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Binary regression models are ubiquitous in virtually every scientific field. Frequently, traditional generalized linear models fail to capture the variability in the probability surface that gives rise to the binary observations and novel…
This paper presents our computational methodology using Genetic Algorithms (GA) for exploring the nature of RNA editing. These models are constructed using several genetic editing characteristics that are gleaned from the RNA editing system…
Spoken Language Understanding (SLU) aims to extract the semantics frame of user queries, which is a core component in a task-oriented dialog system. With the burst of deep neural networks and the evolution of pre-trained language models,…
The organization of latent knowledge within large-scale models poses unique challenges when addressing overlapping representations and optimizing contextual accuracy. Conceptual redundancies embedded across layers often result in…
We present an algebraic approach to evolutionary accumulation modelling (EvAM). EvAM is concerned with learning and predicting the order in which evolutionary features accumulate over time. Our approach is complementary to the more common…
Converging evidence suggests that human systems of semantic categories achieve near-optimal compression via the Information Bottleneck (IB) complexity-accuracy tradeoff. Large language models (LLMs) are not trained for this objective, which…
Significant efforts have been devoted in the last decade towards improving the predictivity of coarse-grained models in molecular dynamics simulations and providing a rigorous justification of their use, through a combination of theoretical…
Intuitionistic grammar logics fuse constructive and multi-modal reasoning while permitting the use of converse modalities, serving as a generalization of standard intuitionistic modal logics. In this paper, we provide definitions of these…
Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…
In a paper presented at SOS 2010, we developed a framework for big-step semantics for interactive input-output in combination with divergence, based on coinductive and mixed inductive-coinductive notions of resumptions, evaluation and…
Atomistic or ab-initio molecular dynamics simulations are widely used to predict thermodynamics and kinetics and relate them to molecular structure. A common approach to go beyond the time- and length-scales accessible with such…
We begin by reviewing a technique to approximate the dynamics of stochastic programs --written in a stochastic process algebra-- by a hybrid system, suitable to capture a mixed discrete/continuous evolution. In a nutshell, the discrete…
The modelling, specification and study of the semantics of concurrent reactive systems have been interesting research topics for many years now. The aim of this thesis is to exploit the strengths of the (co)algebraic framework in modelling…
We show how the mathematical structure of large-deviation principles matches well with the concept of coarse-graining. For those systems with a large-deviation principle, this may lead to a general approach to coarse-graining through the…
Understanding the complex interactions within the microbiome is crucial for developing effective diagnostic and therapeutic strategies. Traditional machine learning models often lack interpretability, which is essential for clinical and…
Existing large language model (LLM)-based embeddings typically adopt an encoder-only paradigm, treating LLMs as static feature extractors and overlooking their core generative strengths. We introduce GIRCSE (Generative Iterative Refinement…
Advances in generative artificial intelligence are transforming how metal-organic frameworks (MOFs) are designed and discovered. This Perspective introduces the shift from laborious enumeration of MOF candidates to generative approaches…
We present a novel parsing algorithm for all context-free languages, based on computing the relation between configurations and reaching transitions in a recursive transition network. Parsing complexity w.r.t. input length matches the state…
Rule-based machine translation is more data efficient than the big data-based machine translation approaches, making it appropriate for languages with low bilingual corpus resources -- i.e., minority languages. However, the rule-based…
In this article we explain the theory of rigid residue complexes in commutative algebra and algebraic geometry, summarizing the background, recent results and anticipated future results. Unlike all previous approaches to Grothendiec…