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A central statistical problem in population genetics is to infer evolutionary and biological parameters such as the strength of natural selection and allele age from DNA samples extracted from a contemporary population. That all samples…

Populations and Evolution · Quantitative Biology 2025-02-19 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spano

Approximate Bayesian Computation (ABC) is a popular inference method when likelihoods are hard to come by. Practical bottlenecks of ABC applications include selecting statistics that summarize the data without losing too much information or…

Computation · Statistics 2026-05-15 Khanh N. Dinh , Cécile Liu , Zijin Xiang , Zhihan Liu , Simon Tavaré

Inference of the evolutionary histories of species, commonly represented by a species tree, is complicated by the divergent evolutionary history of different parts of the genome. Different loci on the genome can have different histories…

Populations and Evolution · Quantitative Biology 2020-10-14 Andrew Richards , Laura Kubatko

In phylogenomics, species-tree methods must contend with two major sources of noise; stochastic gene-tree variation under the multispecies coalescent model (MSC) and finite-sequence substitutional noise. Fast agglomerative methods such as…

Populations and Evolution · Quantitative Biology 2025-07-11 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

Bayesian inference has predominantly relied on the Markov chain Monte Carlo (MCMC) algorithm for many years. However, MCMC is computationally laborious, especially for complex phylogenetic models of time trees. This bottleneck has led to…

Populations and Evolution · Quantitative Biology 2024-06-27 Mathieu Fourment , Matthew Macaulay , Christiaan J Swanepoel , Xiang Ji , Marc A Suchard , Frederick A Matsen

A new Bayesian modelling framework is introduced for piece-wise homogeneous variable-memory Markov chains, along with a collection of effective algorithmic tools for change-point detection and segmentation of discrete time series. Building…

Methodology · Statistics 2025-01-14 Valentinian Lungu , Ioannis Papageorgiou , Ioannis Kontoyiannis

Species networks generalize the notion of species trees to allow for hybridization or other lateral gene transfer. Under the Network Multispecies Coalescent Model, individual gene trees arising from a network can have any topology, but…

Populations and Evolution · Quantitative Biology 2019-05-20 Elizabeth Allman , Hector Banos , John Rhodes

Multiple Classifier Systems (MCSs) allow evaluation of the uncertainty of classification outcomes that is of crucial importance for safety critical applications. The uncertainty of classification is determined by a trade-off between the…

We consider Bayesian inference in sequential latent variable models in general, and in nonlinear state space models in particular (i.e., state smoothing). We work with sequential Monte Carlo (SMC) algorithms, which provide a powerful…

Computation · Statistics 2015-05-26 Fredrik Lindsten , Pete Bunch , Sumeetpal S. Singh , Thomas B. Schön

In many problems, complex non-Gaussian and/or nonlinear models are required to accurately describe a physical system of interest. In such cases, Monte Carlo algorithms are remarkably flexible and extremely powerful approaches to solve such…

Computation · Statistics 2015-04-23 Thi Le Thu Nguyen , Francois Septier , Gareth W. Peters , Yves Delignon

We show that genealogical trees arising from a broad class of non-neutral models of population evolution converge to the Kingman coalescent under a suitable rescaling of time. As well as non-neutral biological evolution, our results apply…

Probability · Mathematics 2025-04-09 Jere Koskela , Paul A. Jenkins , Adam M. Johansen , Dario Spano

In many applications of Bayesian clustering, posterior sampling on the discrete state space of cluster allocations is achieved via Markov chain Monte Carlo (MCMC) techniques. As it is typically challenging to design transition kernels to…

Computation · Statistics 2019-06-14 Masoud Asgharian , Martin Lysy , Vahid Partovi Nia

Selection among alternative theoretical models given an observed data set is an important challenge in many areas of physics and astronomy. Reversible-jump Markov chain Monte Carlo (RJMCMC) is an extremely powerful technique for performing…

Instrumentation and Methods for Astrophysics · Physics 2015-06-25 Will M. Farr , Ilya Mandel , Daniel Stevens

Markov chain Monte Carlo (MCMC) algorithms are generally regarded as the gold standard technique for Bayesian inference. They are theoretically well-understood and conceptually simple to apply in practice. The drawback of MCMC is that in…

Computation · Statistics 2019-07-17 Christopher Nemeth , Paul Fearnhead

Model-based reinforcement learning (RL) methods that leverage search are responsible for many milestone breakthroughs in RL. Sequential Monte Carlo (SMC) recently emerged as an alternative to the Monte Carlo Tree Search (MCTS) algorithm…

Machine Learning · Computer Science 2026-05-22 Yaniv Oren , Joery A. de Vries , Pascal R. van der Vaart , Matthijs T. J. Spaan , Wendelin Böhmer

Decision trees are highly famous in machine learning and usually acquire state-of-the-art performance. Despite that, well-known variants like CART, ID3, random forest, and boosted trees miss a probabilistic version that encodes prior…

Artificial Intelligence · Computer Science 2022-07-27 Efthyvoulos Drousiotis , Paul G. Spirakis

We introduce a family of multiscale stick-breaking mixture models for Bayesian nonparametric density estimation. The Bayesian nonparametric literature is dominated by single scale methods, exception made for P\`olya trees and allied…

Methodology · Statistics 2020-01-17 Marco Stefanucci , Antonio Canale

A number of methods have been developed to infer differential rates of species diversification through time and among clades using time-calibrated phylogenetic trees. However, we lack a general framework that can delineate and quantify…

Quantitative Methods · Quantitative Biology 2015-06-18 Daniel L. Rabosky

The Markov Chain Monte Carlo (MCMC) algorithm is a widely recognised as an efficient method for sampling a specified posterior distribution. However, when the posterior is multi-modal, conventional MCMC algorithms either tend to become…

Instrumentation and Methods for Astrophysics · Physics 2014-08-19 Yi-Ming Hu , Martin Hendry , Ik Siong Heng

We develop a new Bayesian modelling framework for the class of higher-order, variable-memory Markov chains, and introduce an associated collection of methodological tools for exact inference with discrete time series. We show that a version…