

Quantum Computing and especially Quantum Machine Learning, in a short period of time, has gained a lot of interest through research groups around the world. This can be seen in the increasing number of proposed models for pattern…

Quantum Physics · Physics 2020-12-23 Héctor Iván García Hernández , Raymundo Torres Ruiz , Guo-Hua Sun

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Accurate cell segmentation in pathology images typically requires dense pixel-wise annotations, which are costly and time-consuming to obtain. This challenge is especially important for emerging biological imaging modalities and multiplexed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gunjan Shrivastava , Saad Nadeem