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Biological neural networks are notoriously hard to model due to their stochastic behavior and high dimensionality. We tackle this problem by constructing a dynamical model of both the expectations and covariances of the fractions of active…

Neurons and Cognition · Quantitative Biology 2025-02-25 Vincent Painchaud , Patrick Desrosiers , Nicolas Doyon

Oscillatory synchrony is hypothesized to support the flow of information between brain regions, with different phase-locked configurations enabling activation of different effective interactions. Along these lines, past work has proposed…

Neurons and Cognition · Quantitative Biology 2022-08-26 Lia Papadopoulos , Demian Battaglia , Dani S. Bassett

Regulatory networks describe the interactions between molecular or cellular regulators, like transcription factors and genes in gene regulatory networks, kinases and their receptors in signalling networks, or neurons in neural networks. A…

Molecular Networks · Quantitative Biology 2022-12-29 Niklas Bonacker , Johannes Berg

In this paper we propose a novel control approach for opinion dynamics on evolving networks. The controls modify the strength of connections in the network, rather than influencing opinions directly, with the overall goal of steering the…

Physics and Society · Physics 2024-04-16 Andrew Nugent , Susana N. Gomes , Marie-Therese Wolfram

The control of complex systems is an ongoing challenge of complexity research. Recent advances using concepts of structural control deduce a wide range of control related properties from the network representation of complex systems. Here,…

Statistical Mechanics · Physics 2013-12-31 Márton Pósfai , Philipp Hövel

In this paper, we consider a population of individuals who have actions and opinions, which coevolve, mutually influencing one another on a complex network structure. In particular, we formulate a control problem for this social network, in…

Systems and Control · Electrical Eng. & Systems 2026-05-12 Roberta Raineri , Mengbin Ye , Lorenzo Zino

This paper studies stochastic aperiodic stabilization of a networked control system (NCS) consisting of a continuous-time plant and a discrete-time controller. The plant and the controller are assumed to be connected by communication…

Systems and Control · Electrical Eng. & Systems 2022-03-08 Yohei Hosoe

Controllability of complex networks arises in many technological problems involving social, financial, road, communication, and smart grid networks. In many practical situations, the underlying topology might change randomly with time, due…

Systems and Control · Computer Science 2020-01-08 Fernando Gama , Elvin Isufi , Alejandro Ribeiro , Geert Leus

We consider continuous time Hopfield-like recurrent networks as dynamical models for gene regulation and neural networks. We are interested in networks that contain n high-degree nodes preferably connected to a large number of Ns weakly…

Molecular Networks · Quantitative Biology 2016-08-03 Sergei Vakulenko , Ivan Morozov , Ovidiu Radulescu

To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing on different cognitive systems. How does the brain's network of anatomical connections help facilitate…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Shi Gu , John D. Medaglia , Fabio Pasqualetti , Danielle S. Bassett

Key features of biological activity can often be captured by transitions between a finite number of semi-stable states that correspond to behaviors or decisions. We present here a broad class of dynamical systems that are ideal for modeling…

Dynamical Systems · Mathematics 2022-12-14 Megan Morrison , Lai-Sang Young

Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system's dynamical behavior, for example, detecting key therapeutic targets to control pathways in models of…

Physics and Society · Physics 2023-11-02 Thomas Parmer , Filippo Radicchi

Symmetries are an essential feature of complex networks as they regulate how the graph collective dynamics organizes into clustered states. We here show how to control network symmetries, and how to enforce patterned states of…

Physics and Society · Physics 2020-11-24 L. V. Gambuzza , M. Frasca , F. Sorrentino , L. M. Pecora , S. Boccaletti

Many natural and man-made network systems need to maintain certain patterns, such as working at equilibria or limit cycles, to function properly. Thus, the ability to stabilize such patterns is crucial. Most of the existing studies on…

Optimization and Control · Mathematics 2025-09-30 Alberto Maria Nobili , Yuzhen Qin , Carlo Alberto Avizzano , Danielle S. Bassett , Fabio Pasqualetti

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

We study the target control problem of asynchronous Boolean networks, to identify a set of nodes, the perturbation of which can drive the dynamics of the network from any initial state to the desired steady state (or attractor). We are…

Systems and Control · Electrical Eng. & Systems 2020-06-04 Cui Su , Jun Pang

Feedback control is an effective strategy for stabilizing a desired state and has been widely adopted in maintaining the stability of systems such as flying birds and power grids. By default, this framework requires continuous control input…

Adaptation and Self-Organizing Systems · Physics 2025-10-14 Yuanzhao Zhang , Sean P. Cornelius

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

Methodology · Statistics 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

A properly designed controller can help improve the quality of experimental measurements or force a dynamical system to follow a completely new time-evolution path. Recent developments in deep reinforcement learning have made steep advances…

Statistical Mechanics · Physics 2025-02-26 Ruslan Mukhamadiarov

A fundamental premise of statistical physics is that the particles in a physical system are interchangeable, and hence the state of each specific component is representative of the system as a whole. This assumption breaks down for complex…

Physics and Society · Physics 2025-12-16 Neil G. MacLaren , Baruch Barzel , Naoki Masuda
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