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The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Efficient learning and model compression algorithm for deep neural network (DNN) is a key workhorse behind the rise of deep learning (DL). In this work, we propose a message passing based Bayesian deep learning algorithm called EM-TDAMP to…

Machine Learning · Computer Science 2024-06-11 Wei Xu , An Liu , Yiting Zhang , Vincent Lau

Hybrid methods have been shown to outperform pure statistical and pure deep learning methods at forecasting tasks and quantifying the associated uncertainty with those forecasts (prediction intervals). One example is Exponential Smoothing…

Machine Learning · Computer Science 2021-12-17 Thabang Mathonsi , Terence L. van Zyl

This paper presents a novel method for autonomously enhancing deep neural network training. My approach employs an Evaluation Neural Network (ENN) trained via deep reinforcement learning to predict the performance of the target network. The…

Machine Learning · Computer Science 2024-06-18 Ryohei Ino

Environmental hazards place certain individuals at disproportionately higher risks. As these hazards increasingly endanger human health, precise identification of the most vulnerable population subgroups is critical for public health.…

Machine Learning · Computer Science 2024-09-23 Jong Woo Nam , Eun Young Choi , Jennifer A. Ailshire , Yao-Yi Chiang

Non alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, which can be predicted accurately to prevent advanced fibrosis and cirrhosis. While, a liver biopsy, the gold standard for NAFLD diagnosis, is…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Yaran Chen , Xueyu Chen , Yu Han , Haoran Li , Dongbin Zhao , Jingzhong Li , Xu Wang

Households represent a key unit of interest in infectious disease epidemiology, in both empirical studies and mathematical modelling. The within-household transmission potential of a disease is often summarised by a secondary attack ratio…

Applications · Statistics 2026-03-27 Joseph Brooks , Thomas House , Lorenzo Pellis , Joe Hilton

From a fresh data science perspective, this thesis discusses the prediction of coronary artery disease based on genetic variations at the DNA base pair level, called Single-Nucleotide Polymorphisms (SNPs), collected from the Ontario Heart…

Machine Learning · Computer Science 2014-02-04 Hubert Haoyang Duan

Electroencephalography (EEG) is a widely used tool for diagnosing brain disorders due to its high temporal resolution, non-invasive nature, and affordability. Manual analysis of EEG is labor-intensive and requires expertise, making…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Salim Rukhsar , Anil Kumar Tiwari

Nearest neighbor (NN) matching as a tool to align data sampled from different groups is both conceptually natural and practically well-used. In a landmark paper, Abadie and Imbens (2006) provided the first large-sample analysis of NN…

Statistics Theory · Mathematics 2021-12-28 Zhexiao Lin , Peng Ding , Fang Han

This work presents the development and evaluation of an NLP-enabled probabilistic classifier designed to estimate the probability of technical and regulatory success (pTRS) for clinical trials in the field of neuroscience. While…

Machine Learning · Computer Science 2025-12-02 Michael R. Doane

In recent days, Artificial Neural Network (ANN) can be applied to a vast majority of fields including business, medicine, engineering, etc. The most popular areas where ANN is employed nowadays are pattern and sequence recognition, novelty…

Computer Vision and Pattern Recognition · Computer Science 2019-02-06 Md. Abu Bakr Siddique , Mohammad Mahmudur Rahman Khan , Rezoana Bente Arif , Zahidun Ashrafi

Accurate prediction and identification of variables associated with outcomes or disease states are critical for advancing diagnosis, prognosis, and precision medicine in biomedical research. Regularized regression techniques, such as lasso,…

Applications · Statistics 2025-04-14 Xiaoru Dong , Apoorva Goyal , Muxuan Liang , Maigan A. Brusko , Todd M. Brusko , Rhonda Bacher

Evolutionary computation (EC)-based neural architecture search (NAS) has achieved remarkable performance in the automatic design of neural architectures. However, the high computational cost associated with evaluating searched architectures…

Neural and Evolutionary Computing · Computer Science 2025-05-01 Yangyang Li , Guanlong Liu , Ronghua Shang , Licheng Jiao

We present a semi-supervised algorithm for lung cancer screening in which a 3D Convolutional Neural Network (CNN) is trained using the Expectation-Maximization (EM) meta-algorithm. Semi-supervised learning allows a smaller labelled data-set…

Machine Learning · Computer Science 2020-10-06 Sumeet Menon , David Chapman , Phuong Nguyen , Yelena Yesha , Michael Morris , Babak Saboury

Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disorder characterized by the excessive accumulation of fat in the liver in individuals who do not consume significant amounts of alcohol, including risk factors like…

Quantitative Methods · Quantitative Biology 2023-11-16 Tahmina Sultana Priya , Fan Leng , Anthony C. Luehrs , Eric W. Klee , Alina M. Allen , Konstantinos N. Lazaridis , Danfeng , Yao , Shulan Tian

Since no effective therapies exist for Alzheimer's disease (AD), prevention has become more critical through lifestyle factor changes and interventions. Analyzing electronic health records (EHR) of patients with AD can help us better…

Computation and Language · Computer Science 2021-01-26 Zitao Shen , Yoonkwon Yi , Anusha Bompelli , Fang Yu , Yanshan Wang , Rui Zhang

Rare diseases (RDs) are collectively common and affect 300 million people worldwide. Accurate phenotyping is critical for informing diagnosis and treatment, but RD phenotypes are often embedded in unstructured text and time-consuming to…

Computation and Language · Computer Science 2024-06-28 Cathy Shyr , Yan Hu , Paul A. Harris , Hua Xu

Emergency department's (ED) boarding (defined as ED waiting time greater than four hours) has been linked to poor patient outcomes and health system performance. Yet, effective forecasting models is rare before COVID-19, lacking during the…

Machine Learning · Computer Science 2024-03-22 Eman Leung , Jingjing Guan , Kin On Kwok , CT Hung , CC. Ching , CK. Chung , Hector Tsang , EK Yeoh , Albert Lee

Deep directed generative models have attracted much attention recently due to their expressive representation power and the ability of ancestral sampling. One major difficulty of learning directed models with many latent variables is the…

Machine Learning · Computer Science 2015-06-16 Siqi Nie , Qiang Ji