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Bacteria seem masters of chemotaxis, yet recent work suggests otherwise. Henry Mattingly and colleagues (Nature Physics, 2026) argue that Escherichia coli uses only a small fraction of the sensory information available at its surface,…

Cell Behavior · Quantitative Biology 2026-01-16 Robert G. Endres

Organisms must acquire and use environmental information to guide their behaviors. However, it is unclear whether and how information quantitatively limits behavioral performance. Here, we relate information to behavioral performance in…

Biological Physics · Physics 2023-02-22 Henry H. Mattingly , Keita Kamino , Benjamin B. Machta , Thierry Emonet

Bacterial chemotaxis has long been viewed as operating near the physical limits of sensing, as originally articulated by Berg and Purcell. Recent information-theoretic analyses challenge this view, suggesting that Escherichia coli uses only…

Cell Behavior · Quantitative Biology 2026-05-06 Robert G. Endres

Bacterial motility, and in particular repulsion or attraction towards specific chemicals, has been a subject of investigation for over 100 years, resulting in detailed understanding of bacterial chemotaxis and the corresponding sensory…

Biological Physics · Physics 2022-06-08 Jerko Rosko , Vincent Martinez , Wilson Poon , Teuta Pilizota

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

Molecular Networks · Quantitative Biology 2019-08-19 Thierry Emonet , Philippe Cluzel

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

Analysis of PDEs · Mathematics 2007-05-23 Radek Erban , Hyung Ju Hwang

In this article we highlight chemotaxis (cellular movement) as a rich source of potential engineering applications and computational models, highlighting current research and possible future work. We first give a brief description of the…

Cell Behavior · Quantitative Biology 2007-05-23 Martyn Amos , David A. Hodgson , Alan Gibbons

Organisms use specialized sensors to measure their environments, but the fundamental principles that determine their accuracy remain largely unknown. In Escherichia coli chemotaxis, we previously found that gradient-climbing speed is…

Biological Physics · Physics 2025-08-28 Henry H. Mattingly , Keita Kamino , Jude Ong , Rafaela Kottou , Thierry Emonet , Benjamin B. Machta

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

Biological Physics · Physics 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

Chemotaxis, the directional locomotion of cells towards a source of a chemical gradient, is an integral part of many biological processes - for example, bacteria motion, single-cell or multicellular organisms development, immune response,…

Analysis of PDEs · Mathematics 2021-03-29 Yishu Gong , Alexander Kiselev

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

Cell Behavior · Quantitative Biology 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Chemotaxis in bacteria such as \textit{E.\ coli} is controlled by the slow methylation of chemoreceptors. As a consequence, intrinsic time and length scales of tens of seconds and hundreds of micrometers emerge, making the Keller--Segel…

Soft Condensed Matter · Physics 2025-04-23 Manuel Mayo , Rodrigo Soto

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

The chemotaxis pathway in the bacterium Escherichia coli allows cells to detect changes in external ligand concentration (e.g. nutrients). The pathway regulates the flagellated rotary motors and hence the cells' swimming behaviour, steering…

Cell Behavior · Quantitative Biology 2011-03-04 Diana Clausznitzer , Robert G Endres

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial populations into previously unoccupied territories.…

Populations and Evolution · Quantitative Biology 2022-06-08 Avaneesh V. Narla , Jonas Cremer , Terry Hwa

The chemotactic network of Escherichia coli has been studied extensively both biophysically and information-theoretically. Nevertheless, the connection between these two aspects is still elusive. In this work, we report such a connection by…

Cell Behavior · Quantitative Biology 2021-03-31 Kento Nakamura , Tetsuya J. Kobayashi

Flagellated bacteria, such as Escherichia coli, perform directed motion in gradients of concentration of attractants and repellents in a process called chemotaxis. The E. coli chemotaxis signaling pathway is a model for signal transduction,…

Biological Physics · Physics 2015-03-11 Anne-Florence Bitbol , Ned S. Wingreen

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

Statistical Mechanics · Physics 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

Biological Physics · Physics 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are…

Biological Physics · Physics 2013-02-13 Benjamin Franz , Chuan Xue , Kevin J. Painter , Radek Erban
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