Related papers: A Conversation with Nan Laird

Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…

We train and validate a semi-supervised, multi-task LSTM on 57,675 person-weeks of data from off-the-shelf wearable heart rate sensors, showing high accuracy at detecting multiple medical conditions, including diabetes (0.8451), high…

Privacy-preserving machine learning is one class of cryptographic methods that aim to analyze private and sensitive data while keeping privacy, such as homomorphic logistic regression training over large encrypted data. In this paper, we…

Electrocardiograms (ECGs) provide non-invasive measurements of heart activity and are established tools for detecting cardiac arrhythmias. Although supervised machine learning has emerged as a promising approach for automated heartbeat…

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Gestational Diabetes Mellitus (GDM) is a high-prevalence pregnancy complication that requires accurate early risk stratification to reduce maternal and fetal morbidity. However, real-world clinical deployment of machine learning is hindered…

With the fast evolution of high-throughput technology, longitudinal gene expression experiments have become affordable and increasingly common in biomedical fields. Generalized estimating equation (GEE) approach is a widely used statistical…

Bayesian inference is a widely used technique for real-time characterization of quantum systems. It excels in experimental characterization in the low data regime, and when the measurements have degrees of freedom. A decisive factor for its…

Deep Learning systems have achieved great success in the past few years, even surpassing human intelligence in several cases. As of late, they have also established themselves in the biomedical and healthcare domains, where they have shown…

Major depressive disorder (MDD) is a prevalent psychiatric disorder that is associated with significant healthcare burden worldwide. Phenotyping of MDD can help early diagnosis and consequently may have significant advantages in patient…

There has been an increased interest in applying deep neural networks to automatically interpret and analyze the 12-lead electrocardiogram (ECG). The current paradigms with machine learning methods are often limited by the amount of labeled…

Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial persistence. To understand the strategy to control such…

Respiration rate (RR) is an important vital sign for clinical monitoring of hospitalized patients, with changes in RR being strongly tied to changes in clinical status leading to adverse events. Human labels for RR, based on counting…

Nonsense-mediated mRNA decay (NMD) is a critical post-transcriptional surveillance mechanism that degrades transcripts with premature termination codons, safeguarding transcriptome integrity and shaping disease phenotypes. However,…

We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core…

Missing data occur frequently in empirical studies in health and social sciences, often compromising our ability to make accurate inferences. An outcome is said to be missing not at random (MNAR) if, conditional on the observed variables,…

Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that…

The expectation-maximization (EM) algorithm and its variants are widely used in statistics. In high-dimensional mixture linear regression, the model is assumed to be a finite mixture of linear regression and the number of predictors is much…

The empirical practice of using factor models to adjust for shared, unobserved confounders, $\mathbf{Z}$, in observational settings with multiple treatments, $\mathbf{A}$, is widespread in fields including genetics, networks, medicine, and…

Non-Alcoholic Fatty Liver Disease (NAFLD) is becoming increasingly prevalent in the world population. Without diagnosis at the right time, NAFLD can lead to non-alcoholic steatohepatitis (NASH) and subsequent liver damage. The diagnosis and…